| Title : Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE\/BChE selectivity switch and drug-like characterization - La Spada_2024_Eur.J.Med.Chem_274_116511 |
| Author(s) : La Spada G , Miniero DV , Rullo M , Cipolloni M , Delre P , Colliva C , Colella M , Leonetti F , Liuzzi GM , Mangiatordi GF , Giacche N , Pisani L |
| Ref : Eur Journal of Medicinal Chemistry , 274 :116511 , 2024 |
| Abstract : |
| PubMedSearch : La Spada_2024_Eur.J.Med.Chem_274_116511 |
| PubMedID: 38820854 |
| Title : A twenty-year journey exploring coumarin-based derivatives as bioactive molecules - Pisani_2022_Front.Chem_10_1002547 |
| Author(s) : Pisani L , Catto M , Muncipinto G , Nicolotti O , Carrieri A , Rullo M , Stefanachi A , Leonetti F , Altomare CD |
| Ref : Front Chem , 10 :1002547 , 2022 |
| Abstract : |
| PubMedSearch : Pisani_2022_Front.Chem_10_1002547 |
| PubMedID: 36300022 |
| Title : Angiopoietin-Like Protein 4 Overexpression in Visceral Adipose Tissue from Obese Subjects with Impaired Glucose Metabolism and Relationship with Lipoprotein Lipase - Barchetta_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Barchetta I , Chiappetta C , Ceccarelli V , Cimini FA , Bertoccini L , Gaggini M , Cristofano CD , Silecchia G , Lenzi A , Leonetti F , Baroni MG , Gastaldelli A , Cavallo MG |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : |
| PubMedSearch : Barchetta_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 33003532 |
| Title : Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds - Stefanachi_2018_Molecules_23_ |
| Author(s) : Stefanachi A , Leonetti F , Pisani L , Catto M , Carotti A |
| Ref : Molecules , 23 : , 2018 |
| Abstract : |
| PubMedSearch : Stefanachi_2018_Molecules_23_ |
| PubMedID: 29382051 |
| Title : Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors - Pau_2015_ChemMedChem_10_1054 |
| Author(s) : Pau A , Catto M , Pinna G , Frau S , Murineddu G , Asproni B , Curzu MM , Pisani L , Leonetti F , Loza MI , Brea J , Pinna GA , Carotti A |
| Ref : ChemMedChem , 10 :1054 , 2015 |
| Abstract : |
| PubMedSearch : Pau_2015_ChemMedChem_10_1054 |
| PubMedID: 25924828 |
| Title : Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase - Catto_2013_Bioorg.Med.Chem_21_146 |
| Author(s) : Catto M , Pisani L , Leonetti F , Nicolotti O , Pesce P , Stefanachi A , Cellamare S , Carotti A |
| Ref : Bioorganic & Medicinal Chemistry , 21 :146 , 2013 |
| Abstract : |
| PubMedSearch : Catto_2013_Bioorg.Med.Chem_21_146 |
| PubMedID: 23199476 |
| Title : Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases - Pisani_2011_Curr.Med.Chem_18_4568 |
| Author(s) : Pisani L , Catto M , Leonetti F , Nicolotti O , Stefanachi A , Campagna F , Carotti A |
| Ref : Curr Med Chem , 18 :4568 , 2011 |
| Abstract : |
| PubMedSearch : Pisani_2011_Curr.Med.Chem_18_4568 |
| PubMedID: 21864289 |
| Title : Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity - Conejo-Garcia_2011_J.Med.Chem_54_2627 |
| Author(s) : Conejo-Garcia A , Pisani L , Nunez Mdel C , Catto M , Nicolotti O , Leonetti F , Campos JM , Gallo MA , Espinosa A , Carotti A |
| Ref : Journal of Medicinal Chemistry , 54 :2627 , 2011 |
| Abstract : |
| PubMedSearch : Conejo-Garcia_2011_J.Med.Chem_54_2627 |
| PubMedID: 21417225 |
| Title : Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors - Pisani_2010_ChemMedChem_5_1616 |
| Author(s) : Pisani L , Catto M , Giangreco I , Leonetti F , Nicolotti O , Stefanachi A , Cellamare S , Carotti A |
| Ref : ChemMedChem , 5 :1616 , 2010 |
| Abstract : |
| PubMedSearch : Pisani_2010_ChemMedChem_5_1616 |
| PubMedID: 20677317 |
| Title : Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors - Leonetti_2008_Bioorg.Med.Chem_16_7450 |
| Author(s) : Leonetti F , Catto M , Nicolotti O , Pisani L , Cappa A , Stefanachi A , Carotti A |
| Ref : Bioorganic & Medicinal Chemistry , 16 :7450 , 2008 |
| Abstract : |
| PubMedSearch : Leonetti_2008_Bioorg.Med.Chem_16_7450 |
| PubMedID: 18585045 |
| Title : Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase - Bruhlmann_2001_J.Med.Chem_44_3195 |
| Author(s) : Bruhlmann C , Ooms F , Carrupt PA , Testa B , Catto M , Leonetti F , Altomare CD , Carotti A |
| Ref : Journal of Medicinal Chemistry , 44 :3195 , 2001 |
| Abstract : |
| PubMedSearch : Bruhlmann_2001_J.Med.Chem_44_3195 |
| PubMedID: 11543689 |