Homoserine
Homoserine (isothreonine) is an alpha-amino acid with the chemical formula HO2CCH(NH2)CH2CH2OH. AHL-acylase inactivates N-acyl homoserine lactone (AHL) quorum sensing signal molecules. derivatives of Homoserin are inhibitors or substrate of this family of enzyme
| Substrate | Main targeted enzyme families | Type | Structure |
|---|---|---|---|
| N-3-oxo-dodecanoyl-L-homoserine-lactone | Lactone Dodecanoate Homoserine |
|
|
| C4-HSL | AlphaBeta_hydrolase | Lactone Homoserine |
|
| C6-HSL | AHL-acylase 6_AlphaBeta_hydrolase | Lactone Homoserine |
|
| C8-HSL | 6_AlphaBeta_hydrolase | Lactone Homoserine |
|
| L-homoserine | Homoserine_transacetylase | Peptide Homoserine |
|
| 3-oxo-C12-HSL | AHL-acylase | Lactone Dodecanoate Homoserine |
|