Full name : Dias Jose
First name : Jose
Mail : French Armed Forces Biomedical Research Institute, Toxicology and chemical risks department, Bretigny-sur-Orge
Zip Code :
City :
Country : France
Email : jose.dias@irba.fr
Phone :
Fax :
Website :
Directory :
Comment
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__ |
| Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__ |
| PubMedID: 40779804 |
| Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__ |
| Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__ |
| PubMedID: 40779804 |
| Title : Specific Rosetta-based protein-peptide prediction protocol allows the design of novel cholinesterase inhibitor peptides - Sanchis_2025_Bioorg.Chem_156_108202 |
| Author(s) : Sanchis I , Aimaretti F , Lupotti M , Rietmann A , Dias J , Brazzolotto X , Spinelli R , Siano A S |
| Ref : Bioorg Chem , 156 :108202 , 2025 |
| Abstract : |
| PubMedSearch : Sanchis_2025_Bioorg.Chem_156_108202 |
| PubMedID: 39862740 |
| Title : Expanding the reactive chemistry toolbox - warhead screening for covalent butyrylcholinesterase inhibitors - Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| Author(s) : Meden A , Brazzolotto X , Dias J , Stojan J , Knez D , Gobec S |
| Ref : Chemico-Biological Interactions , :111841 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| PubMedID: 41276059 |
| Title : Lead Optimization of a Butyrylcholinesterase Inhibitor for the Treatment of Alzheimer's Disease - Kosak_2025_J.Med.Chem__ |
| Author(s) : Kosak U , Strasek Benedik N , Knez D , Zakelj S , Trontelj J , Pislar A , Horvat S , Bolje A , Znidarsic N , Grgurevic N , Svara T , Kljun J , Skrzypczak-Wiercioch A , Lv B , Xiong Y , Wang Q , Bian R , Shao J , Dias J , Nachon F , Brazzolotto X , Stojan J , Sun H , Salat K , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_J.Med.Chem__ |
| PubMedID: 40454648 |
| Gene_locus related to this paper: human-BCHE |
| Title : Lead Optimization of a Butyrylcholinesterase Inhibitor for the Treatment of Alzheimer's Disease - Kosak_2025_J.Med.Chem__ |
| Author(s) : Kosak U , Strasek Benedik N , Knez D , Zakelj S , Trontelj J , Pislar A , Horvat S , Bolje A , Znidarsic N , Grgurevic N , Svara T , Kljun J , Skrzypczak-Wiercioch A , Lv B , Xiong Y , Wang Q , Bian R , Shao J , Dias J , Nachon F , Brazzolotto X , Stojan J , Sun H , Salat K , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_J.Med.Chem__ |
| PubMedID: 40454648 |
| Gene_locus related to this paper: human-BCHE |
| Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111681 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| PubMedID: 40750068 |
| Gene_locus related to this paper: human-BCHE |
| Title : Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670 |
| Author(s) : Kosak U , Knez D , Benetik SF , Sokolov PM , Pislar A , Horvat S , Stojan J , Lv B , Zhang W , Wang Y , Wang Q , Igert A , Dias J , Nachon F , Brazzolotto X , Sun H , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111670 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670 |
| PubMedID: 40712769 |
| Gene_locus related to this paper: human-BCHE |
| Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111681 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| PubMedID: 40750068 |
| Gene_locus related to this paper: human-BCHE |
| Title : Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670 |
