Full name : Brady Ashley E
First name : Ashley E
Mail : Department of Pharmacology, Vanderbilt Program in Drug Discovery, Vanderbilt University Medical Center, Nashville, TN 37232-6600
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Country : USA
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Comment
| Title : Study of GPCR-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs - Brady_2011_Methods.Mol.Biol_746_347 |
| Author(s) : Brady AE , Chen Y , Limbird LE , Wang Q |
| Ref : Methods Mol Biol , 746 :347 , 2011 |
| Abstract : |
| PubMedSearch : Brady_2011_Methods.Mol.Biol_746_347 |
| PubMedID: 21607867 |
| Title : Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation - Davis_2010_ACS.Chem.Neurosci_1_542 |
| Author(s) : Davis AA , Heilman CJ , Brady AE , Miller NR , Fuerstenau-Sharp M , Hanson BJ , Lindsley CW , Conn PJ , Lah JJ , Levey AI |
| Ref : ACS Chem Neurosci , 1 :542 , 2010 |
| Abstract : |
| PubMedSearch : Davis_2010_ACS.Chem.Neurosci_1_542 |
| PubMedID: 20835371 |
| Title : Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity - Marlo_2009_Mol.Pharmacol_75_577 |
| Author(s) : Marlo JE , Niswender CM , Days EL , Bridges TM , Xiang Y , Rodriguez AL , Shirey JK , Brady AE , Nalywajko T , Luo Q , Austin CA , Williams MB , Kim K , Williams R , Orton D , Brown HA , Lindsley CW , Weaver CD , Conn PJ |
| Ref : Molecular Pharmacology , 75 :577 , 2009 |
| Abstract : |
| PubMedSearch : Marlo_2009_Mol.Pharmacol_75_577 |
| PubMedID: 19047481 |
| Title : A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning - Shirey_2009_J.Neurosci_29_14271 |
| Author(s) : Shirey JK , Brady AE , Jones PJ , Davis AA , Bridges TM , Kennedy JP , Jadhav SB , Menon UN , Xiang Z , Watson ML , Christian EP , Doherty JJ , Quirk MC , Snyder DH , Lah JJ , Levey AI , Nicolle MM , Lindsley CW , Conn PJ |
| Ref : Journal of Neuroscience , 29 :14271 , 2009 |
| Abstract : |
| PubMedSearch : Shirey_2009_J.Neurosci_29_14271 |
| PubMedID: 19906975 |
| Title : Synthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor - |
| Author(s) : Kennedy JP , Bridges TM , Gentry PR , Brogan JT , Kane AS , Jones CK , Brady AE , Shirey JK , Conn PJ , Lindsley CW |
| Ref : ChemMedChem , 4 :1600 , 2009 |
| PubMedID: 19705385 |
| Title : Synthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen - Miller_2008_Bioorg.Med.Chem.Lett_18_5443 |
| Author(s) : Miller NR , Daniels RN , Bridges TM , Brady AE , Conn PJ , Lindsley CW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5443 , 2008 |
| Abstract : |
| PubMedSearch : Miller_2008_Bioorg.Med.Chem.Lett_18_5443 |
| PubMedID: 18829311 |
| Title : Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats - Jones_2008_J.Neurosci_28_10422 |
| Author(s) : Jones CK , Brady AE , Davis AA , Xiang Z , Bubser M , Tantawy MN , Kane AS , Bridges TM , Kennedy JP , Bradley SR , Peterson TE , Ansari MS , Baldwin RM , Kessler RM , Deutch AY , Lah JJ , Levey AI , Lindsley CW , Conn PJ |
| Ref : Journal of Neuroscience , 28 :10422 , 2008 |
| Abstract : |
| PubMedSearch : Jones_2008_J.Neurosci_28_10422 |
| PubMedID: 18842902 |
| Title : An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission - Shirey_2008_Nat.Chem.Biol_4_42 |
| Author(s) : Shirey JK , Xiang Z , Orton D , Brady AE , Johnson KA , Williams R , Ayala JE , Rodriguez AL , Wess J , Weaver D , Niswender CM , Conn PJ |
| Ref : Nat Chemical Biology , 4 :42 , 2008 |
| Abstract : |
| PubMedSearch : Shirey_2008_Nat.Chem.Biol_4_42 |
| PubMedID: 18059262 |
| Title : Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats - Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| Author(s) : Brady AE , Jones CK , Bridges TM , Kennedy JP , Thompson AD , Heiman JU , Breininger ML , Gentry PR , Yin H , Jadhav SB , Shirey JK , Conn PJ , Lindsley CW |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 327 :941 , 2008 |
| Abstract : |
| PubMedSearch : Brady_2008_J.Pharmacol.Exp.Ther_327_941 |
| PubMedID: 18772318 |
| Title : Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties - Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| Author(s) : Bridges TM , Brady AE , Kennedy JP , Daniels RN , Miller NR , Kim K , Breininger ML , Gentry PR , Brogan JT , Jones CK , Conn PJ , Lindsley CW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5439 , 2008 |
| Abstract : |
| PubMedSearch : Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 |
| PubMedID: 18805692 |
| Title : Membrane trafficking of G protein-coupled receptors - Tan_2004_Annu.Rev.Pharmacol.Toxicol_44_559 |
| Author(s) : Tan CM , Brady AE , Nickols HH , Wang Q , Limbird LE |
| Ref : Annual Review of Pharmacology & Toxicology , 44 :559 , 2004 |
| Abstract : |
| PubMedSearch : Tan_2004_Annu.Rev.Pharmacol.Toxicol_44_559 |
| PubMedID: 14744258 |
| Title : Study of G-protein-coupled receptor-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs - Brady_2004_Methods.Mol.Biol_259_371 |
| Author(s) : Brady AE , Wang Q , Limbird LE |
| Ref : Methods Mol Biol , 259 :371 , 2004 |
| Abstract : |
| PubMedSearch : Brady_2004_Methods.Mol.Biol_259_371 |
| PubMedID: 15250505 |
| Title : G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction - Brady_2002_Cell.Signal_14_297 |
| Author(s) : Brady AE , Limbird LE |
| Ref : Cell Signal , 14 :297 , 2002 |
| Abstract : |
| PubMedSearch : Brady_2002_Cell.Signal_14_297 |
| PubMedID: 11858937 |