Title : Quantitative T(2) mapping-based longitudinal assessment of brain injury and therapeutic rescue in the rat following acute organophosphate intoxication - Almeida_2024_Neuropharmacol__109895 |
Author(s) : Almeida AJD , Hobson BA , Saito N , Bruun DA , Porter VA , Harvey DJ , Garbow JR , Chaudhari AJ , Lein PJ |
Ref : Neuropharmacology , :109895 , 2024 |
Abstract : |
PubMedSearch : Almeida_2024_Neuropharmacol__109895 |
PubMedID: 38437913 |
Title : A longitudinal MRI and TSPO PET-based investigation of brain region-specific neuroprotection by diazepam versus midazolam following organophosphate-induced seizures - Hobson_2024_Neuropharmacol__109918 |
Author(s) : Hobson BA , Rowland DR , Dou Y , Saito N , Harmany ZT , Bruun DA , Harvey DJ , Chaudhari A , Garbow JR , Lein PJ |
Ref : Neuropharmacology , :109918 , 2024 |
Abstract : |
PubMedSearch : Hobson_2024_Neuropharmacol__109918 |
PubMedID: 38527652 |
Title : Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate - Andrew_2024_J.Neuroinflammation_21_285 |
Author(s) : Andrew PM , MacMahon JA , Bernardino PN , Tsai YH , Hobson BA , Porter VA , Huddleston SL , Luo AS , Bruun DA , Saito NH , Harvey DJ , Brooks-Kayal A , Chaudhari AJ , Lein PJ |
Ref : J Neuroinflammation , 21 :285 , 2024 |
Abstract : |
PubMedSearch : Andrew_2024_J.Neuroinflammation_21_285 |
PubMedID: 39497181 |
Title : Acute intoxication with diisopropylfluorophosphate promotes cellular senescence in the adult male rat brain - Tsai_2024_Front.Toxicol_6_1360359 |
Author(s) : Tsai YH , Gonzalez EA , Grodzki ACG , Bruun DA , Saito NH , Harvey DJ , Lein PJ |
Ref : Front Toxicol , 6 :1360359 , 2024 |
Abstract : |
PubMedSearch : Tsai_2024_Front.Toxicol_6_1360359 |
PubMedID: 38745692 |
Title : Intraperitoneally injected d11-11(12)-epoxyeicosatrienoic acid is rapidly incorporated and esterified within rat plasma and peripheral tissues but not the brain - Watanabe_2024_Prostaglandins.Leukot.Essent.Fatty.Acids_202_102622 |
Author(s) : Watanabe S , Souza FDC , Kusumoto I , Shen Q , Nitin N , Lein PJ , Taha AY |
Ref : Prostaglandins Leukot Essent Fatty Acids , 202 :102622 , 2024 |
Abstract : |
PubMedSearch : Watanabe_2024_Prostaglandins.Leukot.Essent.Fatty.Acids_202_102622 |
PubMedID: 38954932 |
Title : The alpha4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability - Andrew_2024_Toxics_12_ |
Author(s) : Andrew PM , Feng W , Calsbeek JJ , Antrobus SP , Cherednychenko GA , MacMahon JA , Bernardino PN , Liu X , Harvey DJ , Lein PJ , Pessah IN |
Ref : Toxics , 12 : , 2024 |
Abstract : |
PubMedSearch : Andrew_2024_Toxics_12_ |
PubMedID: 38668486 |
Title : Diisopropylfluorophosphate (DFP) volatizes and cross-contaminates wells in a common 96-well plate format used in zebrafish larvae toxicology studies - Mundy_2022_J.Pharmacol.Toxicol.Methods_115_107173 |
Author(s) : Mundy PC , Mendieta R , Lein PJ |
Ref : Journal of Pharmacological & Toxicological Methods , 115 :107173 , 2022 |
Abstract : |
PubMedSearch : Mundy_2022_J.Pharmacol.Toxicol.Methods_115_107173 |
PubMedID: 35545188 |
Title : Mechanisms of organophosphate neurotoxicity - Tsai_2021_Curr.Opin.Toxicol_26_49 |
