| Title : Leveraging multitargeting BChE-MAO B inhibitors against microglia-related neuroinflammation: in vitro biological evaluation, structure-activity relationships, drug-like properties, and X-ray crystal complexes - Rullo_2026_Eur.J.Med.Chem_316_118961 |
| Author(s) : Rullo M , La Spada G , Brazzolotto X , Marchese S , El Idrissi IG , Miciaccia M , Colella M , Brea JM , Macchia E , Loza MI , Gottinger A , Scilimati A , Perrone MG , Stefanachi A , Binda C , Leonetti F , Pisani L |
| Ref : European Journal of Medicinal Chemistry , :118961 , 2026 |
| Abstract : |
| PubMedSearch : Rullo_2026_Eur.J.Med.Chem_316_118961 |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases - Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| Author(s) : Knez D , Diez-Iriepa D , Chioua M , Gottinger A , Denic M , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Meden A , Pislar A , Kos J , Zakelj S , Stojan J , Salat K , Serrano J , Patricia Fernandez AP , Sanchez-Garcia A , Martinez-Murillo R , Binda C , Lopez-Munoz F , Gobec S , Marco-Contelles J |
| Ref : Acta Pharmaceutica Sinica B , 13 :2152 , 2023 |
| Abstract : |
| PubMedSearch : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| PubMedID: 37250172 |
| Gene_locus related to this paper: human-BCHE |
| Title : Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures - Ekstrom_2022_ACS.Med.Chem.Lett_13_499 |
| Author(s) : Ekstrom F , Gottinger A , Forsgren N , Catto M , Iacovino LG , Pisani P , Binda C |
| Ref : ACS Med Chem Lett , 13 :499 , 2022 |
| Abstract : |
| PubMedSearch : Ekstrom_2022_ACS.Med.Chem.Lett_13_499 |
| PubMedID: 35300078 |
| Gene_locus related to this paper: mouse-ACHE |