Dilazep
potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties. It has a role as a vasodilator agent, a platelet aggregation inhibitor and a cardioprotective agent. Human equilibrative nucleoside transporter-1, 8DZ dilazep bound 6OB7
General
Type : Drug, Not A\/B H target, Pro-Drug, Diazepane
Chemical_Nomenclature : 3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate
Canonical SMILES : COC1=CC(=CC(=C1OC)OC)C(=O)OCCCN2CCCN(CC2)CCCOC(=O)C3=CC(=C(C(=C3)OC)OC)OC
InChI : InChI=1S\/C31H44N2O10\/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4\/h18-21H,7-17H2,1-6H3
InChIKey : QVZCXCJXTMIDME-UHFFFAOYSA-N
Other name(s) : F8KLC2BD5Z || CHEMBL126075 || DTXSID9045425 || 3,3'-(1,4-Diazepan-1,4-diyl)dipropyl bis(3,4,5-trimethoxybenzoat) || SCHEMBL48830 || CHEBI:92842
MW : 604.7
Formula : C31H44N2O10
CAS_number : 35898-87-4
PubChem : 3074
UniChem : QVZCXCJXTMIDME-UHFFFAOYSA-N
Target
Structures : No structure
Families : Carb_B_Chordata
References (1)
| Title : Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver - Takai_1997_Biol.Pharm.Bull_20_869 |
| Author(s) : Takai S , Matsuda A , Usami Y , Adachi T , Sugiyama T , Katagiri Y , Tatematsu M , Hirano K |
| Ref : Biol Pharm Bull , 20 :869 , 1997 |
| Abstract : |
| PubMedSearch : Takai_1997_Biol.Pharm.Bull_20_869 |
| PubMedID: 9300133 |
| Gene_locus related to this paper: human-CES1 , human-CES2 |