Author(s) : Tsai YH , Lein PJ |
Ref : Curr Opin Toxicol , 26 :49 , 2021 |
Abstract : |
PubMedSearch : Tsai_2021_Curr.Opin.Toxicol_26_49 |
PubMedID: 34308007 |
Title : Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats - Gonzalez_2021_Curr.Res.Toxicol_2_341 |
Author(s) : Gonzalez EA , Calsbeek JJ , Tsai YH , Tang MY , Andrew P , Vu J , Berg EL , Saito NH , Harvey DJ , Supasai S , Gurkoff GG , Silverman JL , Lein PJ |
Ref : Curr Res Toxicol , 2 :341 , 2021 |
Abstract : |
PubMedSearch : Gonzalez_2021_Curr.Res.Toxicol_2_341 |
PubMedID: 34622217 |
Title : Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate - Calsbeek_2021_Neurotoxicol__ |
Author(s) : Calsbeek JJ , Gonzalez EA , Bruun DA , Guignet MA , Copping N , Dawson ME , Yu AJ , MacMahon JA , Saito NH , Harvey DJ , Silverman JL , Lein PJ |
Ref : Neurotoxicology , : , 2021 |
Abstract : |
PubMedSearch : Calsbeek_2021_Neurotoxicol__ |
PubMedID: 34509511 |
Title : A national toxicology program systematic review of the evidence for long-term effects after acute exposure to sarin nerve agent - Jett_2020_Crit.Rev.Toxicol__1 |
Author(s) : Jett DA , Sibrizzi CA , Blain RB , Hartman PA , Lein PJ , Taylor KW , Rooney AA |
Ref : Crit Rev Toxicol , :1 , 2020 |
Abstract : |
PubMedSearch : Jett_2020_Crit.Rev.Toxicol__1 |
PubMedID: 32755358 |
Title : Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate - Supasai_2020_Eur.J.Pharmacol__173538 |
Author(s) : Supasai S , Gonzalez EA , Rowland DJ , Hobson B , Bruun DA , Guignet MA , Soares S , Singh V , Wulff H , Saito N , Harvey DJ , Lein PJ |
Ref : European Journal of Pharmacology , :173538 , 2020 |
Abstract : |
PubMedSearch : Supasai_2020_Eur.J.Pharmacol__173538 |
PubMedID: 32898549 |
Title : Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos - Berg_2020_J.Neurodev.Disord_12_40 |
Author(s) : Berg EL , Ching TM , Bruun DA , Rivera JK , Careaga M , Ellegood J , Lerch JP , Wohr M , Lein PJ , Silverman JL |
Ref : J Neurodev Disord , 12 :40 , 2020 |
Abstract : |
PubMedSearch : Berg_2020_J.Neurodev.Disord_12_40 |
PubMedID: 33327943 |
Title : The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity - Gonzalez_2020_Arch.Toxicol__ |
Author(s) : Gonzalez EA , Rindy AC , Guignet MA , Calsbeek JJ , Bruun DA , Dhir A , Andrew P , Saito N , Rowland DJ , Harvey DJ , Rogawski MA , Lein PJ |
Ref : Archives of Toxicology , : , 2020 |
Abstract : |
PubMedSearch : Gonzalez_2020_Arch.Toxicol__ |
PubMedID: 32303805 |
Title : Magnitude of Behavioral Deficits Varies with Job-Related Chlorpyrifos Exposure Levels among Egyptian Pesticide Workers - Kent_2020_Neurotoxicol__ |
Author(s) : Kent Anger W , Farahat FM , Lein PJ , Lasarev MR , Olson JR , Farahat TM , Rohlman DS |
Ref : Neurotoxicology , : , 2020 |
Abstract : |
PubMedSearch : Kent_2020_Neurotoxicol__ |
PubMedID: 32006538 |
Title : Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells - Proskocil_2019_Am.J.Respir.Cell.Mol.Biol_61_620 |
Author(s) : Proskocil BJ , Grodzki ACG , Jacoby DB , Lein PJ , Fryer AD |
Ref : American Journal of Respiratory Cellular & Molecular Biology , 61 :620 , 2019 |
Abstract : |
