| Title : (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]tr iazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Edmondson_2006_J.Med.Chem_49_3614 |
| Author(s) : Edmondson SD , Mastracchio A , Mathvink RJ , He J , Harper B , Park YJ , Beconi M , Di Salvo J , Eiermann GJ , He H , Leiting B , Leone JF , Levorse DA , Lyons K , Patel RA , Patel SB , Petrov A , Scapin G , Shang J , Roy RS , Smith A , Wu JK , Xu S , Zhu B , Thornberry NA , Weber AE |
| Ref : Journal of Medicinal Chemistry , 49 :3614 , 2006 |
| Abstract : |
| PubMedSearch : Edmondson_2006_J.Med.Chem_49_3614 |
| PubMedID: 16759103 |
| Gene_locus related to this paper: human-DPP4 |
| Title : (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)- yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Kim_2005_J.Med.Chem_48_141 |
| Author(s) : Kim D , Wang L , Beconi M , Eiermann GJ , Fisher MH , He H , Hickey GJ , Kowalchick JE , Leiting B , Lyons K , Marsilio F , McCann ME , Patel RA , Petrov A , Scapin G , Patel SB , Roy RS , Wu JK , Wyvratt MJ , Zhang BB , Zhu L , Thornberry NA , Weber AE |
| Ref : Journal of Medicinal Chemistry , 48 :141 , 2005 |
| Abstract : |
| PubMedSearch : Kim_2005_J.Med.Chem_48_141 |
| PubMedID: 15634008 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Potent and selective proline derived dipeptidyl peptidase IV inhibitors - Edmondson_2004_Bioorg.Med.Chem.Lett_14_5151 |
| Author(s) : Edmondson SD , Mastracchio A , Beconi M , Colwell LF, Jr. , Habulihaz B , He H , Kumar S , Leiting B , Lyons KA , Mao A , Marsilio F , Patel RA , Wu JK , Zhu L , Thornberry NA , Weber AE , Parmee ER |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :5151 , 2004 |
| Abstract : |
| PubMedSearch : Edmondson_2004_Bioorg.Med.Chem.Lett_14_5151 |
| PubMedID: 15380217 |