| Title : Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium\/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors - Komloova_2013_Bioorg.Med.Chem.Lett_23_6663 |
| Author(s) : Komloova M , Horova A , Hrabinova M , Jun D , Dolezal M , Vinsova J , Kuca K , Musilek K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :6663 , 2013 |
| Abstract : |
| PubMedSearch : Komloova_2013_Bioorg.Med.Chem.Lett_23_6663 |
| PubMedID: 24220173 |
| Title : Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment - Musilek_2011_Eur.J.Med.Chem_46_811 |
| Author(s) : Musilek K , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Nachon F , Dolezal M , Kuca K |
| Ref : Eur Journal of Medicinal Chemistry , 46 :811 , 2011 |
| Abstract : |
| PubMedSearch : Musilek_2011_Eur.J.Med.Chem_46_811 |
| PubMedID: 21236521 |
| Title : The preparation, in vitro screening and molecular docking of symmetrical bisquaternary cholinesterase inhibitors containing a but-(2E)-en-1,4-diyl connecting linkage - Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| Author(s) : Musilek K , Pavlikova R , Marek J , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Dolezal M , Gunn-Moore F , Kuca K |
| Ref : J Enzyme Inhib Med Chem , 26 :245 , 2011 |
| Abstract : |
| PubMedSearch : Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| PubMedID: 21406034 |
| Title : Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking - Musilek_2011_Bioorg.Med.Chem_19_754 |
| Author(s) : Musilek K , Komloova M , Holas O , Horova A , Pohanka M , Gunn-Moore F , Dohnal V , Dolezal M , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry , 19 :754 , 2011 |
| Abstract : |
| PubMedSearch : Musilek_2011_Bioorg.Med.Chem_19_754 |
| PubMedID: 21215642 |
| Title : Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides - Musilek_2011_Med.Res.Rev_31_548 |
| Author(s) : Musilek K , Dolezal M , Gunn-Moore F , Kuca K |
| Ref : Med Res Rev , 31 :548 , 2011 |
| Abstract : |
| PubMedSearch : Musilek_2011_Med.Res.Rev_31_548 |
| PubMedID: 20027669 |
| Title : Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications - Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| Author(s) : Musilek K , Komloova M , Zavadova V , Holas O , Hrabinova M , Pohanka M , Dohnal V , Nachon F , Dolezal M , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1763 , 2010 |
| Abstract : |
| PubMedSearch : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| PubMedID: 20138518 |
| Title : Structure-activity relationship of quaternary acetylcholinesterase inhibitors - outlook for early myasthenia gravis treatment - Komloova_2010_Curr.Med.Chem_17_1810 |
| Author(s) : Komloova M , Musilek K , Dolezal M , Gunn-Moore F , Kuca K |
| Ref : Curr Med Chem , 17 :1810 , 2010 |
| Abstract : |
| PubMedSearch : Komloova_2010_Curr.Med.Chem_17_1810 |
| PubMedID: 20345342 |
| Title : RP-HPLC determination of the lipophilicity of bispyridinium reactivators of acetylcholinesterase bearing a but-2-ene connecting linker - Musilek_2008_Anal.Bioanal.Chem_391_367 |
| Author(s) : Musilek K , Jampilek J , Dohnal J , Jun D , Gunn-Moore F , Dolezal M , Kuca K |
| Ref : Anal Bioanal Chem , 391 :367 , 2008 |
| Abstract : |
| PubMedSearch : Musilek_2008_Anal.Bioanal.Chem_391_367 |
| PubMedID: 18369602 |
| Title : Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase - Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Opletalova V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 23 :70 , 2008 |
| Abstract : |
| PubMedSearch : Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| PubMedID: 18341256 |
| Title : Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 22 :425 , 2007 |
| Abstract : |
| PubMedSearch : Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| PubMedID: 17847708 |
| Title : Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase - Musilek_2007_Bioorg.Med.Chem_15_6733 |
| Author(s) : Musilek K , Holas O , Jun D , Dohnal V , Gunn-Moore F , Opletalova V , Dolezal M , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry , 15 :6733 , 2007 |
| Abstract : |
| PubMedSearch : Musilek_2007_Bioorg.Med.Chem_15_6733 |
| PubMedID: 17764957 |
| Title : Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Opletalova V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :3172 , 2007 |
| Abstract : |
| PubMedSearch : Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| PubMedID: 17383875 |
| Title : [Synthesis of reactivators of phosphorylated acetylcholinesterase of bis-pyridiniumdialdoxime type with a 3-oxapentane connecting chain and their testing in vitro on a model of the enzyme inhibited by chlorpyrifos and methylchlorpyrifos] - Musilek_2006_Ceska.Slov.Farm_55_115 |
| Author(s) : Musilek K , Kuca K , Jun D , Dohnal V , Kim TH , Jung YS , Dolezal M |
| Ref : Ceska a Slovenska Farmacie , 55 :115 , 2006 |
| Abstract : |
| PubMedSearch : Musilek_2006_Ceska.Slov.Farm_55_115 |
| PubMedID: 16838488 |
| Title : Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :5673 , 2006 |
| Abstract : |
| PubMedSearch : Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| PubMedID: 16934462 |
| Title : Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase - Musilek_2006_Bioorg.Med.Chem.Lett_16_622 |
| Author(s) : Musilek K , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :622 , 2006 |
| Abstract : |
| PubMedSearch : Musilek_2006_Bioorg.Med.Chem.Lett_16_622 |
| PubMedID: 16288867 |
| Title : Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase - Musilek_2005_J.Enzyme.Inhib.Med.Chem_20_409 |
| Author(s) : Musilek K , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 20 :409 , 2005 |
| Abstract : |
| PubMedSearch : Musilek_2005_J.Enzyme.Inhib.Med.Chem_20_409 |
| PubMedID: 16335048 |