Spiramycin
General
Type : Macrolide, Polyketide, Natural, Antibiotic
Chemical_Nomenclature : 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
Canonical SMILES : C[C@@H]1C\/C=C\/C=C\/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O[C@H]4CC[C@@H]([C@H](O4)C)N(C)C
InChI : InChI=1S\/C43H74N2O14\/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34\/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3\/b13-12+,16-14+\/t24-,25-,26-,27-,28+,29+,30+,31-,32+,34+,35+,36-,37-,38-,39+,40+,41+,42+,43-\/m1\/s1
InChIKey : ACTOXUHEUCPTEW-CEUOBAOPSA-N
Other name(s) : Spiramycin I || Foromacidin A || Foromacidine A || 033ECH6IFG || Spiramycin A || Spiramycin 1 || Demycarosylturimycin H
MW : 843.1
Formula : C43H74N2O14
CAS_number : 24916-50-5
PubChem : 5289394
UniChem : ACTOXUHEUCPTEW-CEUOBAOPSA-N
Target
Structures : No structure
Families : Aclacinomycin-methylesterase_RdmC
References (3)
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |
| Title : Global distribution of alpha\/beta hydrolase family macrolide esterases in Gram-positive bacteria - Zhou_2025_Isme.j__ |
| Author(s) : Zhou Y , Yang Y , Mao Y , Hou Z , Xu Y , Zhao K , Chu Y , Wang X , Wang C , Li S , Xu F , Hao L , Xie B , Lin J , Song T |
| Ref : Isme J , : , 2025 |
| Abstract : |
| PubMedSearch : Zhou_2025_Isme.j__ |
| PubMedID: 41294648 |
| Gene_locus related to this paper: bacce-q736x9 , bacce-mleBCB.1 , 9bacl-mlePBB.1 , cytfi-mleCBF.1 , paesp-mlePBA.1 , brebn-c0z8w7 |