Facincani AP

References (2)

Title : Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp. aurantifolii - Moreira_2010_BMC.Genomics_11_238
Author(s) : Moreira LM , Almeida NF, Jr. , Potnis N , Digiampietri LA , Adi SS , Bortolossi JC , da Silva AC , da Silva AM , de Moraes FE , de Oliveira JC , de Souza RF , Facincani AP , Ferraz AL , Ferro MI , Furlan LR , Gimenez DF , Jones JB , Kitajima EW , Laia ML , Leite RP, Jr. , Nishiyama MY , Rodrigues Neto J , Nociti LA , Norman DJ , Ostroski EH , Pereira HA, Jr. , Staskawicz BJ , Tezza RI , Ferro JA , Vinatzer BA , Setubal JC
Ref : BMC Genomics , 11 :238 , 2010
Abstract : BACKGROUND: Citrus canker is a disease that has severe economic impact on the citrus industry worldwide. There are three types of canker, called A, B, and C. The three types have different phenotypes and affect different citrus species. The causative agent for type A is Xanthomonas citri subsp. citri, whose genome sequence was made available in 2002. Xanthomonas fuscans subsp. aurantifolii strain B causes canker B and Xanthomonas fuscans subsp. aurantifolii strain C causes canker C.
RESULTS: We have sequenced the genomes of strains B and C to draft status. We have compared their genomic content to X. citri subsp. citri and to other Xanthomonas genomes, with special emphasis on type III secreted effector repertoires. In addition to pthA, already known to be present in all three citrus canker strains, two additional effector genes, xopE3 and xopAI, are also present in all three strains and are both located on the same putative genomic island. These two effector genes, along with one other effector-like gene in the same region, are thus good candidates for being pathogenicity factors on citrus. Numerous gene content differences also exist between the three cankers strains, which can be correlated with their different virulence and host range. Particular attention was placed on the analysis of genes involved in biofilm formation and quorum sensing, type IV secretion, flagellum synthesis and motility, lipopolysacharide synthesis, and on the gene xacPNP, which codes for a natriuretic protein. CONCLUSION: We have uncovered numerous commonalities and differences in gene content between the genomes of the pathogenic agents causing citrus canker A, B, and C and other Xanthomonas genomes. Molecular genetics can now be employed to determine the role of these genes in plant-microbe interactions. The gained knowledge will be instrumental for improving citrus canker control.
ESTHER : Moreira_2010_BMC.Genomics_11_238
PubMedSearch : Moreira_2010_BMC.Genomics_11_238
PubMedID: 20388224
Gene_locus related to this paper: xanax-CATD , xanax-ENTF2 , xanax-estA1 , xanax-GAA , xanax-PTRB , xanax-XAC0198 , xanax-XAC0515 , xanax-XAC0591 , xanax-XAC0619 , xanax-XAC0628 , xanax-XAC0736 , xanax-XAC0753 , xanax-XAC0805 , xanax-XAC1213 , xanax-XAC1713 , xanax-XAC1752 , xanax-XAC2393 , xanax-XAC2532 , xanax-XAC2541 , xanax-XAC2987 , xanax-XAC3315 , xanax-XAC3371 , xanax-XAC4046 , xanax-XAC4055 , xanax-XAC4106 , xanax-XYNB , xanc5-q3bqi2 , xanca-impep , xanca-XCC1105 , xanca-XCC2566 , xanca-XCC2722 , xanor-acvB , xanor-metx , 9xant-a0a0g8v5k2

