Rufinamide
Rufinamide anticonvulsant in severe forms of seizure disorders. In Lennox-Gastuat syndrome, a form of childhood epilepsy.
General
Type : Drug, Not A\/B H target, Carboxamide, Triazol
Chemical_Nomenclature : (1-[(2,6-difluorophenyl)methyl]triazole-4-carboxamide
Canonical SMILES : C1=CC(=C(C(=C1)F)CN2C=C(N=N2)C(=O)N)F
InChI : InChI=1S\/C10H8F2N4O\/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16\/h1-3,5H,4H2,(H2,13,17)
InChIKey : POGQSBRIGCQNEG-UHFFFAOYSA-N
Other name(s) : Banzel || Inovelon || 1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
MW : 238.19
Formula : C10H8F2N4O
CAS_number : 106308-44-5
PubChem : 129228
UniChem : POGQSBRIGCQNEG-UHFFFAOYSA-N
Target
Structures : No structure
Families : Carb_B_Chordata
References (2)
| Title : Drug-Drug Interaction Potential of Remimazolam Mediated by CYP 450, Transporters, and Protein Binding - Petersen_2024_Curr.Drug.Metab__2 |
| Author(s) : Petersen KU , Schmalix W , Pesic M , Stohr T |
| Ref : Curr Drug Metab , : , 2024 |
| Abstract : |
| PubMedSearch : Petersen_2024_Curr.Drug.Metab__2 |
| PubMedID: 38818914 |
| Gene_locus related to this paper: human-CES1 |
| Title : Investigation of the metabolism of rufinamide and its interaction with valproate - Williams_2011_Drug.Metab.Lett_5_280 |
| Author(s) : Williams ET , Carlson JE , Lai WG , Wong YN , Yoshimura T , Critchley DJ , Narurkar M |
| Ref : Drug Metab Lett , 5 :280 , 2011 |
| Abstract : |
| PubMedSearch : Williams_2011_Drug.Metab.Lett_5_280 |
| PubMedID: 22022867 |