Title : Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair - Bolgi_2022_EMBO.Rep__e54136 |
Author(s) : Bolgi O , Silva-Garcia M , Ross B , Pilla E , Kari V , Killisch M , Spitzner M , Stark N , Lenz C , Weiss K , Donzelli L , Gorrell MD , Grade M , Riemer J , Urlaub H , Dobbelstein M , Huber R , Geiss-Friedlander R |
Ref : EMBO Rep , :e54136 , 2022 |
Abstract : |
PubMedSearch : Bolgi_2022_EMBO.Rep__e54136 |
PubMedID: 35912982 |
Gene_locus related to this paper: human-DPP8 , human-DPP9 |
Title : DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1\/IL-1 signaling - Harapas_2022_Sci.Immunol_7_eabi4611 |
Author(s) : Harapas CR , Robinson KS , Lay K , Wong J , Moreno Traspas R , Nabavizadeh N , Rass-Rothschild A , Boisson B , Drutman SB , Laohamonthonkul P , Bonner D , Xiong JR , Gorrell MD , Davidson S , Yu CH , Fleming MD , Gudera J , Stein J , Ben-Harosh M , Groopman E , Shimamura A , Tamary H , Kayserili H , Hatipoglu N , Casanova JL , Bernstein JA , Zhong FL , Masters SL , Reversade B |
Ref : Sci Immunol , 7 :eabi4611 , 2022 |
Abstract : |
PubMedSearch : Harapas_2022_Sci.Immunol_7_eabi4611 |
PubMedID: 36112693 |
Gene_locus related to this paper: human-DPP9 |
Title : DPP9: Comprehensive In Silico Analyses of Loss of Function Gene Variants and Associated Gene Expression Signatures in Human Hepatocellular Carcinoma - Huang_2021_Cancers.(Basel)_13_ |
Author(s) : Huang JC , Emran AA , Endaya JM , McCaughan GW , Gorrell MD , Zhang HE |
Ref : Cancers (Basel) , 13 : , 2021 |
Abstract : |
PubMedSearch : Huang_2021_Cancers.(Basel)_13_ |
PubMedID: 33915844 |
Title : A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2 - Xi_2020_Molecules_25_ |
Author(s) : Xi CR , Di Fazio A , Nadvi NA , Patel K , Xiang MSW , Zhang HE , Deshpande C , Low JKK , Wang XT , Chen Y , McMillan CLD , Isaacs A , Osborne B , Vieira de Ribeiro AJ , McCaughan GW , Mackay JP , Church WB , Gorrell MD |
Ref : Molecules , 25 : , 2020 |
Abstract : |
PubMedSearch : Xi_2020_Molecules_25_ |
PubMedID: 33218025 |
Title : Covid-19 and co-morbidities: a role for Dipeptidyl Peptidase 4 (DPP4) in disease severity? - Bassendine_2020_J.Diabetes__ |
Author(s) : Bassendine MF , Bridge SH , McCaughan GW , Gorrell MD |
Ref : J Diabetes , : , 2020 |
Abstract : |
PubMedSearch : Bassendine_2020_J.Diabetes__ |
PubMedID: 32394639 |
Title : Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair - Silva-Garcia_2020_Biorxiv__ |
Author(s) : Silva-Garcia M , Bolgi O , Ross B , Pilla E , Kari V , Killisch M , Stark N , Lenz C , Spitzner M , Gorrell MD , Grade M , Urlaub H , Dobbelstein M , Huber R , Geiss-Friedlander R |
Ref : Biorxiv , : , 2020 |
Abstract : |
PubMedSearch : Silva-Garcia_2020_Biorxiv__ |
PubMedID: |
Gene_locus related to this paper: human-DPP8 , human-DPP9 |
Title : Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity - Gall_2019_Sci.Rep_9_7292 |
Author(s) : Gall MG , Zhang HE , Lee Q , Jolly CJ , McCaughan GW , Cook A , Roediger B , Gorrell MD |
Ref : Sci Rep , 9 :7292 , 2019 |
Abstract : |
PubMedSearch : Gall_2019_Sci.Rep_9_7292 |
PubMedID: 31086209 |
Gene_locus related to this paper: human-DPP9 |
Title : The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury - Wang_2017_Immunol.Cell.Biol_95_443 |
Author(s) : Wang XM , Holz LE , Chowdhury S , Cordoba SP , Evans KA , Gall MG , Vieira de Ribeiro AJ , Zheng YZ , Levy MT , Yu DM , Yao TW , Polak N , Jolly CJ , Bertolino P , McCaughan GW , Gorrell MD |
Ref : Immunol Cell Biol , 95 :443 , 2017 |
Abstract : |
PubMedSearch : Wang_2017_Immunol.Cell.Biol_95_443 |
PubMedID: 27899813 |
Title : Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches - Wilson_2016_Biol.Chem_397_837 |
