| Title : Leveraging multitargeting BChE-MAO B inhibitors against microglia-related neuroinflammation: in vitro biological evaluation, structure-activity relationships, drug-like properties, and X-ray crystal complexes - Rullo_2026_Eur.J.Med.Chem_316_118961 |
| Author(s) : Rullo M , La Spada G , Brazzolotto X , Marchese S , El Idrissi IG , Miciaccia M , Colella M , Brea JM , Macchia E , Loza MI , Gottinger A , Scilimati A , Perrone MG , Stefanachi A , Binda C , Leonetti F , Pisani L |
| Ref : European Journal of Medicinal Chemistry , :118961 , 2026 |
| Abstract : |
| PubMedSearch : Rullo_2026_Eur.J.Med.Chem_316_118961 |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE\/BChE selectivity switch and drug-like characterization - La Spada_2024_Eur.J.Med.Chem_274_116511 |
| Author(s) : La Spada G , Miniero DV , Rullo M , Cipolloni M , Delre P , Colliva C , Colella M , Leonetti F , Liuzzi GM , Mangiatordi GF , Giacche N , Pisani L |
| Ref : Eur Journal of Medicinal Chemistry , 274 :116511 , 2024 |
| Abstract : |
| PubMedSearch : La Spada_2024_Eur.J.Med.Chem_274_116511 |
| PubMedID: 38820854 |
| Title : The role of microemulsions in lipase-catalyzed hydrolysis reactions - Lopez_2014_Biotechnol.Prog_30_360 |
| Author(s) : Lopez F , Cinelli G , Colella M , De Leonardis A , Palazzo G , Ambrosone L |
| Ref : Biotechnol Prog , 30 :360 , 2014 |
| Abstract : |
| PubMedSearch : Lopez_2014_Biotechnol.Prog_30_360 |
| PubMedID: 24585724 |