Methyl-Gallate
anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties || AoPrbA wild type did not hydrolyze gallic acid methyl ester, whereas the Thr200Glu, Leu232Gln, and Leu428Ser variants did, indicating that these three variants acquired tannase activity. In particular, the Leu428Ser variant exhibited considerably greater hydrolysis of gallic acid and protocatechuic acid methyl esters
General
Type : Derivative of Gallate, Benzoate, Natural
Chemical_Nomenclature : methyl 3,4,5-trihydroxybenzoate
Canonical SMILES : COC(=O)C1=CC(=C(C(=C1)O)O)O
InChI : InChI=1S\/C8H8O5\/c1-13-8(12)4-2-5(9)7(11)6(10)3-4\/h2-3,9-11H,1H3
InChIKey : FBSFWRHWHYMIOG-UHFFFAOYSA-N
Other name(s) : Methyl Gallate || Methyl 3,4,5-trihydroxybenzoate || CHEMBL65675 || SCHEMBL39513 || ZINC21789 || CHEBI:145828 || MG || Gallic acid methyl ester || Methylgallate
MW : 184.15
Formula : C8H8O5
CAS_number : 99-24-1
PubChem : 7428
UniChem : FBSFWRHWHYMIOG-UHFFFAOYSA-N
Target
Structures : No structure
Families : Tannase, Plant_carboxylesterase, Tannase_Bact
References (12)
| Title : Structure-based clustering and mutagenesis of bacterial tannases reveals the importance and diversity of active site-capping domains - Coleman_2024_Protein.Sci_33_e5202 |
| Author(s) : Coleman T , Viknander S , Kirk AM , Sandberg D , Caron E , Zelezniak A , Krenske E , Larsbrink J |
| Ref : Protein Science , 33 :e5202 , 2024 |
| Abstract : |
| PubMedSearch : Coleman_2024_Protein.Sci_33_e5202 |
| PubMedID: 39555646 |
| Gene_locus related to this paper: clobu-CbTan2 , clobu-c4ibl3 , clobu-c4ic90 , fusnn-FN0616 , lacpl-tanL |
| Title : Assay Analysis of Tannase from Lactobacillus plantarum - Kanauchi_2024_Methods.Mol.Biol_2851_87 |
| Author(s) : Kanauchi M |
| Ref : Methods Mol Biol , 2851 :87 , 2024 |
| Abstract : |
| PubMedSearch : Kanauchi_2024_Methods.Mol.Biol_2851_87 |
| PubMedID: 39210173 |
| Gene_locus related to this paper: lacpl-tanL |
| Title : Substrate specificity modification of paraben hydrolase and tannase from Aspergillus oryzae - Hakoda_2024_Enzyme.Microb.Technol_180_110495 |
| Author(s) : Hakoda M , Kato T , Takahashi C , Shiono Y , Koseki T |
| Ref : Enzyme Microb Technol , 180 :110495 , 2024 |
| Abstract : |
| PubMedSearch : Hakoda_2024_Enzyme.Microb.Technol_180_110495 |
| PubMedID: 39121638 |
| Gene_locus related to this paper: aspor-q2uh24 , aspor-tan |
| Title : Discovery and characterization of tannase genes in plants: roles in hydrolysis of tannins - Dai_2020_New.Phytol_226_1104 |
| Author(s) : Dai X , Liu Y , Zhuang J , Yao S , Liu L , Jiang X , Zhou K , Wang Y , Xie D , Bennetzen JL , Gao L , Xia T |
| Ref : New Phytol , 226 :1104 , 2020 |
| Abstract : |
| PubMedSearch : Dai_2020_New.Phytol_226_1104 |
| PubMedID: 32061142 |
| Gene_locus related to this paper: camsi-a0a5b9g8c2 , jugre-JrTA , fraan-FaTA , vitvi-VvTA , citcl-CcTA , dioka-DkTA , camsi-CsTA |
| Title : Mutational analysis of Kex2 recognition sites and a disulfide bond in tannase from Aspergillus oryzae - Koseki_2017_Biochem.Biophys.Res.Commun_482_1165 |
