Suc-Gly-Pro-AMC
General
Type : Coumarin, Chromen, 7-amido-4-methylcoumarin, Peptide, Pyrrolidine
Chemical_Nomenclature : 4-[[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-4-oxobutanoic acid
Canonical SMILES : CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@@H]3CCCN3C(=O)CNC(=O)CCC(=O)O
InChI : InChI=1S\/C21H23N3O7\/c1-12-9-20(29)31-16-10-13(4-5-14(12)16)23-21(30)15-3-2-8-24(15)18(26)11-22-17(25)6-7-19(27)28\/h4-5,9-10,15H,2-3,6-8,11H2,1H3,(H,22,25)(H,23,30)(H,27,28)\/t15-\/m0\/s1
InChIKey : NKEPCOOQNLGSLJ-HNNXBMFYSA-N
Other name(s) : 4-[[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-4-oxobutanoic acid || MFCD00038445 || Fmoc-Arg(NO?)-OH || orb1982899 || SCHEMBL29543689 || SCHEMBL29543824 || 7-(succinyl-Gly-Pro)-4-methylcoumarinamide
MW : 429.4
Formula : C21H23N3O7
CAS_number : 80049-85-0
PubChem : 21121742
UniChem : NKEPCOOQNLGSLJ-HNNXBMFYSA-N
Target
Structures : No structure
Families : S9N_PPCE_Peptidase_S9
References (9)
| Title : The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy - Kilpelainen_2020_Biomed.Pharmacother_128_110253 |
| Author(s) : Kilpelainen TP , Hellinen L , Vrijdag J , Yan X , Svarcbahs R , Vellonen KS , Lambeir AM , Huttunen H , Urtti A , Wallen EAA , Myohanen TT |
| Ref : Biomed Pharmacother , 128 :110253 , 2020 |
| Abstract : |
| PubMedSearch : Kilpelainen_2020_Biomed.Pharmacother_128_110253 |
| PubMedID: 32447211 |
| Gene_locus related to this paper: human-PREPL , pig-ppce |
| Title : The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy - Kilpelainen_2020_Biomed.Pharmacother_128_110253 |
| Author(s) : Kilpelainen TP , Hellinen L , Vrijdag J , Yan X , Svarcbahs R , Vellonen KS , Lambeir AM , Huttunen H , Urtti A , Wallen EAA , Myohanen TT |
| Ref : Biomed Pharmacother , 128 :110253 , 2020 |
| Abstract : |
| PubMedSearch : Kilpelainen_2020_Biomed.Pharmacother_128_110253 |
| PubMedID: 32447211 |
| Gene_locus related to this paper: human-PREPL , pig-ppce |
| Title : The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy - Kilpelainen_2020_Biomed.Pharmacother_128_110253 |
| Author(s) : Kilpelainen TP , Hellinen L , Vrijdag J , Yan X , Svarcbahs R , Vellonen KS , Lambeir AM , Huttunen H , Urtti A , Wallen EAA , Myohanen TT |
| Ref : Biomed Pharmacother , 128 :110253 , 2020 |
| Abstract : |
| PubMedSearch : Kilpelainen_2020_Biomed.Pharmacother_128_110253 |
| PubMedID: 32447211 |
| Gene_locus related to this paper: human-PREPL , pig-ppce |
| Title : Activity of dipeptidyl peptidase IV and post-proline cleaving enzyme in sera from osteoporotic patients - Gotoh_1988_Clin.Chem_34_2499 |
| Author(s) : Gotoh H , Hagihara M , Nagatsu T , Iwata H , Miura T |
| Ref : Clinical Chemistry , 34 :2499 , 1988 |
| Abstract : |
| PubMedSearch : Gotoh_1988_Clin.Chem_34_2499 |
| PubMedID: 2904308 |
| Title : Activity of dipeptidyl peptidase IV and post-proline cleaving enzyme in sera from osteoporotic patients - Gotoh_1988_Clin.Chem_34_2499 |
| Author(s) : Gotoh H , Hagihara M , Nagatsu T , Iwata H , Miura T |
| Ref : Clinical Chemistry , 34 :2499 , 1988 |
| Abstract : |
| PubMedSearch : Gotoh_1988_Clin.Chem_34_2499 |
| PubMedID: 2904308 |
| Title : Activity of dipeptidyl peptidase IV and post-proline cleaving enzyme in sera from osteoporotic patients - Gotoh_1988_Clin.Chem_34_2499 |
| Author(s) : Gotoh H , Hagihara M , Nagatsu T , Iwata H , Miura T |
| Ref : Clinical Chemistry , 34 :2499 , 1988 |
| Abstract : |
| PubMedSearch : Gotoh_1988_Clin.Chem_34_2499 |
| PubMedID: 2904308 |
| Title : Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues - Kato_1980_Mol.Cell.Biochem_32_117 |
| Author(s) : Kato T , Okada M , Nagatsu T |
| Ref : Molecular & Cellular Biochemistry , 32 :117 , 1980 |
| Abstract : |
| PubMedSearch : Kato_1980_Mol.Cell.Biochem_32_117 |
| PubMedID: 7007867 |
| Title : Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues - Kato_1980_Mol.Cell.Biochem_32_117 |
| Author(s) : Kato T , Okada M , Nagatsu T |
| Ref : Molecular & Cellular Biochemistry , 32 :117 , 1980 |
| Abstract : |
| PubMedSearch : Kato_1980_Mol.Cell.Biochem_32_117 |
| PubMedID: 7007867 |
| Title : Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues - Kato_1980_Mol.Cell.Biochem_32_117 |
| Author(s) : Kato T , Okada M , Nagatsu T |
| Ref : Molecular & Cellular Biochemistry , 32 :117 , 1980 |
| Abstract : |
| PubMedSearch : Kato_1980_Mol.Cell.Biochem_32_117 |
| PubMedID: 7007867 |