| Title : Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system - Lebois_2010_ACS.Chem.Neurosci_1_104 |
| Author(s) : LeBois EP , Bridges TM , Lewis LM , Dawson ES , Kane AS , Xiang Z , Jadhav SB , Yin H , Kennedy JP , Meiler J , Niswender CM , Jones CK , Conn PJ , Weaver CD , Lindsley CW |
| Ref : ACS Chem Neurosci , 1 :104 , 2010 |
| Abstract : Lebois_2010_ACS.Chem.Neurosci_1_104 |
| ESTHER : Lebois_2010_ACS.Chem.Neurosci_1_104 |
| PubMedSearch : Lebois_2010_ACS.Chem.Neurosci_1_104 |
| PubMedID: 21961051 |
| Title : Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probe - Weaver_2009_Curr.Top.Med.Chem_9_1217 |
| Author(s) : Weaver CD , Sheffler DJ , Lewis LM , Bridges TM , Williams R , Nalywajko NT , Kennedy JP , Mulder MM , Jadhav S , Aldrich LA , Jones CK , Marlo JE , Niswender CM , Mock MM , Zheng F , Conn PJ , Lindsley CW |
| Ref : Curr Top Med Chem , 9 :1217 , 2009 |
| Abstract : Weaver_2009_Curr.Top.Med.Chem_9_1217 |
| ESTHER : Weaver_2009_Curr.Top.Med.Chem_9_1217 |
| PubMedSearch : Weaver_2009_Curr.Top.Med.Chem_9_1217 |
| PubMedID: 19807667 |
| Title : A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning - Shirey_2009_J.Neurosci_29_14271 |
| Author(s) : Shirey JK , Brady AE , Jones PJ , Davis AA , Bridges TM , Kennedy JP , Jadhav SB , Menon UN , Xiang Z , Watson ML , Christian EP , Doherty JJ , Quirk MC , Snyder DH , Lah JJ , Levey AI , Nicolle MM , Lindsley CW , Conn PJ |
| Ref : Journal of Neuroscience , 29 :14271 , 2009 |
| Abstract : Shirey_2009_J.Neurosci_29_14271 |
| ESTHER : Shirey_2009_J.Neurosci_29_14271 |
| PubMedSearch : Shirey_2009_J.Neurosci_29_14271 |
| PubMedID: 19906975 |
| Title : Synthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor - |
| Author(s) : Kennedy JP , Bridges TM , Gentry PR , Brogan JT , Kane AS , Jones CK , Brady AE , Shirey JK , Conn PJ , Lindsley CW |
| Ref : ChemMedChem , 4 :1600 , 2009 |
| PubMedID: 19705385 |
| Title : Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats - Jones_2008_J.Neurosci_28_10422 |
| Author(s) : Jones CK , Brady AE , Davis AA , Xiang Z , Bubser M , Tantawy MN , Kane AS , Bridges TM , Kennedy JP , Bradley SR , Peterson TE , Ansari MS , Baldwin RM , Kessler RM , Deutch AY , Lah JJ , Levey AI , Lindsley CW , Conn PJ |
| Ref : Journal of Neuroscience , 28 :10422 , 2008 |
| Abstract : Jones_2008_J.Neurosci_28_10422 |
| ESTHER : Jones_2008_J.Neurosci_28_10422 |
| PubMedSearch : Jones_2008_J.Neurosci_28_10422 |
| PubMedID: 18842902 |
| Title : Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats - Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| Author(s) : Brady AE , Jones CK , Bridges TM , Kennedy JP , Thompson AD , Heiman JU , Breininger ML , Gentry PR , Yin H , Jadhav SB , Shirey JK , Conn PJ , Lindsley CW |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 327 :941 , 2008 |
| Abstract : Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| ESTHER : Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| PubMedSearch : Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| PubMedID: 18772318 |
| Title : Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties - Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| Author(s) : Bridges TM , Brady AE , Kennedy JP , Daniels RN , Miller NR , Kim K , Breininger ML , Gentry PR , Brogan JT , Jones CK , Conn PJ , Lindsley CW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5439 , 2008 |
| Abstract : Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| ESTHER : Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| PubMedSearch : Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| PubMedID: 18805692 |