Full name : Horenstein Nicole A
First name : Nicole A
Mail : Department of Chemistry, University of Florida College of Medicine, Gainesville, Florida 32610
Zip Code :
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Country : USA
Email : horen@chem.ufl.edu
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Comment
| Title : Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant beta Subunits Acquire Sensitivity to alpha7-Selective Positive Allosteric Modulators - Stokes_2019_J.Pharmacol.Exp.Ther_370_252 |
| Author(s) : Stokes C , Garai S , Kulkarni AR , Cantwell LN , Noviello CM , Hibbs RE , Horenstein NA , Abboud KA , Thakur GA , Papke RL |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 370 :252 , 2019 |
| Abstract : |
| PubMedSearch : Stokes_2019_J.Pharmacol.Exp.Ther_370_252 |
| PubMedID: 31175218 |
| Title : The Activity of GAT107, an Allosteric Activator and Positive Modulator of alpha7 Nicotinic Acetylcholine Receptors (nAChR), Is Regulated by Aromatic Amino Acids That Span the Subunit Interface - Papke_2014_J.Biol.Chem_289_4515 |
| Author(s) : Papke RL , Horenstein NA , Kulkarni AR , Stokes C , Corrie LW , Maeng CY , Thakur GA |
| Ref : Journal of Biological Chemistry , 289 :4515 , 2014 |
| Abstract : |
| PubMedSearch : Papke_2014_J.Biol.Chem_289_4515 |
| PubMedID: 24362025 |
| Title : Synthesis and evaluation of a conditionally-silent agonist for the alpha7 nicotinic acetylcholine receptor - Chojnacka_2013_Bioorg.Med.Chem.Lett_23_4145 |
| Author(s) : Chojnacka K , Papke RL , Horenstein NA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :4145 , 2013 |
| Abstract : |
| PubMedSearch : Chojnacka_2013_Bioorg.Med.Chem.Lett_23_4145 |
| PubMedID: 23746476 |
| Title : Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines - Isaacson_2013_Biochem.Pharmacol_85_817 |
| Author(s) : Isaacson MD , Horenstein NA , Stokes C , Kem WR , Papke RL |
| Ref : Biochemical Pharmacology , 85 :817 , 2013 |
| Abstract : |
| PubMedSearch : Isaacson_2013_Biochem.Pharmacol_85_817 |
| PubMedID: 23352650 |
| Title : Potential state-selective hydrogen bond formation can modulate activation and desensitization of the alpha7 nicotinic acetylcholine receptor - Wang_2012_J.Biol.Chem_287_21957 |
| Author(s) : Wang J , Papke RL , Stokes C , Horenstein NA |
| Ref : Journal of Biological Chemistry , 287 :21957 , 2012 |
| Abstract : |
| PubMedSearch : Wang_2012_J.Biol.Chem_287_21957 |
| PubMedID: 22556416 |
| Title : Poster: Positive and negative cooperativity of agonist and allosteric modulator binding in alpha7 nAChR: Looking for the therapeutic window - |
| Author(s) : Papke RL , Williams DK , Wang J , Horenstein NA |
| Ref : Biochemical Pharmacology , 82 :1031 , 2011 |
| PubMedID: |
| Title : Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper - Papke_2011_Neuropharmacol_60_159 |
| Author(s) : Papke RL , Stokes C , Williams DK , Wang J , Horenstein NA |
| Ref : Neuropharmacology , 60 :159 , 2011 |
| Abstract : |
| PubMedSearch : Papke_2011_Neuropharmacol_60_159 |
| PubMedID: 20650284 |
| Title : The effective opening of nicotinic acetylcholine receptors with single agonist binding sites - Williams_2011_J.Gen.Physiol_137_369 |
| Author(s) : Williams DK , Stokes C , Horenstein NA , Papke RL |
| Ref : Journal of General Physiology , 137 :369 , 2011 |
| Abstract : |
| PubMedSearch : Williams_2011_J.Gen.Physiol_137_369 |
| PubMedID: 21444659 |
| Title : Tethered agonist analogs as site-specific probes for domains of the human alpha7 nicotinic acetylcholine receptor that differentially regulate activation and desensitization - Wang_2010_Mol.Pharmacol_78_1012 |
| Author(s) : Wang J , Horenstein NA , Stokes C , Papke RL |
| Ref : Molecular Pharmacology , 78 :1012 , 2010 |
| Abstract : |
| PubMedSearch : Wang_2010_Mol.Pharmacol_78_1012 |
| PubMedID: 20823218 |
| Title : Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine - Papke_2009_J.Pharmacol.Exp.Ther_329_791 |
| Author(s) : Papke RL , Kem WR , Soti F , Lopez-Hernandez GY , Horenstein NA |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 329 :791 , 2009 |
| Abstract : |
| PubMedSearch : Papke_2009_J.Pharmacol.Exp.Ther_329_791 |
| PubMedID: 19223664 |
| Title : Multiple pharmacophores for the selective activation of nicotinic alpha7-type acetylcholine receptors - Horenstein_2008_Mol.Pharmacol_74_1496 |
| Author(s) : Horenstein NA , Leonik FM , Papke RL |
| Ref : Molecular Pharmacology , 74 :1496 , 2008 |
| Abstract : |
| PubMedSearch : Horenstein_2008_Mol.Pharmacol_74_1496 |
| PubMedID: 18768388 |
| Title : The effects of subunit composition on the inhibition of nicotinic receptors by the amphipathic blocker 2,2,6,6-tetramethylpiperidin-4-yl heptanoate - Papke_2005_Mol.Pharmacol_67_1977 |
| Author(s) : Papke RL , Buhr JD , Francis MM , Choi KI , Thinschmidt JS , Horenstein NA |
| Ref : Molecular Pharmacology , 67 :1977 , 2005 |
| Abstract : |
| PubMedSearch : Papke_2005_Mol.Pharmacol_67_1977 |
| PubMedID: 15761116 |
| Title : The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion - Papke_2005_Bioorg.Med.Chem.Lett_15_3874 |
| Author(s) : Papke RL , Zheng G , Horenstein NA , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :3874 , 2005 |
| Abstract : |
| PubMedSearch : Papke_2005_Bioorg.Med.Chem.Lett_15_3874 |
| PubMedID: 16005216 |
| Title : The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors - Stokes_2004_Mol.Pharmacol_66_14 |
| Author(s) : Stokes C , Papke JK , Horenstein NA , Kem WR , McCormack TJ , Papke RL |
| Ref : Molecular Pharmacology , 66 :14 , 2004 |
| Abstract : |
| PubMedSearch : Stokes_2004_Mol.Pharmacol_66_14 |
| PubMedID: 15213292 |