| Author(s) : Kosak U , Knez D , Benetik SF , Sokolov PM , Pislar A , Horvat S , Stojan J , Lv B , Zhang W , Wang Y , Wang Q , Igert A , Dias J , Nachon F , Brazzolotto X , Sun H , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111670 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670 |
| PubMedID: 40712769 |
| Gene_locus related to this paper: human-BCHE |
| Title : Lead Optimization of a Butyrylcholinesterase Inhibitor for the Treatment of Alzheimer's Disease - Kosak_2025_J.Med.Chem__ |
| Author(s) : Kosak U , Strasek Benedik N , Knez D , Zakelj S , Trontelj J , Pislar A , Horvat S , Bolje A , Znidarsic N , Grgurevic N , Svara T , Kljun J , Skrzypczak-Wiercioch A , Lv B , Xiong Y , Wang Q , Bian R , Shao J , Dias J , Nachon F , Brazzolotto X , Stojan J , Sun H , Salat K , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_J.Med.Chem__ |
| PubMedID: 40454648 |
| Gene_locus related to this paper: human-BCHE |
| Title : Expanding the reactive chemistry toolbox - warhead screening for covalent butyrylcholinesterase inhibitors - Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| Author(s) : Meden A , Brazzolotto X , Dias J , Stojan J , Knez D , Gobec S |
| Ref : Chemico-Biological Interactions , :111841 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| PubMedID: 41276059 |
| Title : Specific Rosetta-based protein-peptide prediction protocol allows the design of novel cholinesterase inhibitor peptides - Sanchis_2025_Bioorg.Chem_156_108202 |
| Author(s) : Sanchis I , Aimaretti F , Lupotti M , Rietmann A , Dias J , Brazzolotto X , Spinelli R , Siano A S |
| Ref : Bioorg Chem , 156 :108202 , 2025 |
| Abstract : |
| PubMedSearch : Sanchis_2025_Bioorg.Chem_156_108202 |
| PubMedID: 39862740 |
| Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111681 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681 |
| PubMedID: 40750068 |
| Gene_locus related to this paper: human-BCHE |
| Title : Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670 |
| Author(s) : Kosak U , Knez D , Benetik SF , Sokolov PM , Pislar A , Horvat S , Stojan J , Lv B , Zhang W , Wang Y , Wang Q , Igert A , Dias J , Nachon F , Brazzolotto X , Sun H , Gobec S |
| Ref : Chemico-Biological Interactions , 420 :111670 , 2025 |
| Abstract : |
| PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670 |
| PubMedID: 40712769 |
| Gene_locus related to this paper: human-BCHE |
| Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__ |
| Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__ |
| PubMedID: 40779804 |
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Expanding the reactive chemistry toolbox - warhead screening for covalent butyrylcholinesterase inhibitors - Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| Author(s) : Meden A , Brazzolotto X , Dias J , Stojan J , Knez D , Gobec S |
| Ref : Chemico-Biological Interactions , :111841 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| PubMedID: 41276059 |
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Specific Rosetta-based protein-peptide prediction protocol allows the design of novel cholinesterase inhibitor peptides - Sanchis_2025_Bioorg.Chem_156_108202 |
| Author(s) : Sanchis I , Aimaretti F , Lupotti M , Rietmann A , Dias J , Brazzolotto X , Spinelli R , Siano A S |
| Ref : Bioorg Chem , 156 :108202 , 2025 |
| Abstract : |
| PubMedSearch : Sanchis_2025_Bioorg.Chem_156_108202 |
| PubMedID: 39862740 |
| Title : The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives - Voros_2024_Chem.Biol.Interact__110973 |
