Benzodiazepin
Benzodiazepine is the fusion of a benzene ring and a diazepine ring. Drugs which lower brain activity (diazepam Valium) enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor. Not A\/B hydrolase targets but some prodrugs are substrates of esterases
| Substrate | Main targeted enzyme families | Type | Structure |
|---|---|---|---|
| Remimazolam | Carb_B_Chordata | Benzodiazepin Not AlphaBeta Hydrolase target Drug Propionate Azepane |
|
| Iomazenil | Carb_B_Chordata | Benzodiazepin Not AlphaBeta Hydrolase target Drug Azepane |
|
| W22-methyl-ester | Bacterial_esterase Canar_LipB | Benzodiazepin Not AlphaBeta Hydrolase target Drug Pro-Drug Azepane |
|