Leucomycin-A1
General
Type : Macrolide, Polyketide, Natural, Antibiotic
Chemical_Nomenclature : [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate'
Canonical SMILES : C[C@@H]1C\/C=C\/C=C\/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)O
InChI : InChI=1S\/C40H67NO14\/c1-22(2)18-30(45)53-38-26(6)51-32(21-40(38,7)48)54-35-25(5)52-39(34(47)33(35)41(8)9)55-36-27(16-17-42)19-23(3)28(43)15-13-11-12-14-24(4)50-31(46)20-29(44)37(36)49-10\/h11-13,15,17,22-29,32-39,43-44,47-48H,14,16,18-21H2,1-10H3\/b12-11+,15-13+\/t23-,24-,25-,26+,27+,28+,29-,32+,33-,34-,35-,36+,37+,38+,39+,40-\/m1\/s1
InChIKey : IEMDOFXTVAPVLX-YWQHLDGFSA-N
Other name(s) : Leucomycin A1 || Kitasamycin A5 || Kitasamycin A1 || Turimycin H5 || 3-Deacetyljosamycin || Leucomycin V 4-isovalerate
MW : 786.0
Formula : C40H67NO14
CAS_number :
PubChem : 5282322
UniChem : IEMDOFXTVAPVLX-YWQHLDGFSA-N
Target
Structures : No structure
Families : Aclacinomycin-methylesterase_RdmC
References (1)
| Title : Functional characterization of macrolide esterase from cyanobacteria and their potential dissemination risk - Tao_2026_NPJ.Antimicrob.Resist_4_10 |
| Author(s) : Tao H , Zhou L , Zhou Y , Wang Y , Lv H , Wang T , Xu C , Chu Y , Wang X , Song T , Lin J |
| Ref : NPJ Antimicrob Resist , 4 :10 , 2026 |
| Abstract : |
| PubMedSearch : Tao_2026_NPJ.Antimicrob.Resist_4_10 |
| PubMedID: 41699255 |
| Gene_locus related to this paper: 9cyan-a0a927enu2 , 9cyan-OCA.1 , 9cyan-OCB.1 |