| Author(s) : Voros C , Dias J , Timperley CM , Nachon F , Brown RCD , Baati R |
| Ref : Chemico-Biological Interactions , :110973 , 2024 |
| Abstract : |
| PubMedSearch : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedID: 38574837 |
| Title : The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives - Voros_2024_Chem.Biol.Interact__110973 |
| Author(s) : Voros C , Dias J , Timperley CM , Nachon F , Brown RCD , Baati R |
| Ref : Chemico-Biological Interactions , :110973 , 2024 |
| Abstract : |
| PubMedSearch : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedID: 38574837 |
| Title : Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases - Kolic_2024_Biomolecules_14_588 |
| Author(s) : Kolic D , Sinko G , Jean L , Chioua M , Dias J , Marco-Contelles J , Kovarik, Z , Kovarik Z |
| Ref : Biomolecules , 14 :588 , 2024 |
| Abstract : |
| PubMedSearch : Kolic_2024_Biomolecules_14_588 |
| PubMedID: 38785995 |
| Title : Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases - Kolic_2024_Biomolecules_14_588 |
| Author(s) : Kolic D , Sinko G , Jean L , Chioua M , Dias J , Marco-Contelles J , Kovarik, Z , Kovarik Z |
| Ref : Biomolecules , 14 :588 , 2024 |
| Abstract : |
| PubMedSearch : Kolic_2024_Biomolecules_14_588 |
| PubMedID: 38785995 |
| Title : The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives - Voros_2024_Chem.Biol.Interact__110973 |
| Author(s) : Voros C , Dias J , Timperley CM , Nachon F , Brown RCD , Baati R |
| Ref : Chemico-Biological Interactions , :110973 , 2024 |
| Abstract : |
| PubMedSearch : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedID: 38574837 |
| Title : Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases - Kolic_2024_Biomolecules_14_588 |
| Author(s) : Kolic D , Sinko G , Jean L , Chioua M , Dias J , Marco-Contelles J , Kovarik, Z , Kovarik Z |
| Ref : Biomolecules , 14 :588 , 2024 |
| Abstract : |
| PubMedSearch : Kolic_2024_Biomolecules_14_588 |
| PubMedID: 38785995 |
| Title : Protective mechanisms of a microbial oil against hypercholesterolemia: evidence from a zebrafish model - Gora_2023_Front.Nutr_10_1161119 |
| Author(s) : Gora AH , Rehman S , Dias J , Fernandes JMO , Olsvik PA , Sorensen M , Kiron V |
| Ref : Front Nutr , 10 :1161119 , 2023 |
| Abstract : |
| PubMedSearch : Gora_2023_Front.Nutr_10_1161119 |
| PubMedID: 37435570 |
| Gene_locus related to this paper: danre-a0a8m1p7r5 |
| Title : Inhibition of Human Cholinesterases and In Vitro beta-Amyloid Aggregation by Rationally Designed Peptides - Sanchis_2023_ChemMedChem__e202200691 |
| Author(s) : Sanchis I , Spinelli R , Dias J , Brazzolotto X , Rietmann A , Aimaretti F , Siano AS |
| Ref : ChemMedChem , :e202200691 , 2023 |
| Abstract : |
| PubMedSearch : Sanchis_2023_ChemMedChem__e202200691 |
| PubMedID: 36995341 |
| Title : Protective mechanisms of a microbial oil against hypercholesterolemia: evidence from a zebrafish model - Gora_2023_Front.Nutr_10_1161119 |
| Author(s) : Gora AH , Rehman S , Dias J , Fernandes JMO , Olsvik PA , Sorensen M , Kiron V |
| Ref : Front Nutr , 10 :1161119 , 2023 |
| Abstract : |
| PubMedSearch : Gora_2023_Front.Nutr_10_1161119 |
| PubMedID: 37435570 |
| Gene_locus related to this paper: danre-a0a8m1p7r5 |
| Title : Inhibition of Human Cholinesterases and In Vitro beta-Amyloid Aggregation by Rationally Designed Peptides - Sanchis_2023_ChemMedChem__e202200691 |