PubMedSearch : Proskocil_2019_Am.J.Respir.Cell.Mol.Biol_61_620 |
PubMedID: 30978295 |
Title : Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication - Bruun_2019_Neurotoxicol_73_81 |
Author(s) : Bruun DA , Guignet M , Harvey DJ , Lein PJ |
Ref : Neurotoxicology , 73 :81 , 2019 |
Abstract : |
PubMedSearch : Bruun_2019_Neurotoxicol_73_81 |
PubMedID: 30853371 |
Title : The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats - Shaffo_2018_Toxicol.Sci_165_244 |
Author(s) : Shaffo FC , Grodzki AC , Schelegle ES , Lein PJ |
Ref : Toxicol Sci , 165 :244 , 2018 |
Abstract : |
PubMedSearch : Shaffo_2018_Toxicol.Sci_165_244 |
PubMedID: 29939342 |
Title : Editor's Highlight: Spatiotemporal Progression and Remission of Lesions in the Rat Brain Following Acute Intoxication With Diisopropylfluorophosphate - Siso_2017_Toxicol.Sci_157_330 |
Author(s) : Siso S , Hobson BA , Harvey DJ , Bruun DA , Rowland DJ , Garbow JR , Lein PJ |
Ref : Toxicol Sci , 157 :330 , 2017 |
Abstract : |
PubMedSearch : Siso_2017_Toxicol.Sci_157_330 |
PubMedID: 28329845 |
Title : Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication - Flannery_2016_J.Neuroinflammation_13_267 |
Author(s) : Flannery BM , Bruun DA , Rowland DJ , Banks CN , Austin AT , Kukis DL , Li Y , Ford BD , Tancredi DJ , Silverman JL , Cherry SR , Lein PJ |
Ref : J Neuroinflammation , 13 :267 , 2016 |
Abstract : |
PubMedSearch : Flannery_2016_J.Neuroinflammation_13_267 |
PubMedID: 27733171 |
Title : Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides - Lee_2016_Toxicology_340_53 |
Author(s) : Lee YS , Lewis JA , Ippolito DL , Hussainzada N , Lein PJ , Jackson DA , Stallings JD |
Ref : Toxicology , 340 :53 , 2016 |
Abstract : |
PubMedSearch : Lee_2016_Toxicology_340_53 |
PubMedID: 26775027 |
Title : Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds - Voorhees_2016_Front.Neurosci_10_590 |
Author(s) : Voorhees JR , Rohlman DS , Lein PJ , Pieper AA |
Ref : Front Neurosci , 10 :590 , 2016 |
Abstract : |
PubMedSearch : Voorhees_2016_Front.Neurosci_10_590 |
PubMedID: 28149268 |
Title : Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents - Pessah_2016_Ann.N.Y.Acad.Sci_1378_124 |
Author(s) : Pessah IN , Rogawski MA , Tancredi DJ , Wulff H , Zolkowska D , Bruun DA , Hammock BD , Lein PJ |
Ref : Annals of the New York Academy of Sciences , 1378 :124 , 2016 |
Abstract : |
PubMedSearch : Pessah_2016_Ann.N.Y.Acad.Sci_1378_124 |
PubMedID: 27467073 |
Title : Longitudinal assessment of occupational exposures to the organophosphorous insecticides chlorpyrifos and profenofos in Egyptian cotton field workers - Singleton_2015_Int.J.Hyg.Environ.Health_218_203 |
Author(s) : Singleton ST , Lein PJ , Dadson OA , McGarrigle BP , Farahat FM , Farahat T , Bonner MR , Fenske RA , Galvin K , Lasarev MR , Anger WK , Rohlman DS , Olson JR |
Ref : Int J Hyg Environ Health , 218 :203 , 2015 |
Abstract : |
PubMedSearch : Singleton_2015_Int.J.Hyg.Environ.Health_218_203 |
PubMedID: 25466362 |
Title : The Influence of Sensitization on Mechanisms of Organophosphorus Pesticide-Induced Airway Hyperreactivity - Proskocil_2015_Am.J.Respir.Cell.Mol.Biol_53_738 |