Author(s) : Wilson CH , Zhang HE , Gorrell MD , Abbott CA |
Ref : Biol Chem , 397 :837 , 2016 |
Abstract : |
PubMedSearch : Wilson_2016_Biol.Chem_397_837 |
PubMedID: 27410463 |
Gene_locus related to this paper: human-DPP9 |
Title : Neuropeptide Y is a physiological substrate of fibroblast activation protein: Enzyme kinetics in blood plasma and expression of Y2R and Y5R in human liver cirrhosis and hepatocellular carcinoma - Wong_2016_Peptides_75_80 |
Author(s) : Wong PF , Gall MG , Bachovchin WW , McCaughan GW , Keane FM , Gorrell MD |
Ref : Peptides , 75 :80 , 2016 |
Abstract : |
PubMedSearch : Wong_2016_Peptides_75_80 |
PubMedID: 26621486 |
Title : Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes - Chen_2016_Exp.Cell.Res_342_72 |
Author(s) : Chen Y , Gall MG , Zhang H , Keane FM , McCaughan GW , Yu DM , Gorrell MD |
Ref : Experimental Cell Research , 342 :72 , 2016 |
Abstract : |
PubMedSearch : Chen_2016_Exp.Cell.Res_342_72 |
PubMedID: 26930324 |
Gene_locus related to this paper: mouse-dpp9 |
Title : Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin - Zhang_2015_Biochim.Biophys.Acta_1853_470 |
Author(s) : Zhang H , Chen Y , Wadham C , McCaughan GW , Keane FM , Gorrell MD |
Ref : Biochimica & Biophysica Acta , 1853 :470 , 2015 |
Abstract : |
PubMedSearch : Zhang_2015_Biochim.Biophys.Acta_1853_470 |
PubMedID: 25486458 |
Title : Identification of novel dipeptidyl peptidase 9 substrates by two-dimensional differential in-gel electrophoresis - Zhang_2015_FEBS.J_282_3737 |
Author(s) : Zhang H , Maqsudi S , Rainczuk A , Duffield N , Lawrence J , Keane FM , Justa-Schuch D , Geiss-Friedlander R , Gorrell MD , Stephens AN |
Ref : Febs J , 282 :3737 , 2015 |
Abstract : |
PubMedSearch : Zhang_2015_FEBS.J_282_3737 |
PubMedID: 26175140 |
Title : A rare variant in human fibroblast activation protein associated with ER stress, loss of enzymatic function and loss of cell surface localisation - Osborne_2014_Biochim.Biophys.Acta_1844_1248 |
Author(s) : Osborne B , Yao TW , Wang XM , Chen Y , Kotan LD , Nadvi NA , Herdem M , McCaughan GW , Allen JD , Yu DM , Topaloglu AK , Gorrell MD |
Ref : Biochimica & Biophysica Acta , 1844 :1248 , 2014 |
Abstract : |
PubMedSearch : Osborne_2014_Biochim.Biophys.Acta_1844_1248 |
PubMedID: 24717288 |
Gene_locus related to this paper: human-FAP |
Title : Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver - Chowdhury_2013_World.J.Gastroenterol_19_2883 |
Author(s) : Chowdhury S , Chen Y , Yao TW , Ajami K , Wang XM , Popov Y , Schuppan D , Bertolino P , McCaughan GW , Yu DM , Gorrell MD |
Ref : World J Gastroenterol , 19 :2883 , 2013 |
Abstract : |
PubMedSearch : Chowdhury_2013_World.J.Gastroenterol_19_2883 |
PubMedID: 23704821 |
Title : Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs - Keane_2013_FEBS.Open.Bio_4_43 |
Author(s) : Keane FM , Yao TW , Seelk S , Gall MG , Chowdhury S , Poplawski SE , Lai JH , Li Y , Wu W , Farrell P , Vieira de Ribeiro AJ , Osborne B , Yu DM , Seth D , Rahman K , Haber P , Topaloglu AK , Wang C , Thomson S , Hennessy A , Prins J , Twigg SM , McLennan SV , McCaughan GW , Bachovchin WW , Gorrell MD |
Ref : FEBS Open Bio , 4 :43 , 2013 |
Abstract : |
PubMedSearch : Keane_2013_FEBS.Open.Bio_4_43 |
PubMedID: 24371721 |
Gene_locus related to this paper: human-FAP |
Title : DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues - Harstad_2013_Regul.Pept_186C_26 |
Author(s) : Harstad EB , Rosenblum JS , Gorrell MD , Achanzar WE , Minimo L , Wu J , Rosini-Marthaler L , Gullo R , Ordway ND , Kirby MS , Chadwick KD , Cosma GN , Moyer CF |
Ref : Regul Pept , 186C :26 , 2013 |
Abstract : |