| Author(s) : Sanchis I , Spinelli R , Dias J , Brazzolotto X , Rietmann A , Aimaretti F , Siano AS |
| Ref : ChemMedChem , :e202200691 , 2023 |
| Abstract : |
| PubMedSearch : Sanchis_2023_ChemMedChem__e202200691 |
| PubMedID: 36995341 |
| Title : Inhibition of Human Cholinesterases and In Vitro beta-Amyloid Aggregation by Rationally Designed Peptides - Sanchis_2023_ChemMedChem__e202200691 |
| Author(s) : Sanchis I , Spinelli R , Dias J , Brazzolotto X , Rietmann A , Aimaretti F , Siano AS |
| Ref : ChemMedChem , :e202200691 , 2023 |
| Abstract : |
| PubMedSearch : Sanchis_2023_ChemMedChem__e202200691 |
| PubMedID: 36995341 |
| Title : Protective mechanisms of a microbial oil against hypercholesterolemia: evidence from a zebrafish model - Gora_2023_Front.Nutr_10_1161119 |
| Author(s) : Gora AH , Rehman S , Dias J , Fernandes JMO , Olsvik PA , Sorensen M , Kiron V |
| Ref : Front Nutr , 10 :1161119 , 2023 |
| Abstract : |
| PubMedSearch : Gora_2023_Front.Nutr_10_1161119 |
| PubMedID: 37435570 |
| Gene_locus related to this paper: danre-a0a8m1p7r5 |
| Title : A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning - Da Silva_2022_J.Med.Chem_65_4649 |
| Author(s) : Da Silva O , Probst N , Landry C , Hanak AS , Warnault P , Coisne C , Calas AG , Gosselet F , Courageux C , Gastellier AJ , Trancart M , Baati R , Dehouck MP , Jean L , Nachon F , Renard PY , Dias J |
| Ref : Journal of Medicinal Chemistry , 65 :4649 , 2022 |
| Abstract : |
| PubMedSearch : Da Silva_2022_J.Med.Chem_65_4649 |
| PubMedID: 35255209 |
| Gene_locus related to this paper: human-ACHE |
| Title : Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions - Nachon_2022_Chembiochem_23_e202200456 |
| Author(s) : Nachon F , Brazzolotto X , Dias J , Courageux C , Drozdz W , Cao XY , Stefankiewicz AR , Lehn JM |
| Ref : Chembiochem , 23 :e202200456 , 2022 |
| Abstract : |
| PubMedSearch : Nachon_2022_Chembiochem_23_e202200456 |
| PubMedID: 36193860 |
| Gene_locus related to this paper: human-BCHE |
| Title : A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning - Da Silva_2022_J.Med.Chem_65_4649 |
| Author(s) : Da Silva O , Probst N , Landry C , Hanak AS , Warnault P , Coisne C , Calas AG , Gosselet F , Courageux C , Gastellier AJ , Trancart M , Baati R , Dehouck MP , Jean L , Nachon F , Renard PY , Dias J |
| Ref : Journal of Medicinal Chemistry , 65 :4649 , 2022 |
| Abstract : |
| PubMedSearch : Da Silva_2022_J.Med.Chem_65_4649 |
| PubMedID: 35255209 |
| Gene_locus related to this paper: human-ACHE |
| Title : A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning - Da Silva_2022_J.Med.Chem_65_4649 |
| Author(s) : Da Silva O , Probst N , Landry C , Hanak AS , Warnault P , Coisne C , Calas AG , Gosselet F , Courageux C , Gastellier AJ , Trancart M , Baati R , Dehouck MP , Jean L , Nachon F , Renard PY , Dias J |
| Ref : Journal of Medicinal Chemistry , 65 :4649 , 2022 |
| Abstract : |
| PubMedSearch : Da Silva_2022_J.Med.Chem_65_4649 |
| PubMedID: 35255209 |
| Gene_locus related to this paper: human-ACHE |
| Title : From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series - Meden_2022_Eur.J.Med.Chem_230_114248 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Nachon F , Dias J , Svete J , Stojan J , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 230 :114248 , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Eur.J.Med.Chem_230_114248 |
| PubMedID: 35299116 |
