human-DPP10

Homo sapiens (Human) DPP-10 Dipeptidyl peptidase IV-related protein-3 KIAA1492 protein (fragment)

Comment

has no active serine No dpp activity || Peptidase S9 DPP_IV

Relationship

Family : DPP4N_Peptidase_S9

Block : X

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

ARWINDTDVV YKSENGHVIK LNIETNATTL LLENTTFVTF KASRHSVSPD LKYVLLAYDV KQIFHYSYTA SYVIYNIHTR EVWELNPPEV EDSVLQYAAW GVQGQQLIYI FENNIYYQPD IKSSSLRLTS SGKEEIIFNG IADWLYEEEL LHSHIAHWWS PDGERLAFLM INDSLVPTMV IPRFTGALYP KGKQYPYPKA GQVNPTIKLY VVNLYGPTHT LELMPPDSFK SREYYITMVK WVSNTKTVVR WLNRPQNISI LTVCETTTGA CSKKYEMTSD TWLSQQNEEP VFSRDGSKFF MTVPVKQGGR GEFHHIAMFL IQSKSEQITV RHLTSGNWEV IKILAYDETT QKIYFLSTES SPRGRQLYSA STEGLLNRQC ISCNFMKEQC TYFDASFSPM NQHFLLFCEG PRVPVVSLHS TDNPAKYFIL ESNSMLKEAI LKKKIGKPEI KILHIDDYEL PLQLSLPKDF MDRNQYALLL IMDEEPGGQL VTDKFHIDWD SVLIDMDNVI VARFDGRGSG FQGLKILQEI HRRLGSVEVK DQITAVKFLL KLPYIDSKRL SIFGKGYGGY IASMILKSDE KLFKCGSVVA PITDLKLYAS AFSERYLGMP SKEESTYQAA SVLHNVHGLK EENILIIHGT ADTKVHFQHS AELIKHLIKA GVNYTMQVYP DEGHNVSEKS KYHLYSTILK FFSDCLKEEI SVLPQEPEED E

References (13)

Title : DPP10 is a new regulator of Nav1.5 channels in human heart - Belau_2019_Int.J.Cardiol_284_68
Author(s) : Belau F , Metzner K , Christ T , Ravens U , Schaefer M , Kunzel S , Li W , Wettwer E , Dobrev D , El-Armouche A , Kammerer S
Ref : Int J Cardiol , 284 :68 , 2019
PubMedID: 30638748
Gene_locus related to this paper: human-DPP10

Title : Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels - Bezerra_2015_Sci.Rep_5_8769
Author(s) : Bezerra GA , Dobrovetsky E , Seitova A , Fedosyuk S , Dhe-Paganon S , Gruber K
Ref : Sci Rep , 5 :8769 , 2015
PubMedID: 25740212
Gene_locus related to this paper: human-DPP10

Title : Crystallization and preliminary X-ray diffraction analysis of human dipeptidyl peptidase 10 (DPPY), a component of voltage-gated potassium channels - Bezerra_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_68_214
Author(s) : Bezerra GA , Dobrovetsky E , Seitova A , Dhe-Paganon S , Gruber K
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 68 :214 , 2012
PubMedID: 22298003
Gene_locus related to this paper: human-DPP10

Title : Analyses of associations between three positionally cloned asthma candidate genes and asthma or asthma-related phenotypes in a Chinese population - Zhou_2009_BMC.Med.Genet_10_123
Author(s) : Zhou H , Hong X , Jiang S , Dong H , Xu X
Ref : BMC Med Genet , 10 :123 , 2009
PubMedID: 19951440
Gene_locus related to this paper: human-DPP10

Title : Species and tissue differences in the expression of DPPY splicing variants - Takimoto_2006_Biochem.Biophys.Res.Commun_348_1094
Author(s) : Takimoto K , Hayashi Y , Ren X , Yoshimura N
Ref : Biochemical & Biophysical Research Communications , 348 :1094 , 2006
PubMedID: 16899223
Gene_locus related to this paper: human-DPP10 , ratno-q6q629

Title : Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10) - Jerng_2004_Biophys.J_87_2380
Author(s) : Jerng HH , Qian Y , Pfaffinger PJ
Ref : Biophysical Journal , 87 :2380 , 2004
PubMedID: 15454437
Gene_locus related to this paper: human-DPP6 , human-DPP10

Title : Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases - Qi_2003_Biochem.J_373_179
Author(s) : Qi SY , Riviere PJ , Trojnar J , Junien JL , Akinsanya KO
Ref : Biochemical Journal , 373 :179 , 2003
PubMedID: 12662155
Gene_locus related to this paper: human-DPP8 , human-DPP9 , human-DPP10 , mouse-dpp9 , mouse-dpp10

Title : Dipeptidyl peptidase IV gene family. The DPIV family - Chen_2003_Adv.Exp.Med.Biol_524_79
Author(s) : Chen T , Ajami K , McCaughan GW , Gorrell MD , Abbott CA
Ref : Advances in Experimental Medicine & Biology , 524 :79 , 2003
PubMedID: 12675227
Gene_locus related to this paper: human-DPP10

Title : Positional cloning of a novel gene influencing asthma from chromosome 2q14. - Allen_2003_Nat.Genet_35_258
Author(s) : Allen M , Heinzmann A , Noguchi E , Abecasis G , Broxholme J , Ponting CP , Bhattacharyya S , Tinsley J , Zhang Y , Holt R , Jones EY , Lench N , Carey A , Jones H , Dickens NJ , Dimon C , Nicholls R , Baker C , Xue L , Townsend E , Kabesch M , Weiland SK , Carr D , von Mutius E , Adcock IM , Barnes PJ , Lathrop GM , Edwards M , Moffatt MF , Cookson WO
Ref : Nat Genet , 35 :258\ , 2003
PubMedID: 14566338
Gene_locus related to this paper: human-DPP10

Title : The CD26-related dipeptidyl aminopeptidase-like protein DPPX is a critical component of neuronal A-type K+ channels - Nadal_2003_Neuron_37_449
Author(s) : Nadal MS , Ozaita A , Amarillo Y , Vega-Saenz de Miera E , Ma Y , Mo W , Goldberg EM , Misumi Y , Ikehara Y , Neubert TA , Rudy B
Ref : Neuron , 37 :449 , 2003
PubMedID: 12575952
Gene_locus related to this paper: human-DPP6 , human-DPP10

Title : Biosynthesis and characterization of the brain-specific membrane protein DPPX, a dipeptidyl peptidase IV-related protein - Kin_2001_J.Biochem_129_289
Author(s) : Kin Y , Misumi Y , Ikehara Y
Ref : J Biochem , 129 :289 , 2001
PubMedID: 11173531
Gene_locus related to this paper: human-DPP6 , human-DPP10

Title : Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro - Nagase_2000_DNA.Res_7_143
Author(s) : Nagase T , Kikuno R , Ishikawa K , Hirosawa M , Ohara O
Ref : DNA Research , 7 :143 , 2000
PubMedID: 10819331
Gene_locus related to this paper: human-DPP10

Title : Differential expression of two distinct forms of mRNA encoding members of a dipeptidyl aminopeptidase family - Wada_1992_Proc.Natl.Acad.Sci.U.S.A_89_197
Author(s) : Wada K , Yokotani N , Hunter C , Doi K , Wenthold RJ , Shimasaki S
Ref : Proc Natl Acad Sci U S A , 89 :197 , 1992
PubMedID: 1729689
Gene_locus related to this paper: bovin-dpp6 , human-DPP6 , human-DPP10 , ratno-dpp6