| Title : Release of protein-bound nerve agents by excess fluoride from whole blood: GC-MS\/MS method development, validation, and application to a real-life denatured blood sample - Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693 |
| Author(s) : Koller M , Thiermann H , Worek F , Wille T |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 1179 :122693 , 2021 |
| Abstract : |
| PubMedSearch : Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693 |
| PubMedID: 34171608 |
| Title : Post-VX exposure treatment of rats with engineered phosphotriesterases - Stigler_2021_Arch.Toxicol__ |
| Author(s) : Stigler L , Kohler A , Koller M , Job L , Escher B , Potschka H , Thiermann H , Skerra A , Worek F , Wille T |
| Ref : Archives of Toxicology , : , 2021 |
| Abstract : |
| PubMedSearch : Stigler_2021_Arch.Toxicol__ |
| PubMedID: 34962578 |
| Title : In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase - Worek_2020_Molecules_25_ |
| Author(s) : Worek F , Thiermann H , Koller M , Wille T |
| Ref : Molecules , 25 : , 2020 |
| Abstract : |
| PubMedSearch : Worek_2020_Molecules_25_ |
| PubMedID: 32630769 |
| Title : A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making - Amend_2020_Arch.Toxicol__ |
| Author(s) : Amend N , Langgartner J , Siegert M , Kranawetvogl T , Koller M , John H , Pflugler C , Mogele-Schmid C , Worek F , Thiermann H , Wille T |
| Ref : Archives of Toxicology , : , 2020 |
| Abstract : |
| PubMedSearch : Amend_2020_Arch.Toxicol__ |
| PubMedID: 32303803 |
| Title : Fatal sarin poisoning in Syria 2013: forensic verification within an international laboratory network - John_2018_Forensic.Toxicol_36_61 |
| Author(s) : John H , van der Schans MJ , Koller M , Spruit HET , Worek F , Thiermann H , Noort D |
| Ref : Forensic Toxicol , 36 :61 , 2018 |
| Abstract : |
| PubMedSearch : John_2018_Forensic.Toxicol_36_61 |
| PubMedID: 29367863 |
| Title : Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics - Worek_2016_Toxicology_350-352_25 |
| Author(s) : Worek F , Koller M , Thiermann H , Wille T |
| Ref : Toxicology , 350-352 :25 , 2016 |
| Abstract : |
| PubMedSearch : Worek_2016_Toxicology_350-352_25 |
| PubMedID: 27153754 |
| Title : Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection - Wille_2016_Toxicol.Lett_258_198 |
| Author(s) : Wille T , Neumaier K , Koller M , Ehinger C , Aggarwal N , Ashani Y , Goldsmith M , Sussman JL , Tawfik DS , Thiermann H , Worek F |
| Ref : Toxicol Lett , 258 :198 , 2016 |
| Abstract : |
| PubMedSearch : Wille_2016_Toxicol.Lett_258_198 |
| PubMedID: 27397758 |
| Title : Application of a dynamic in vitro model with real-time determination of acetylcholinesterase activity for the investigation of tabun analogues and oximes - Worek_2015_Toxicol.In.Vitro_30_514 |
| Author(s) : Worek F , Herkert NM , Koller M , Thiermann H , Wille T |
| Ref : Toxicol In Vitro , 30 :514 , 2015 |
| Abstract : |
| PubMedSearch : Worek_2015_Toxicol.In.Vitro_30_514 |
| PubMedID: 26368669 |
| Title : Reactions of methylphosphonic difluoride with human acetylcholinesterase and oximes - Possible therapeutic implications - Worek_2014_Toxicol.Lett_231_92 |
| Author(s) : Worek F , Elsinghorst P , Koller M , Thiermann H |
| Ref : Toxicol Lett , 231 :92 , 2014 |
| Abstract : |
| PubMedSearch : Worek_2014_Toxicol.Lett_231_92 |
| PubMedID: 25240274 |
| Title : Structural requirements for effective oximes - Evaluation of kinetic in vitro data with phosphylated human AChE and structurally different oximes - Worek_2013_Chem.Biol.Interact_203_125 |