| Title : From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series - Meden_2022_Eur.J.Med.Chem_230_114248 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Nachon F , Dias J , Svete J , Stojan J , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 230 :114248 , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Eur.J.Med.Chem_230_114248 |
| PubMedID: 35299116 |
| Title : Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions - Nachon_2022_Chembiochem_23_e202200456 |
| Author(s) : Nachon F , Brazzolotto X , Dias J , Courageux C , Drozdz W , Cao XY , Stefankiewicz AR , Lehn JM |
| Ref : Chembiochem , 23 :e202200456 , 2022 |
| Abstract : |
| PubMedSearch : Nachon_2022_Chembiochem_23_e202200456 |
| PubMedID: 36193860 |
| Gene_locus related to this paper: human-BCHE |
| Title : From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series - Meden_2022_Eur.J.Med.Chem_230_114248 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Nachon F , Dias J , Svete J , Stojan J , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 230 :114248 , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Eur.J.Med.Chem_230_114248 |
| PubMedID: 35299116 |
| Title : Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions - Nachon_2022_Chembiochem_23_e202200456 |
| Author(s) : Nachon F , Brazzolotto X , Dias J , Courageux C , Drozdz W , Cao XY , Stefankiewicz AR , Lehn JM |
| Ref : Chembiochem , 23 :e202200456 , 2022 |
| Abstract : |
| PubMedSearch : Nachon_2022_Chembiochem_23_e202200456 |
| PubMedID: 36193860 |
| Gene_locus related to this paper: human-BCHE |
| Title : Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases - Chavarria_2021_Antioxidants.(Basel)_10_329 |
| Author(s) : Chavarria D , Da Silva O , Benfeito S , Barreiro S , Garrido J , Cagide F , Soares P , Remiao F , Brazzolotto X , Nachon F , Oliveira PJ , Dias J , Borges F |
| Ref : Antioxidants (Basel) , 10 :329 , 2021 |
| Abstract : |
| PubMedSearch : Chavarria_2021_Antioxidants.(Basel)_10_329 |
| PubMedID: 33672269 |
| Gene_locus related to this paper: human-ACHE , human-BCHE |
| Title : Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases - Chavarria_2021_Antioxidants.(Basel)_10_329 |
| Author(s) : Chavarria D , Da Silva O , Benfeito S , Barreiro S , Garrido J , Cagide F , Soares P , Remiao F , Brazzolotto X , Nachon F , Oliveira PJ , Dias J , Borges F |
| Ref : Antioxidants (Basel) , 10 :329 , 2021 |
| Abstract : |
| PubMedSearch : Chavarria_2021_Antioxidants.(Basel)_10_329 |
| PubMedID: 33672269 |
| Gene_locus related to this paper: human-ACHE , human-BCHE |
| Title : Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database - Miles_2021_Chem.Biol.Drug.Des__ |
| Author(s) : Miles JA , Ng JH , Sreenivas BY , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP |
| Ref : Chemical Biology Drug Des , : , 2021 |
| Abstract : |
| PubMedSearch : Miles_2021_Chem.Biol.Drug.Des__ |
| PubMedID: 33455074 |
| Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021 |
| Abstract : |
| PubMedSearch : Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| PubMedID: 33838585 |
| Title : Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases - Chavarria_2021_Antioxidants.(Basel)_10_329 |
| Author(s) : Chavarria D , Da Silva O , Benfeito S , Barreiro S , Garrido J , Cagide F , Soares P , Remiao F , Brazzolotto X , Nachon F , Oliveira PJ , Dias J , Borges F |
| Ref : Antioxidants (Basel) , 10 :329 , 2021 |
| Abstract : |
