Title : (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]tr iazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Edmondson_2006_J.Med.Chem_49_3614 |
Author(s) : Edmondson SD , Mastracchio A , Mathvink RJ , He J , Harper B , Park YJ , Beconi M , Di Salvo J , Eiermann GJ , He H , Leiting B , Leone JF , Levorse DA , Lyons K , Patel RA , Patel SB , Petrov A , Scapin G , Shang J , Roy RS , Smith A , Wu JK , Xu S , Zhu B , Thornberry NA , Weber AE |
Ref : Journal of Medicinal Chemistry , 49 :3614 , 2006 |
Abstract : |
PubMedSearch : Edmondson_2006_J.Med.Chem_49_3614 |
PubMedID: 16759103 |
Gene_locus related to this paper: human-DPP4 |
Title : Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors - Xu_2006_Bioorg.Med.Chem.Lett_16_5373 |
Author(s) : Xu J , Wei L , Mathvink RJ , Edmondson SD , Eiermann GJ , He H , Leone JF , Leiting B , Lyons KA , Marsilio F , Patel RA , Patel SB , Petrov A , Scapin G , Wu JK , Thornberry NA , Weber AE |
Ref : Bioorganic & Medicinal Chemistry Lett , 16 :5373 , 2006 |
Abstract : |
PubMedSearch : Xu_2006_Bioorg.Med.Chem.Lett_16_5373 |
PubMedID: 16919457 |
Gene_locus related to this paper: human-DPP4 |
Title : Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors - Xu_2006_Bioorg.Med.Chem.Lett_16_1346 |
Author(s) : Xu J , Wei L , Mathvink R , Edmondson SD , Mastracchio A , Eiermann GJ , He H , Leone JF , Leiting B , Lyons KA , Marsilio F , Patel RA , Petrov A , Wu JK , Thornberry NA , Weber AE |
Ref : Bioorganic & Medicinal Chemistry Lett , 16 :1346 , 2006 |
Abstract : |
PubMedSearch : Xu_2006_Bioorg.Med.Chem.Lett_16_1346 |
PubMedID: 16332437 |
Title : Discovery of potent and selective orally bioavailable beta-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors - Edmondson_2005_Bioorg.Med.Chem.Lett_15_3048 |
Author(s) : Edmondson SD , Mastracchio A , Duffy JL , Eiermann GJ , He H , Ita I , Leiting B , Leone JF , Lyons KA , Makarewicz AM , Patel RA , Petrov A , Wu JK , Thornberry NA , Weber AE |
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :3048 , 2005 |
Abstract : |
PubMedSearch : Edmondson_2005_Bioorg.Med.Chem.Lett_15_3048 |
PubMedID: 15908206 |