PubMedSearch : Harstad_2013_Regul.Pept_186C_26 |
PubMedID: 23850796 |
Gene_locus related to this paper: rat-dpp9 |
Title : Advances in understanding the expression and function of dipeptidyl peptidase 8 and 9 - Zhang_2013_Mol.Cancer.Res_11_1487 |
Author(s) : Zhang H , Chen Y , Keane FM , Gorrell MD |
Ref : Mol Cancer Research , 11 :1487 , 2013 |
Abstract : |
PubMedSearch : Zhang_2013_Mol.Cancer.Res_11_1487 |
PubMedID: 24038034 |
Title : Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality - Gall_2013_PLoS.One_8_e78378 |
Author(s) : Gall MG , Chen Y , Vieira de Ribeiro AJ , Zhang H , Bailey CG , Spielman DS , Yu DM , Gorrell MD |
Ref : PLoS ONE , 8 :e78378 , 2013 |
Abstract : |
PubMedSearch : Gall_2013_PLoS.One_8_e78378 |
PubMedID: 24223149 |
Gene_locus related to this paper: mouse-dpp9 |
Title : A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling - Yao_2011_Mol.Cancer.Res_9_948 |
Author(s) : Yao TW , Kim WS , Yu DM , Sharbeen G , McCaughan GW , Choi KY , Xia P , Gorrell MD |
Ref : Mol Cancer Research , 9 :948 , 2011 |
Abstract : |
PubMedSearch : Yao_2011_Mol.Cancer.Res_9_948 |
PubMedID: 21622624 |
Gene_locus related to this paper: human-DPP9 |
Title : Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-alpha - Keane_2011_Febs.j_278_1316 |
Author(s) : Keane FM , Nadvi NA , Yao TW , Gorrell MD |
Ref : Febs J , 278 :1316 , 2011 |
Abstract : |
PubMedSearch : Keane_2011_Febs.j_278_1316 |
PubMedID: 21314817 |
Gene_locus related to this paper: human-FAP |
Title : The dipeptidyl peptidase IV family in cancer and cell biology - Yu_2010_FEBS.J_277_1126 |
Author(s) : Yu DM , Yao TW , Chowdhury S , Nadvi NA , Osborne B , Church WB , McCaughan GW , Gorrell MD |
Ref : Febs J , 277 :1126 , 2010 |
Abstract : |
PubMedSearch : Yu_2010_FEBS.J_277_1126 |
PubMedID: 20074209 |
Title : The in vivo expression of dipeptidyl peptidases 8 and 9 - Yu_2009_J.Histochem.Cytochem_57_1025 |
Author(s) : Yu DM , Ajami K , Gall MG , Park J , Lee CS , Evans KA , McLaughlin EA , Pitman MR , Abbott CA , McCaughan GW , Gorrell MD |
Ref : Journal of Histochemistry & Cytochemistry , 57 :1025 , 2009 |
Abstract : |
PubMedSearch : Yu_2009_J.Histochem.Cytochem_57_1025 |
PubMedID: 19581630 |
Gene_locus related to this paper: human-DPP8 , human-DPP9 |
Title : Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8 - Ajami_2008_FEBS.Lett_582_819 |
Author(s) : Ajami K , Pitman MR , Wilson CH , Park J , Menz RI , Starr AE , Cox JH , Abbott CA , Overall CM , Gorrell MD |
Ref : FEBS Letters , 582 :819 , 2008 |
Abstract : |
PubMedSearch : Ajami_2008_FEBS.Lett_582_819 |
PubMedID: 18275857 |
Title : Fibroblast activation protein and chronic liver disease - Wang_2008_Front.Biosci_13_3168 |
Author(s) : Wang XM , Yao TW , Nadvi NA , Osborne B , McCaughan GW , Gorrell MD |
Ref : Front Biosci , 13 :3168 , 2008 |
Abstract : |
PubMedSearch : Wang_2008_Front.Biosci_13_3168 |
PubMedID: 17981786 |
Title : Molecular characterization of a novel dipeptidyl peptidase like 2-short form (DPL2-s) that is highly expressed in the brain and lacks dipeptidyl peptidase activity - Chen_2006_Biochim.Biophys.Acta_1764_33 |
Author(s) : Chen T , Ajami K , McCaughan GW , Gai WP , Gorrell MD , Abbott CA |
Ref : Biochimica & Biophysica Acta , 1764 :33 , 2006 |
Abstract : |
PubMedSearch : Chen_2006_Biochim.Biophys.Acta_1764_33 |
PubMedID: 16290253 |
Title : Dipeptidyl peptidase 8 has post-proline dipeptidyl aminopeptidase and prolyl endopeptidase activities - |
Author(s) : Park J , Ajami K , Yu DM , Gorrell MD |
Ref : Advances in Experimental Medicine & Biology , 575 :93 , 2006 |
PubMedID: 16700512 |
Title : Structure and function in dipeptidyl peptidase IV and related proteins - |