| PubMedSearch : Chavarria_2021_Antioxidants.(Basel)_10_329 |
| PubMedID: 33672269 |
| Gene_locus related to this paper: human-ACHE , human-BCHE |
| Title : Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database - Miles_2021_Chem.Biol.Drug.Des__ |
| Author(s) : Miles JA , Ng JH , Sreenivas BY , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP |
| Ref : Chemical Biology Drug Des , : , 2021 |
| Abstract : |
| PubMedSearch : Miles_2021_Chem.Biol.Drug.Des__ |
| PubMedID: 33455074 |
| Title : Development of versatile and potent monoquaternary reactivators of acetylcholinesterase - Gorecki_2021_Arch.Toxicol__ |
| Author(s) : Gorecki L , Hepnarova V , Karasova JZ , Hrabinova M , Courageux C , Dias J , Kucera T , Kobrlova T , Muckova L , Prchal L , Malinak D , Jun D , Musilek K , Worek F , Nachon F , Soukup O , Korabecny J |
| Ref : Archives of Toxicology , : , 2021 |
| Abstract : |
| PubMedSearch : Gorecki_2021_Arch.Toxicol__ |
| PubMedID: 33517499 |
| Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021 |
| Abstract : |
| PubMedSearch : Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| PubMedID: 33838585 |
| Title : Development of versatile and potent monoquaternary reactivators of acetylcholinesterase - Gorecki_2021_Arch.Toxicol__ |
| Author(s) : Gorecki L , Hepnarova V , Karasova JZ , Hrabinova M , Courageux C , Dias J , Kucera T , Kobrlova T , Muckova L , Prchal L , Malinak D , Jun D , Musilek K , Worek F , Nachon F , Soukup O , Korabecny J |
| Ref : Archives of Toxicology , : , 2021 |
| Abstract : |
| PubMedSearch : Gorecki_2021_Arch.Toxicol__ |
| PubMedID: 33517499 |
| Title : Development of versatile and potent monoquaternary reactivators of acetylcholinesterase - Gorecki_2021_Arch.Toxicol__ |
| Author(s) : Gorecki L , Hepnarova V , Karasova JZ , Hrabinova M , Courageux C , Dias J , Kucera T , Kobrlova T , Muckova L , Prchal L , Malinak D , Jun D , Musilek K , Worek F , Nachon F , Soukup O , Korabecny J |
| Ref : Archives of Toxicology , : , 2021 |
| Abstract : |
| PubMedSearch : Gorecki_2021_Arch.Toxicol__ |
| PubMedID: 33517499 |
| Title : Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database - Miles_2021_Chem.Biol.Drug.Des__ |
| Author(s) : Miles JA , Ng JH , Sreenivas BY , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP |
| Ref : Chemical Biology Drug Des , : , 2021 |
| Abstract : |
| PubMedSearch : Miles_2021_Chem.Biol.Drug.Des__ |
| PubMedID: 33455074 |
| Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021 |
| Abstract : |
| PubMedSearch : Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| PubMedID: 33838585 |
| Title : Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability - Yerri_2020_Chemistry_26_15035 |
| Author(s) : Yerri J , Dias J , Nimmakayala MR , Razafindrainibe F , Courageux C , Gastellier AJ , Jegoux J , Coisne C , Landry C , Gosselet F , Hachani J , Goossens JF , Dehouck MP , Nachon F , Baati R |
| Ref : Chemistry , 26 :15035 , 2020 |
| Abstract : |
| PubMedSearch : Yerri_2020_Chemistry_26_15035 |
| PubMedID: 32633095 |
| Title : Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime - Calas_2020_Biomolecules_10_ |
| Author(s) : Calas AG , Hanak AS , Jaffre N , Nervo A , Dias J , Rousseau C , Courageux C , Brazzolotto X , Villa P , Obrecht A , Goossens JF , Landry C , Hachani J , Gosselet F , Dehouck MP , Yerri J , Kliachyna M , Baati R , Nachon F |
| Ref : Biomolecules , 10 : , 2020 |
| Abstract : |