Author(s) : Proskocil BJ , Bruun DA , Garg JA , Villagomez CC , Jacoby DB , Lein PJ , Fryer AD |
Ref : American Journal of Respiratory Cellular & Molecular Biology , 53 :738 , 2015 |
Abstract : |
PubMedSearch : Proskocil_2015_Am.J.Respir.Cell.Mol.Biol_53_738 |
PubMedID: 25897622 |
Title : Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication - Vito_2014_Toxicol.Appl.Pharmacol_281_185 |
Author(s) : Vito ST , Austin AT , Banks CN , Inceoglu B , Bruun DA , Zolkowska D , Tancredi DJ , Rogawski MA , Hammock BD , Lein PJ |
Ref : Toxicol Appl Pharmacol , 281 :185 , 2014 |
Abstract : |
PubMedSearch : Vito_2014_Toxicol.Appl.Pharmacol_281_185 |
PubMedID: 25448683 |
Title : Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker - Dadson_2013_Toxicology_306_35 |
Author(s) : Dadson OA , Ellison CA , Singleton ST , Chi LH , McGarrigle BP , Lein PJ , Farahat FM , Farahat T , Olson JR |
Ref : Toxicology , 306 :35 , 2013 |
Abstract : |
PubMedSearch : Dadson_2013_Toxicology_306_35 |
PubMedID: 23415833 |
Title : Neuronal connectivity as a convergent target of gene x environment interactions that confer risk for Autism Spectrum Disorders - Stamou_2013_Neurotoxicol.Teratol_36_3 |
Author(s) : Stamou M , Streifel KM , Goines PE , Lein PJ |
Ref : Neurotoxicology & Teratology , 36 :3 , 2013 |
Abstract : |
PubMedSearch : Stamou_2013_Neurotoxicol.Teratol_36_3 |
PubMedID: 23269408 |
Title : Macrophage TNF-alpha mediates parathion-induced airway hyperreactivity in guinea pigs - Proskocil_2013_Am.J.Physiol.Lung.Cell.Mol.Physiol_304_L519 |
Author(s) : Proskocil BJ , Bruun DA , Jacoby DB , van Rooijen N , Lein PJ , Fryer AD |
Ref : American Journal of Physiology Lung Cell Mol Physiol , 304 :L519 , 2013 |
Abstract : |
PubMedSearch : Proskocil_2013_Am.J.Physiol.Lung.Cell.Mol.Physiol_304_L519 |
PubMedID: 23377347 |
Title : A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation - Banks_2012_Neurotoxicol_33_575 |
Author(s) : Banks CN , Lein PJ |
Ref : Neurotoxicology , 33 :575 , 2012 |
Abstract : |
PubMedSearch : Banks_2012_Neurotoxicol_33_575 |
PubMedID: 22342984 |
Title : Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation - |
Author(s) : Bal-Price AK , Coecke S , Costa L , Crofton KM , Fritsche E , Goldberg A , Grandjean P , Lein PJ , Li A , Lucchini R , Mundy WR , Padilla S , Persico AM , Seiler AE , Kreysa J |
Ref : ALTEX , 29 :202 , 2012 |
PubMedID: 22892558 |
Title : PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos - Ellison_2012_Toxicol.Appl.Pharmacol_265_308 |
Author(s) : Ellison CA , Crane AL , Bonner MR , Knaak JB , Browne RW , Lein PJ , Olson JR |
Ref : Toxicol Appl Pharmacol , 265 :308 , 2012 |
Abstract : |
PubMedSearch : Ellison_2012_Toxicol.Appl.Pharmacol_265_308 |
PubMedID: 22975224 |
Title : Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior - Yang_2011_Toxicol.Sci_121_146 |
Author(s) : Yang D , Lauridsen H , Buels K , Chi LH , La Du J , Bruun DA , Olson JR , Tanguay RL , Lein PJ |
Ref : Toxicol Sci , 121 :146 , 2011 |
Abstract : |
PubMedSearch : Yang_2011_Toxicol.Sci_121_146 |
PubMedID: 21346248 |