Author(s) : Gorrell MD , Wang XM , Park J , Ajami K , Yu DM , Knott H , Seth D , McCaughan GW |
Ref : Advances in Experimental Medicine & Biology , 575 :45 , 2006 |
PubMedID: 16700507 |
Title : DP8 and DP9 have extra-enzymatic roles in cell adhesion, migration and apoptosis - |
Author(s) : Yu DM , Wang XM , Ajami K , McCaughan GW , Gorrell MD |
Ref : Advances in Experimental Medicine & Biology , 575 :63 , 2006 |
PubMedID: 16700509 |
Gene_locus related to this paper: human-DPP8 , human-DPP9 |
Title : Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis - Yu_2006_FEBS.J_273_2447 |
Author(s) : Yu DM , Wang XM , McCaughan GW , Gorrell MD |
Ref : Febs J , 273 :2447 , 2006 |
Abstract : |
PubMedSearch : Yu_2006_FEBS.J_273_2447 |
PubMedID: 16704418 |
Gene_locus related to this paper: human-DPP8 , human-DPP9 |
Title : Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line - Wang_2005_Hepatology_42_935 |
Author(s) : Wang XM , Yu DM , McCaughan GW , Gorrell MD |
Ref : Hepatology , 42 :935 , 2005 |
Abstract : |
PubMedSearch : Wang_2005_Hepatology_42_935 |
PubMedID: 16175601 |
Gene_locus related to this paper: human-FAP |
Title : Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders - Gorrell_2005_Clin.Sci.(Lond)_108_277 |
Author(s) : Gorrell MD |
Ref : Clinical Science (Lond) , 108 :277 , 2005 |
Abstract : |
PubMedSearch : Gorrell_2005_Clin.Sci.(Lond)_108_277 |
PubMedID: 15584901 |
Title : Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity - Ajami_2004_Biochim.Biophys.Acta_1679_18 |
Author(s) : Ajami K , Abbott CA , McCaughan GW , Gorrell MD |
Ref : Biochimica & Biophysica Acta , 1679 :18 , 2004 |
Abstract : |
PubMedSearch : Ajami_2004_Biochim.Biophys.Acta_1679_18 |
PubMedID: 15245913 |
Title : Dipeptidyl peptidase IV gene family. The DPIV family - Chen_2003_Adv.Exp.Med.Biol_524_79 |
Author(s) : Chen T , Ajami K , McCaughan GW , Gorrell MD , Abbott CA |
Ref : Advances in Experimental Medicine & Biology , 524 :79 , 2003 |
Abstract : |
PubMedSearch : Chen_2003_Adv.Exp.Med.Biol_524_79 |
PubMedID: 12675227 |
Gene_locus related to this paper: human-DPP10 |
Title : Structural requirements for catalysis, expression, and dimerization in the CD26\/DPIV gene family - Ajami_2003_Biochemistry_42_694 |
Author(s) : Ajami K , Abbott CA , Obradovic M , Gysbers V , Kahne T , McCaughan GW , Gorrell MD |
Ref : Biochemistry , 42 :694 , 2003 |
Abstract : |
PubMedSearch : Ajami_2003_Biochemistry_42_694 |
PubMedID: 12534281 |
Gene_locus related to this paper: human-DPP8 , human-DPP9 |
Title : Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8 - Abbott_2000_Eur.J.Biochem_267_6140 |
Author(s) : Abbott CA , Yu DM , Woollatt E , Sutherland GR , McCaughan GW , Gorrell MD |
Ref : European Journal of Biochemistry , 267 :6140 , 2000 |
Abstract : |
PubMedSearch : Abbott_2000_Eur.J.Biochem_267_6140 |
PubMedID: 11012666 |
Gene_locus related to this paper: human-DPP8 |
Title : Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis - Levy_1999_Hepatology_29_1768 |
Author(s) : Levy MT , McCaughan GW , Abbott CA , Park JE , Cunningham AM , Muller E , Rettig WJ , Gorrell MD |
Ref : Hepatology , 29 :1768 , 1999 |
Abstract : |
PubMedSearch : Levy_1999_Hepatology_29_1768 |
PubMedID: 10347120 |
Gene_locus related to this paper: human-FAP |
Title : Two highly conserved glutamic acid residues in the predicted beta propeller domain of dipeptidyl peptidase IV are required for its enzyme activity - Abbott_1999_FEBS.Lett_458_278 |
Author(s) : Abbott CA , McCaughan GW , Gorrell MD |
Ref : FEBS Letters , 458 :278 , 1999 |
Abstract : |
PubMedSearch : Abbott_1999_FEBS.Lett_458_278 |
PubMedID: 10570924 |