| Author(s) : Koseki T , Otsuka M , Mizuno T , Shiono Y |
| Ref : Biochemical & Biophysical Research Communications , 482 :1165 , 2017 |
| Abstract : |
| PubMedSearch : Koseki_2017_Biochem.Biophys.Res.Commun_482_1165 |
| PubMedID: 27919681 |
| Gene_locus related to this paper: aspor-tan |
| Title : A Lactobacillus plantarum Esterase Active on a Broad Range of Phenolic Esters - Esteban-Torres_2015_Appl.Environ.Microbiol_81_3235 |
| Author(s) : Esteban-Torres M , Landete JM , Reveron I , Santamaria L , de Las Rivas B , Munoz R |
| Ref : Applied Environmental Microbiology , 81 :3235 , 2015 |
| Abstract : |
| PubMedSearch : Esteban-Torres_2015_Appl.Environ.Microbiol_81_3235 |
| PubMedID: 25746986 |
| Gene_locus related to this paper: lacpl-Est.1092 |
| Title : Gallic acid-based alkyl esters synthesis in a water-free system by celite-bound lipase of Bacillus licheniformis SCD11501 - Sharma_2015_Biotechnol.Prog_31_715 |
| Author(s) : Sharma S , Kanwar SS , Dogra P , Chauhan GS |
| Ref : Biotechnol Prog , 31 :715 , 2015 |
| Abstract : |
| PubMedSearch : Sharma_2015_Biotechnol.Prog_31_715 |
| PubMedID: 25737230 |
| Title : Tannin degradation by a novel tannase enzyme present in some Lactobacillus plantarum strains - Jimenez_2014_Appl.Environ.Microbiol_80_2991 |
| Author(s) : Jimenez N , Esteban-Torres M , Mancheno JM , de Las Rivas B , Munoz R |
| Ref : Applied Environmental Microbiology , 80 :2991 , 2014 |
| Abstract : |
| PubMedSearch : Jimenez_2014_Appl.Environ.Microbiol_80_2991 |
| PubMedID: 24610854 |
| Gene_locus related to this paper: lacpn-d7vbf4 |
| Title : Catalytical Properties of Free and Immobilized Aspergillus niger Tannase - Flores-Maltos_2011_Enzyme.Res_2011_768183 |
| Author(s) : Flores-Maltos A , Rodriguez-Duran LV , Renovato J , Contreras JC , Rodriguez R , Aguilar CN |
| Ref : Enzyme Res , 2011 :768183 , 2011 |
| Abstract : |
| PubMedSearch : Flores-Maltos_2011_Enzyme.Res_2011_768183 |
| PubMedID: 21918717 |
| Title : Acidophilic tannase from marine Aspergillus awamori BTMFW032 - Beena_2010_J.Microbiol.Biotechnol_20_1403 |
| Author(s) : Beena PS , Soorej MB , Elyas KK , Sarita GB , Chandrasekaran M |
| Ref : J Microbiol Biotechnol , 20 :1403 , 2010 |
| Abstract : |
| PubMedSearch : Beena_2010_J.Microbiol.Biotechnol_20_1403 |
| PubMedID: 21030825 |
| Title : Purification and characterization of two cold-adapted extracellular tannin acyl hydrolases from an Antarctic strain Verticillium sp. P9 - Kasieczka-Burnecka_2007_Appl.Microbiol.Biotechnol_77_77 |
| Author(s) : Kasieczka-Burnecka M , Kuc K , Kalinowska H , Knap M , Turkiewicz M |
| Ref : Applied Microbiology & Biotechnology , 77 :77 , 2007 |
| Abstract : |
| PubMedSearch : Kasieczka-Burnecka_2007_Appl.Microbiol.Biotechnol_77_77 |
| PubMedID: 17786433 |
| Title : Visual reading method for detection of bacterial tannase - Osawa_1993_Appl.Environ.Microbiol_59_1251 |
| Author(s) : Osawa R , Walsh TP |
| Ref : Applied Environmental Microbiology , 59 :1251 , 1993 |
| Abstract : |
| PubMedSearch : Osawa_1993_Appl.Environ.Microbiol_59_1251 |
| PubMedID: 16348918 |