IPAN

Near-infrared emission fluorescent probe (IPAN) for visualization of ChE activity showed a significant enhancement of ChE activity in the tumor cells and brain glioma. IPAN is hydrolyzed into IPAH which is fluorescent

General

Type : Carbamate, Cyanide, Fluorescent Probe, Near-Infrared fluorescent Probe

Chemical_Nomenclature : 2-(3-ethenyl-5,5-dimethylcyclohex-2-en-1-ylidene)propanedinitrile phenyldimethylcarbamate

Canonical SMILES : C1C(CC(=CC1=C(C#N)C#N)C=CC2=CC=C(C=C2)OC(=O)N(C)C)(C)C

InChI : InChI=1S\/C22H23N3O2\/c1-22(2)12-17(11-18(13-22)19(14-23)15-24)6-5-16-7-9-20(10-8-16)27-21(26)25(3)4\/h5-11H,12-13H2,1-4H3

InChIKey : RXCATQMXCKMZEF-AATRIKPKSA-N

Other name(s) :


MW : 361.44

Formula : C22H23N3O2

CAS_number :

PubChem :

UniChem : RXCATQMXCKMZEF-AATRIKPKSA-N

Target

Structures : No structure

Families : BCHE, ACHE

References (1)

Title : Observation of the elevation of cholinesterases activity in brain glioma by a near-infrared emission chemsensor - Ma_2020_Anal.Chem_92_13405
Author(s) : Ma Y , Gao W , Ma S , Liu Y , Lin W
Ref : Analytical Chemistry , 92(19):13405-13410 : , 2020
Abstract :
PubMedSearch : Ma_2020_Anal.Chem_92_13405
PubMedID: 32864956