| PubMedSearch : Calas_2020_Biomolecules_10_ |
| PubMedID: 32512884 |
| Title : Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime - Calas_2020_Biomolecules_10_ |
| Author(s) : Calas AG , Hanak AS , Jaffre N , Nervo A , Dias J , Rousseau C , Courageux C , Brazzolotto X , Villa P , Obrecht A , Goossens JF , Landry C , Hachani J , Gosselet F , Dehouck MP , Yerri J , Kliachyna M , Baati R , Nachon F |
| Ref : Biomolecules , 10 : , 2020 |
| Abstract : |
| PubMedSearch : Calas_2020_Biomolecules_10_ |
| PubMedID: 32512884 |
| Title : Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening - Miles_2020_Bioorg.Med.Chem.Lett__127609 |
| Author(s) : Miles JA , Kapure JS , Singh Deora G , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP |
| Ref : Bioorganic & Medicinal Chemistry Lett , :127609 , 2020 |
| Abstract : |
| PubMedSearch : Miles_2020_Bioorg.Med.Chem.Lett__127609 |
| PubMedID: 33039562 |
| Title : Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability - Yerri_2020_Chemistry_26_15035 |
| Author(s) : Yerri J , Dias J , Nimmakayala MR , Razafindrainibe F , Courageux C , Gastellier AJ , Jegoux J , Coisne C , Landry C , Gosselet F , Hachani J , Goossens JF , Dehouck MP , Nachon F , Baati R |
| Ref : Chemistry , 26 :15035 , 2020 |
| Abstract : |
| PubMedSearch : Yerri_2020_Chemistry_26_15035 |
| PubMedID: 32633095 |
| Title : Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability - Yerri_2020_Chemistry_26_15035 |
| Author(s) : Yerri J , Dias J , Nimmakayala MR , Razafindrainibe F , Courageux C , Gastellier AJ , Jegoux J , Coisne C , Landry C , Gosselet F , Hachani J , Goossens JF , Dehouck MP , Nachon F , Baati R |
| Ref : Chemistry , 26 :15035 , 2020 |
| Abstract : |
| PubMedSearch : Yerri_2020_Chemistry_26_15035 |
| PubMedID: 32633095 |
| Title : Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime - Calas_2020_Biomolecules_10_ |
| Author(s) : Calas AG , Hanak AS , Jaffre N , Nervo A , Dias J , Rousseau C , Courageux C , Brazzolotto X , Villa P , Obrecht A , Goossens JF , Landry C , Hachani J , Gosselet F , Dehouck MP , Yerri J , Kliachyna M , Baati R , Nachon F |
| Ref : Biomolecules , 10 : , 2020 |
| Abstract : |
| PubMedSearch : Calas_2020_Biomolecules_10_ |
| PubMedID: 32512884 |
| Title : Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening - Miles_2020_Bioorg.Med.Chem.Lett__127609 |
| Author(s) : Miles JA , Kapure JS , Singh Deora G , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP |
| Ref : Bioorganic & Medicinal Chemistry Lett , :127609 , 2020 |
| Abstract : |
| PubMedSearch : Miles_2020_Bioorg.Med.Chem.Lett__127609 |
| PubMedID: 33039562 |
| Title : Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening - Miles_2020_Bioorg.Med.Chem.Lett__127609 |
| Author(s) : Miles JA , Kapure JS , Singh Deora G , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP |
| Ref : Bioorganic & Medicinal Chemistry Lett , :127609 , 2020 |
| Abstract : |
| PubMedSearch : Miles_2020_Bioorg.Med.Chem.Lett__127609 |
| PubMedID: 33039562 |
| Title : New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease - Zueva_2019_Neuropharmacol_155_131 |
| Author(s) : Zueva IV , Dias J , Lushchekina SV , Semenov VE , Mukhamedyarov MA , Pashirova TN , Babaev VM , Nachon F , Petrova N , Nurullin LF , Zakharova LY , Ilyin VI , Masson P , Petrov KA |
| Ref : Neuropharmacology , 155 :131 , 2019 |
| Abstract : |
| PubMedSearch : Zueva_2019_Neuropharmacol_155_131 |
| PubMedID: 31132435 |