| Author(s) : Worek F , Wille T , Koller M , Thiermann H |
| Ref : Chemico-Biological Interactions , 203 :125 , 2013 |
| Abstract : |
| PubMedSearch : Worek_2013_Chem.Biol.Interact_203_125 |
| PubMedID: 22827894 |
| Title : Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships - Worek_2012_Biochem.Pharmacol_83_1700 |
| Author(s) : Worek F , Wille T , Koller M , Thiermann H |
| Ref : Biochemical Pharmacology , 83 :1700 , 2012 |
| Abstract : |
| PubMedSearch : Worek_2012_Biochem.Pharmacol_83_1700 |
| PubMedID: 22649796 |
| Title : Purity of antidotal oxime HI-6 DMS as an active pharmaceutical ingredient for auto-injectors and infusions - Bogan_2012_Drug.Test.Anal_4_199 |
| Author(s) : Bogan R , Koller M , Klaubert B |
| Ref : Drug Test Anal , 4 :199 , 2012 |
| Abstract : |
| PubMedSearch : Bogan_2012_Drug.Test.Anal_4_199 |
| PubMedID: 22362586 |
| Title : Photostability of antidotal oxime HI-6, impact on drug development - Bogan_2012_Drug.Test.Anal_4_208 |
| Author(s) : Bogan R , Worek F , Koller M , Klaubert B |
| Ref : Drug Test Anal , 4 :208 , 2012 |
| Abstract : |
| PubMedSearch : Bogan_2012_Drug.Test.Anal_4_208 |
| PubMedID: 22359386 |
| Title : In vitro detoxification of cyclosarin (GF) by modified cyclodextrins - Muller_2011_Toxicol.Lett_200_53 |
| Author(s) : Muller S , Koller M , Le Provost R , Lafont O , Estour F , Wille T , Thiermann H , Worek F , Reiter G |
| Ref : Toxicol Lett , 200 :53 , 2011 |
| Abstract : |
| PubMedSearch : Muller_2011_Toxicol.Lett_200_53 |
| PubMedID: 21035528 |
| Title : GC-MS and LC-MS analysis of nerve agents in body fluids: intra-laboratory verification test using spiked plasma and urine samples - Koller_2010_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_878_1226 |
| Author(s) : Koller M , Becker C , Thiermann H , Worek F |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 878 :1226 , 2010 |
| Abstract : |
| PubMedSearch : Koller_2010_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_878_1226 |
| PubMedID: 20061191 |
| Title : Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship? - Aurbek_2010_Chem.Biol.Interact_187_215 |
| Author(s) : Aurbek N , Herkert NM , Koller M , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 187 :215 , 2010 |
| Abstract : |
| PubMedSearch : Aurbek_2010_Chem.Biol.Interact_187_215 |
| PubMedID: 20105433 |
| Title : Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design - Melzer_2009_J.Am.Chem.Soc_131_17226 |
| Author(s) : Melzer M , Chen JC , Heidenreich A , Gab J , Koller M , Kehe K , Blum MM |
| Ref : J Am Chem Soc , 131 :17226 , 2009 |
| Abstract : |
| PubMedSearch : Melzer_2009_J.Am.Chem.Soc_131_17226 |
| PubMedID: 19894712 |
| Title : Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study - Worek_2009_Toxicol.Lett_187_119 |
| Author(s) : Worek F , Herkert NM , Koller M , Aurbek N , Thiermann H |
| Ref : Toxicol Lett , 187 :119 , 2009 |
| Abstract : |
| PubMedSearch : Worek_2009_Toxicol.Lett_187_119 |
| PubMedID: 19429253 |
| Title : Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates - Worek_2007_Biochem.Pharmacol_73_1807 |
| Author(s) : Worek F , Aurbek N , Koller M , Becker C , Eyer P , Thiermann H |
| Ref : Biochemical Pharmacology , 73 :1807 , 2007 |
| Abstract : |
| PubMedSearch : Worek_2007_Biochem.Pharmacol_73_1807 |
| PubMedID: 17382909 |
| Title : Diagnostic aspects of organophosphate poisoning - Worek_2005_Toxicology_214_182 |
| Author(s) : Worek F , Koller M , Thiermann H , Szinicz L |
| Ref : Toxicology , 214 :182 , 2005 |
| Abstract : |
| PubMedSearch : Worek_2005_Toxicology_214_182 |
| PubMedID: 16051411 |