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Profen pro-drug

Ibuprofen (iso-butyl-phenyl-propionic acid) is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating pain, fever, and inflammation. Prodrugs have been designed for longer effect
Substrate Main targeted enzyme families Type Structure
Naproxen-Ethyl-Ester Canar_LipB 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Naphthalen Propionate
Naproxen-Methyl-Ester 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Naphthalen Propionate
Ibuprofen-Ethyl-Ester Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Propionate
Ketoprofen-Glycerol-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Propionate
Ketoprofen-Vinyl-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Butyl-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Ethyl-Ester CarbLipBact_1 Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Lipase_2 Canar_LipB Profen pro-drug Pro-Drug Drug Alkyl ester Propionate
Naproxen-Ethyl-Ester Canar_LipB 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Naphthalen Propionate
Naproxen-Methyl-Ester 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Naphthalen Propionate
Ibuprofen-Ethyl-Ester Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Propionate
Ketoprofen-Glycerol-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Propionate
Ketoprofen-Vinyl-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Butyl-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Ethyl-Ester CarbLipBact_1 Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Lipase_2 Canar_LipB Profen pro-drug Pro-Drug Drug Alkyl ester Propionate
Naproxen-Ethyl-Ester Canar_LipB 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Naphthalen Propionate
Naproxen-Methyl-Ester 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Naphthalen Propionate
Ibuprofen-Ethyl-Ester Hormone-sensitive_lipase_like Profen pro-drug Pro-Drug Drug Propionate
Ketoprofen-Glycerol-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Propionate
Ketoprofen-Vinyl-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Butyl-Ester Canar_LipB Profen pro-drug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Ethyl-Ester CarbLipBact_1 Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Lipase_2 Canar_LipB Profen pro-drug Pro-Drug Drug Alkyl ester Propionate