SNAC
N-acetylcysteamine (SNAC) thioester derivative of macrolide, served as analog of the natural ACP bound substrate in the last reaction of thioesterase which liberate macrolide from ACP.
| Substrate | Main targeted enzyme families | Type | Structure |
|---|---|---|---|
| Nanchangmycin-SNAC | Thioesterase | SNAC Polyketide |
|
| Di-ketide-SNAC | Thioesterase | SNAC Polyketide |
|
| Pimaricin-linear-analogue-synthetic | Thioesterase | SNAC Polyketide Macrolide |
|
| N-acetoacetyl-glycyl-SNAC | Dieckmann_Cyclase | SNAC |
|