Title : The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis - Simpson_2000_Nature_406_151
Author(s) : Simpson AJ , Reinach FC , Arruda P , Abreu FA , Acencio M , Alvarenga R , Alves LM , Araya JE , Baia GS , Baptista CS , Barros MH , Bonaccorsi ED , Bordin S , Bove JM , Briones MR , Bueno MR , Camargo AA , Camargo LE , Carraro DM , Carrer H , Colauto NB , Colombo C , Costa FF , Costa MC , Costa-Neto CM , Coutinho LL , Cristofani M , Dias-Neto E , Docena C , El-Dorry H , Facincani AP , Ferreira AJ , Ferreira VC , Ferro JA , Fraga JS , Franca SC , Franco MC , Frohme M , Furlan LR , Garnier M , Goldman GH , Goldman MH , Gomes SL , Gruber A , Ho PL , Hoheisel JD , Junqueira ML , Kemper EL , Kitajima JP , Krieger JE , Kuramae EE , Laigret F , Lambais MR , Leite LC , Lemos EG , Lemos MV , Lopes SA , Lopes CR , Machado JA , Machado MA , Madeira AM , Madeira HM , Marino CL , Marques MV , Martins EA , Martins EM , Matsukuma AY , Menck CF , Miracca EC , Miyaki CY , Monteriro-Vitorello CB , Moon DH , Nagai MA , Nascimento AL , Netto LE , Nhani A, Jr. , Nobrega FG , Nunes LR , Oliveira MA , de Oliveira MC , de Oliveira RC , Palmieri DA , Paris A , Peixoto BR , Pereira GA , Pereira HA, Jr. , Pesquero JB , Quaggio RB , Roberto PG , Rodrigues V , de MRAJ , de Rosa VE, Jr. , de Sa RG , Santelli RV , Sawasaki HE , da Silva AC , da Silva AM , da Silva FR , da Silva WA, Jr. , da Silveira JF , Silvestri ML , Siqueira WJ , de Souza AA , de Souza AP , Terenzi MF , Truffi D , Tsai SM , Tsuhako MH , Vallada H , Van Sluys MA , Verjovski-Almeida S , Vettore AL , Zago MA , Zatz M , Meidanis J , Setubal JC
Ref : Nature , 406 :151 , 2000
Abstract : Xylella fastidiosa is a fastidious, xylem-limited bacterium that causes a range of economically important plant diseases. Here we report the complete genome sequence of X. fastidiosa clone 9a5c, which causes citrus variegated chlorosis--a serious disease of orange trees. The genome comprises a 52.7% GC-rich 2,679,305-base-pair (bp) circular chromosome and two plasmids of 51,158 bp and 1,285 bp. We can assign putative functions to 47% of the 2,904 predicted coding regions. Efficient metabolic functions are predicted, with sugars as the principal energy and carbon source, supporting existence in the nutrient-poor xylem sap. The mechanisms associated with pathogenicity and virulence involve toxins, antibiotics and ion sequestration systems, as well as bacterium-bacterium and bacterium-host interactions mediated by a range of proteins. Orthologues of some of these proteins have only been identified in animal and human pathogens; their presence in X. fastidiosa indicates that the molecular basis for bacterial pathogenicity is both conserved and independent of host. At least 83 genes are bacteriophage-derived and include virulence-associated genes from other bacteria, providing direct evidence of phage-mediated horizontal gene transfer.
ESTHER : Simpson_2000_Nature_406_151
PubMedSearch : Simpson_2000_Nature_406_151
PubMedID: 10910347
Gene_locus related to this paper: xylfa-ACVB , xylfa-cxest , xylfa-metx , xylfa-PD2024 , xylfa-pip , xylfa-q9pdj5 , xylfa-XF0015 , xylfa-XF0357 , xylfa-XF0358 , xylfa-XF0754 , xylfa-XF0863 , xylfa-XF0992 , xylfa-XF1029 , xylfa-XF1181 , xylfa-XF1253 , xylfa-XF1282 , xylfa-XF1356 , xylfa-XF1479 , xylfa-XF1743 , xylfa-XF1745 , xylfa-XF1750 , xylfa-XF1829 , xylfa-XF1965 , xylfa-XF2151 , xylfa-XF2260 , xylfa-XF2330 , xylfa-XF2551 , xylfa-XFA0032