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Structure Report for: 4ARB

Name|Mus musculus Acetylcholinesterase in complex with (S)-C5685 at 2.25 A resolution.
Revelation date|28-Nov-2012
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|mouse-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Berg, L., Niemiec, M., Qian, W., Andersson, C.-D., WittungStafshede, P., Ekstrom, F., Linusson, A.
Ligand|Inhibitor: C5685 Ligand in structure: Ligplot


Reference

    Title: Similar but different: thermodynamic and structural characterization of a pair of enantiomers binding to acetylcholinesterase
    Berg L, Niemiec MS, Qian W, Andersson CD, Wittung-Stafshede P, Ekstrom F, Linusson A
    Ref: Angew Chem Int Ed Engl, 51:12716, 2012 : PubMed

            

    Title: Targeting acetylcholinesterase: identification of chemical leads by high throughput screening, structure determination and molecular modeling
    Berg L, Andersson CD, Artursson E, Hornberg A, Tunemalm AK, Linusson A, Ekstrom F
    Ref: PLoS ONE, 6:e26039, 2011 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum4ARB Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4ARB Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4ARB Structural Classification Of Protein - SCOP server
PROTEOPEDIA4arb 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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