Title : Biomarkers of chlorpyrifos exposure and effect in Egyptian cotton field workers - Farahat_2011_Environ.Health.Perspect_119_801 |
Author(s) : Farahat FM , Ellison CA , Bonner MR , McGarrigle BP , Crane AL , Fenske RA , Lasarev MR , Rohlman DS , Anger WK , Lein PJ , Olson JR |
Ref : Environmental Health Perspectives , 119 :801 , 2011 |
Abstract : |
PubMedSearch : Farahat_2011_Environ.Health.Perspect_119_801 |
PubMedID: 21224175 |
Title : Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure - Rohlman_2011_Neurotoxicol_32_268 |
Author(s) : Rohlman DS , Anger WK , Lein PJ |
Ref : Neurotoxicology , 32 :268 , 2011 |
Abstract : |
PubMedSearch : Rohlman_2011_Neurotoxicol_32_268 |
PubMedID: 21182866 |
Title : Organophosphorus pesticides decrease M2 muscarinic receptor function in guinea pig airway nerves via indirect mechanisms - Proskocil_2010_PLoS.One_5_e10562 |
Author(s) : Proskocil BJ , Bruun DA , Thompson CM , Fryer AD , Lein PJ |
Ref : PLoS ONE , 5 :e10562 , 2010 |
Abstract : |
PubMedSearch : Proskocil_2010_PLoS.One_5_e10562 |
PubMedID: 20479945 |
Title : Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity - Proskocil_2008_Environ.Health.Perspect_116_381 |
Author(s) : Proskocil BJ , Bruun DA , Lorton JK , Blensly KC , Jacoby DB , Lein PJ , Fryer AD |
Ref : Environmental Health Perspectives , 116 :381 , 2008 |
Abstract : |
PubMedSearch : Proskocil_2008_Environ.Health.Perspect_116_381 |
PubMedID: 18335107 |
Title : Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase - Yang_2008_Toxicol.Appl.Pharmacol_228_32 |
Author(s) : Yang D , Howard A , Bruun D , Ajua-Alemanj M , Pickart C , Lein PJ |
Ref : Toxicol Appl Pharmacol , 228 :32 , 2008 |
Abstract : |
PubMedSearch : Yang_2008_Toxicol.Appl.Pharmacol_228_32 |
PubMedID: 18076960 |
Title : Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition - Lein_2005_Toxicol.Sci_83_166 |
Author(s) : Lein PJ , Fryer AD |
Ref : Toxicol Sci , 83 :166 , 2005 |
Abstract : |
PubMedSearch : Lein_2005_Toxicol.Sci_83_166 |
PubMedID: 15470232 |
Title : Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures - Howard_2005_Toxicol.Appl.Pharmacol_207_112 |
Author(s) : Howard AS , Bucelli R , Jett DA , Bruun D , Yang D , Lein PJ |
Ref : Toxicol Appl Pharmacol , 207 :112 , 2005 |
Abstract : |
PubMedSearch : Howard_2005_Toxicol.Appl.Pharmacol_207_112 |
PubMedID: 16102564 |
Title : Mechanisms of organophosphate insecticide-induced airway hyperreactivity - Fryer_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L963 |
Author(s) : Fryer AD , Lein PJ , Howard AS , Yost BL , Beckles RA , Jett DA |
Ref : American Journal of Physiology Lung Cell Mol Physiol , 286 :L963 , 2004 |
Abstract : |
PubMedSearch : Fryer_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L963 |
PubMedID: 14704222 |
Title : Noncholinesterase Mechanisms of Chlorpyrifos Neurotoxicity: Altered Phosphorylation of Ca(2+)\/cAMP Response Element Binding Protein in Cultured Neurons - Schuh_2002_Toxicol.Appl.Pharmacol_182_176 |
Author(s) : Schuh RA , Lein PJ , Beckles RA , Jett DA |
Ref : Toxicol Appl Pharmacol , 182 :176 , 2002 |
Abstract : |
PubMedSearch : Schuh_2002_Toxicol.Appl.Pharmacol_182_176 |
PubMedID: 12140181 |