9LBT
Name : Crystal structure of human DPP4 DPPIV in complex with tetrapeptide VAMP (Val-Ala-Met-Pro)
Revelation date : 23-Jul-2025
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Chen, H.H.,Xing, X.H.
Ligand : Inhibitor Val-Ala-Met-Pro Ligand in structure: Ligplot
References (2)
| Title : Discovery of a novel tetrapeptide as glucose homeostasis modulator with bifunctionalities of targeting DPP-IV and microbiota - Chen_2025_Imeta_4_e70072 |
| Author(s) : Chen H , Li W , Hu W , Liu J , Zhang C , Wang Y , Zhang X , Chen S , Nie Q , Xing X |
| Ref : Imeta , 4 :e70072 , 2025 |
| Abstract : |
| PubMedSearch : Chen_2025_Imeta_4_e70072 |
| PubMedID: 41112055 |
| Gene_locus related to this paper: human-DPP4 |
| Title : A novel bifunctional peptide VAMP mined from hemp seed protein hydrolysates improves glucose homeostasis by inhibiting intestinal DPP-IV and increasing the abundance of Akkermansia muciniphila - Chen_2024_bioRxiv__ |
| Author(s) : Chen H , Li W , Hu W , Xu B , Wang Y , Liu J , Zhang C , Zhang X , Nie Q , Xing XH |
| Ref : bioRxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Chen_2024_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 9LBT Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9LBT Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9LBT Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9LBT 3D, interactive encyclopedia of proteins - PROTEOPEDIA server