| Title : Synthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor - |
| Author(s) : Kennedy JP , Bridges TM , Gentry PR , Brogan JT , Kane AS , Jones CK , Brady AE , Shirey JK , Conn PJ , Lindsley CW |
| Ref : ChemMedChem , 4 :1600 , 2009 |
| PubMedID: 19705385 |
| Title : Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins - Bridges_2009_J.Med.Chem_52_3445 |
| Author(s) : Bridges TM , Marlo JE , Niswender CM , Jones CK , Jadhav SB , Gentry PR , Plumley HC , Weaver CD , Conn PJ , Lindsley CW |
| Ref : Journal of Medicinal Chemistry , 52 :3445 , 2009 |
| Abstract : Bridges_2009_J.Med.Chem_52_3445 |
| ESTHER : Bridges_2009_J.Med.Chem_52_3445 |
| PubMedSearch : Bridges_2009_J.Med.Chem_52_3445 |
| PubMedID: 19438238 |
| Title : Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats - Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| Author(s) : Brady AE , Jones CK , Bridges TM , Kennedy JP , Thompson AD , Heiman JU , Breininger ML , Gentry PR , Yin H , Jadhav SB , Shirey JK , Conn PJ , Lindsley CW |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 327 :941 , 2008 |
| Abstract : Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| ESTHER : Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| PubMedSearch : Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| PubMedID: 18772318 |
| Title : Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties - Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| Author(s) : Bridges TM , Brady AE , Kennedy JP , Daniels RN , Miller NR , Kim K , Breininger ML , Gentry PR , Brogan JT , Jones CK , Conn PJ , Lindsley CW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5439 , 2008 |
| Abstract : Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| ESTHER : Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| PubMedSearch : Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| PubMedID: 18805692 |