| Gene_locus related to this paper: human-ACHE |
| Title : New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease - Zueva_2019_Neuropharmacol_155_131 |
| Author(s) : Zueva IV , Dias J , Lushchekina SV , Semenov VE , Mukhamedyarov MA , Pashirova TN , Babaev VM , Nachon F , Petrova N , Nurullin LF , Zakharova LY , Ilyin VI , Masson P , Petrov KA |
| Ref : Neuropharmacology , 155 :131 , 2019 |
| Abstract : |
| PubMedSearch : Zueva_2019_Neuropharmacol_155_131 |
| PubMedID: 31132435 |
| Gene_locus related to this paper: human-ACHE |
| Title : New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease - Zueva_2019_Neuropharmacol_155_131 |
| Author(s) : Zueva IV , Dias J , Lushchekina SV , Semenov VE , Mukhamedyarov MA , Pashirova TN , Babaev VM , Nachon F , Petrova N , Nurullin LF , Zakharova LY , Ilyin VI , Masson P , Petrov KA |
| Ref : Neuropharmacology , 155 :131 , 2019 |
| Abstract : |
| PubMedSearch : Zueva_2019_Neuropharmacol_155_131 |
| PubMedID: 31132435 |
| Gene_locus related to this paper: human-ACHE |
| Title : Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents - Santoni_2018_J.Med.Chem_61_7630 |
| Author(s) : Santoni G , de Sousa J , De la Mora E , Dias J , Jean L , Sussman JL , Silman I , Renard PY , Brown RCD , Weik M , Baati R , Nachon F |
| Ref : Journal of Medicinal Chemistry , 61 :7630 , 2018 |
| Abstract : |
| PubMedSearch : Santoni_2018_J.Med.Chem_61_7630 |
| PubMedID: 30125110 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents - Santoni_2018_J.Med.Chem_61_7630 |
| Author(s) : Santoni G , de Sousa J , De la Mora E , Dias J , Jean L , Sussman JL , Silman I , Renard PY , Brown RCD , Weik M , Baati R , Nachon F |
| Ref : Journal of Medicinal Chemistry , 61 :7630 , 2018 |
| Abstract : |
| PubMedSearch : Santoni_2018_J.Med.Chem_61_7630 |
| PubMedID: 30125110 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents - Santoni_2018_J.Med.Chem_61_7630 |
| Author(s) : Santoni G , de Sousa J , De la Mora E , Dias J , Jean L , Sussman JL , Silman I , Renard PY , Brown RCD , Weik M , Baati R , Nachon F |
| Ref : Journal of Medicinal Chemistry , 61 :7630 , 2018 |
| Abstract : |
| PubMedSearch : Santoni_2018_J.Med.Chem_61_7630 |
| PubMedID: 30125110 |
| Gene_locus related to this paper: torca-ACHE |
| Title : An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice - Calas_2017_Chem.Biol.Interact_267_11 |
| Author(s) : Calas AG , Dias J , Rousseau C , Arboleas M , Touvrey-Loiodice M , Mercey G , Jean L , Renard PY , Nachon F |
| Ref : Chemico-Biological Interactions , 267 :11 , 2017 |
| Abstract : |
| PubMedSearch : Calas_2017_Chem.Biol.Interact_267_11 |
| PubMedID: 26972668 |
| Title : An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice - Calas_2017_Chem.Biol.Interact_267_11 |
| Author(s) : Calas AG , Dias J , Rousseau C , Arboleas M , Touvrey-Loiodice M , Mercey G , Jean L , Renard PY , Nachon F |
| Ref : Chemico-Biological Interactions , 267 :11 , 2017 |
| Abstract : |
| PubMedSearch : Calas_2017_Chem.Biol.Interact_267_11 |
| PubMedID: 26972668 |
| Title : An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice - Calas_2017_Chem.Biol.Interact_267_11 |
| Author(s) : Calas AG , Dias J , Rousseau C , Arboleas M , Touvrey-Loiodice M , Mercey G , Jean L , Renard PY , Nachon F |
| Ref : Chemico-Biological Interactions , 267 :11 , 2017 |
| Abstract : |
| PubMedSearch : Calas_2017_Chem.Biol.Interact_267_11 |
| PubMedID: 26972668 |