Full name : Kem William R
First name : William R
Mail : Department of Pharmacology and Therapeutics, University of Florida College of Medicine, P.O. Box 100267 Gainesville, Florida, 32610
Zip Code :
City :
Country : USA
Email : ude.lfu@mekrw
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Comment
| Title : Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines - Isaacson_2013_Biochem.Pharmacol_85_817 |
| Author(s) : Isaacson MD , Horenstein NA , Stokes C , Kem WR , Papke RL |
| Ref : Biochemical Pharmacology , 85 :817 , 2013 |
| Abstract : |
| PubMedSearch : Isaacson_2013_Biochem.Pharmacol_85_817 |
| PubMedID: 23352650 |
| Title : APS8, a Polymeric Alkylpyridinium Salt Blocks alpha7 nAChR and Induces Apoptosis in Non-Small Cell Lung Carcinoma - Zovko_2013_Mar.Drugs_11_2574 |
| Author(s) : Zovko A , Viktorsson K , Lewensohn R , Kolosa K , Filipic M , Xing H , Kem WR , Paleari L , Turk T |
| Ref : Mar Drugs , 11 :2574 , 2013 |
| Abstract : |
| PubMedSearch : Zovko_2013_Mar.Drugs_11_2574 |
| PubMedID: 23880932 |
| Title : Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia - Tregellas_2011_Biol.Psychiatry_69_7 |
| Author(s) : Tregellas JR , Tanabe J , Rojas DC , Shatti S , Olincy A , Johnson L , Martin LF , Soti F , Kem WR , Leonard S , Freedman R |
| Ref : Biological Psychiatry , 69 :7 , 2011 |
| Abstract : |
| PubMedSearch : Tregellas_2011_Biol.Psychiatry_69_7 |
| PubMedID: 20728875 |
| Title : Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia - Tregellas_2010_Neuropsychopharmacology_35_938 |
| Author(s) : Tregellas JR , Olincy A , Johnson L , Tanabe J , Shatti S , Martin LF , Singel D , Du YP , Soti F , Kem WR , Freedman R |
| Ref : Neuropsychopharmacology , 35 :938 , 2010 |
| Abstract : |
| PubMedSearch : Tregellas_2010_Neuropsychopharmacology_35_938 |
| PubMedID: 19956085 |
| Title : Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of alpha7 nicotinic receptors and internalization of NMDA receptors - Shen_2010_Br.J.Pharmacol_161_127 |
| Author(s) : Shen H , Kihara T , Hongo H , Wu X , Kem WR , Shimohama S , Akaike A , Niidome T , Sugimoto H |
| Ref : British Journal of Pharmacology , 161 :127 , 2010 |
| Abstract : |
| PubMedSearch : Shen_2010_Br.J.Pharmacol_161_127 |
| PubMedID: 20718745 |
| Title : Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine - Papke_2009_J.Pharmacol.Exp.Ther_329_791 |
| Author(s) : Papke RL , Kem WR , Soti F , Lopez-Hernandez GY , Horenstein NA |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 329 :791 , 2009 |
| Abstract : |
| PubMedSearch : Papke_2009_J.Pharmacol.Exp.Ther_329_791 |
| PubMedID: 19223664 |
| Title : Poster: Isoanatabine, a naturally occurring alpha4\/beta2 nicotinic receptor agonist - |
| Author(s) : Xing H , Rouchaud A , Keshwah S , Kem WR |
| Ref : Biochemical Pharmacology , 78 :906 , 2009 |
| PubMedID: |
| Title : Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795 - Lopez-Hernandez_2009_Neuropharmacol_56_821 |
| Author(s) : Lopez-Hernandez GY , Thinschmidt JS , Morain P , Trocme-Thibierge C , Kem WR , Soti F , Papke RL |
| Ref : Neuropharmacology , 56 :821 , 2009 |
| Abstract : |
| PubMedSearch : Lopez-Hernandez_2009_Neuropharmacol_56_821 |
| PubMedID: 19705574 |
| Title : Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor - Hibbs_2009_EMBO.J_28_3040 |
| Author(s) : Hibbs RE , Sulzenbacher G , Shi J , Talley TT , Conrod S , Kem WR , Taylor P , Marchot P , Bourne Y |
| Ref : EMBO Journal , 28 :3040 , 2009 |
| Abstract : |
| PubMedSearch : Hibbs_2009_EMBO.J_28_3040 |
| PubMedID: 19696737 |
| Title : Initial phase 2 trial of a nicotinic agonist in schizophrenia - Freedman_2008_Am.J.Psychiatry_165_1040 |
| Author(s) : Freedman R , Olincy A , Buchanan RW , Harris JG , Gold JM , Johnson L , Allensworth D , Guzman-Bonilla A , Clement B , Ball MP , Kutnick J , Pender V , Martin LF , Stevens KE , Wagner BD , Zerbe GO , Soti F , Kem WR |
| Ref : Am J Psychiatry , 165 :1040 , 2008 |
| Abstract : |
| PubMedSearch : Freedman_2008_Am.J.Psychiatry_165_1040 |
| PubMedID: 18381905 |
| Title : Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia - Olincy_2006_Arch.Gen.Psychiatry_63_630 |
| Author(s) : Olincy A , Harris JG , Johnson LL , Pender V , Kongs S , Allensworth D , Ellis J , Zerbe GO , Leonard S , Stevens KE , Stevens JO , Martin L , Adler LE , Soti F , Kem WR , Freedman R |
| Ref : Arch Gen Psychiatry , 63 :630 , 2006 |
| Abstract : |
| PubMedSearch : Olincy_2006_Arch.Gen.Psychiatry_63_630 |
| PubMedID: 16754836 |
| Title : The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors - Stokes_2004_Mol.Pharmacol_66_14 |
| Author(s) : Stokes C , Papke JK , Horenstein NA , Kem WR , McCormack TJ , Papke RL |
| Ref : Molecular Pharmacology , 66 :14 , 2004 |
| Abstract : |
| PubMedSearch : Stokes_2004_Mol.Pharmacol_66_14 |
| PubMedID: 15213292 |
| Title : Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex - Summers_1997_Jpn.J.Pharmacol_74_139 |
| Author(s) : Summers KL , Kem WR , Giacobini E |
| Ref : Japanese Journal of Pharmacology , 74 :139 , 1997 |
| Abstract : |
| PubMedSearch : Summers_1997_Jpn.J.Pharmacol_74_139 |
| PubMedID: 9243321 |