FLAP inhibitor
General
A FLAP inhibitor (5-Lipoxygenase-Activating Protein inhibitor) blocks the FLAP protein, stopping it from helping produce leukotrienes, powerful inflammatory chemicals involved in conditions like asthma, coronary artery disease, and rheumatoid arthritis. By preventing the activation of 5-lipoxygenase (5-LOX) and the release of leukotrienes, these inhibitors reduce inflammation. Used as building blocks of Multi-target drug ligand MTDL
| Inhibitor | Main targeted enzyme families | Type | Structure |
|---|---|---|---|
| Diflapolin | Epoxide_hydrolase | Urea derivative Multitarget Thiazole Benzothiazol Sulfur Compound FLAP inhibitor Organochlorine |
|