| Title : Leveraging multitargeting BChE-MAO B inhibitors against microglia-related neuroinflammation: in vitro biological evaluation, structure-activity relationships, drug-like properties, and X-ray crystal complexes - Rullo_2026_Eur.J.Med.Chem_316_118961 |
| Author(s) : Rullo M , La Spada G , Brazzolotto X , Marchese S , El Idrissi IG , Miciaccia M , Colella M , Brea JM , Macchia E , Loza MI , Gottinger A , Scilimati A , Perrone MG , Stefanachi A , Binda C , Leonetti F , Pisani L |
| Ref : European Journal of Medicinal Chemistry , :118961 , 2026 |
| Abstract : |
| PubMedSearch : Rullo_2026_Eur.J.Med.Chem_316_118961 |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Glucosylpolyphenols as Inhibitors of Abeta-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease - de Matos_2020_J.Med.Chem_63_11663 |
| Author(s) : de Matos AM , Blazquez-Sanchez MT , Bento-Oliveira A , de Almeida RFM , Nunes R , Lopes PEM , Machuqueiro M , Cristovao JS , Gomes CM , Souza CS , El Idrissi IG , Colabufo NA , Diniz A , Marcelo F , Oliveira MC , Lopez O , Fernandez-Bolanos JG , Datwyler P , Ernst B , Ning K , Garwood C , Chen B , Rauter AP |
| Ref : Journal of Medicinal Chemistry , 63 :11663 , 2020 |
| Abstract : |
| PubMedSearch : de Matos_2020_J.Med.Chem_63_11663 |
| PubMedID: 32959649 |