Sodium-glucose cotransporter 2
General
Sodium-glucose cotransporter 2 (SGLT2) is a kidney protein that reabsorbs glucose and sodium back into the bloodstream, preventing them from being lost in urine, but SGLT2 inhibitors are a class of diabetes drugs that block this protein, causing excess glucose to be excreted, which lowers blood sugar and offers benefits for heart and kidney health, including weight loss and reduced blood pressure. Used as building blocks of Multi-target drug ligand MTDL
| Inhibitor | Main targeted enzyme families | Type | Structure |
|---|---|---|---|
| Empagliflozin | ACHE | Drug Multitarget Sodium-glucose cotransporter 2 Glycoside Organochlorine |
|
| Canagliflozin | ACHE | Drug Multitarget Sodium-glucose cotransporter 2 Thiophen Sulfur Compound Glycoside |
|