Perrone MG

Title : Leveraging multitargeting BChE-MAO B inhibitors against microglia-related neuroinflammation: in vitro biological evaluation, structure-activity relationships, drug-like properties, and X-ray crystal complexes - Rullo_2026_Eur.J.Med.Chem_316_118961

Author(s) : Rullo M , La Spada G , Brazzolotto X , Marchese S , El Idrissi IG , Miciaccia M , Colella M , Brea JM , Macchia E , Loza MI , Gottinger A , Scilimati A , Perrone MG , Stefanachi A , Binda C , Leonetti F , Pisani L

Ref : European Journal of Medicinal Chemistry , :118961 , 2026

Abstract :

PubMedSearch : Rullo_2026_Eur.J.Med.Chem_316_118961

PubMedID:

Gene_locus related to this paper: human-BCHE

Title : A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists - Perrone_2006_Bioorg.Med.Chem_14_1207

Author(s) : Perrone MG , Santandrea E , Giorgio E , Bleve L , Scilimati A , Tortorella P

Ref : Bioorganic & Medicinal Chemistry , 14 :1207 , 2006

Abstract :

PubMedSearch : Perrone_2006_Bioorg.Med.Chem_14_1207

PubMedID: 16216512

Perrone MG

References (2)

1. Leveraging multitargeting BChE-MAO B inhibitors against microglia-related neuroinflammation: in vitro biological evaluation, structure-activity relationships, drug-like properties, and X-ray crystal complexes - Rullo_2026_Eur.J.Med.Chem_316_118961

2. A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists - Perrone_2006_Bioorg.Med.Chem_14_1207