Title : A randomized, placebo-controlled study investigating the nicotinic alpha7 agonist, RG3487, for cognitive deficits in schizophrenia - Umbricht_2014_Neuropsychopharmacology_39_1568 |
Author(s) : Umbricht D , Keefe RS , Murray S , Lowe DA , Porter R , Garibaldi G , Santarelli L |
Ref : Neuropsychopharmacology , 39 :1568 , 2014 |
Abstract : |
PubMedSearch : Umbricht_2014_Neuropsychopharmacology_39_1568 |
PubMedID: 24549101 |
Title : Chemistry and behavioral studies identify chiral cyclopropanes as selective alpha4beta2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile - Zhang_2012_J.Med.Chem_55_717 |
Author(s) : Zhang H , Tuckmantel W , Eaton JB , Yuen PW , Yu LF , Bajjuri KM , Fedolak A , Wang D , Ghavami A , Caldarone B , Paterson NE , Lowe DA , Brunner D , Lukas RJ , Kozikowski AP |
Ref : Journal of Medicinal Chemistry , 55 :717 , 2012 |
Abstract : |
PubMedSearch : Zhang_2012_J.Med.Chem_55_717 |
PubMedID: 22171543 |
Title : RG3487, a novel nicotinic alpha7 receptor partial agonist, improves cognition and sensorimotor gating in rodents - Wallace_2011_J.Pharmacol.Exp.Ther_336_242 |
Author(s) : Wallace TL , Callahan PM , Tehim A , Bertrand D , Tombaugh G , Wang S , Xie W , Rowe WB , Ong V , Graham E , Terry AV, Jr. , Rodefer JS , Herbert B , Murray M , Porter R , Santarelli L , Lowe DA |
Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :242 , 2011 |
Abstract : |
PubMedSearch : Wallace_2011_J.Pharmacol.Exp.Ther_336_242 |
PubMedID: 20959364 |
Title : Discovery of isoxazole analogues of sazetidine-A as selective alpha4beta2-nicotinic acetylcholine receptor partial agonists for the treatment of depression - Liu_2011_J.Med.Chem_54_7280 |
Author(s) : Liu J , Yu LF , Eaton JB , Caldarone B , Cavino K , Ruiz C , Terry M , Fedolak A , Wang D , Ghavami A , Lowe DA , Brunner D , Lukas RJ , Kozikowski AP |
Ref : Journal of Medicinal Chemistry , 54 :7280 , 2011 |
Abstract : |
PubMedSearch : Liu_2011_J.Med.Chem_54_7280 |
PubMedID: 21905669 |
Title : Effect of R3487\/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats - Rezvani_2009_Prog.Neuropsychopharmacol.Biol.Psychiatry_33_269 |
Author(s) : Rezvani AH , Kholdebarin E , Brucato FH , Callahan PM , Lowe DA , Levin ED |
Ref : Prog Neuropsychopharmacol Biological Psychiatry , 33 :269 , 2009 |
Abstract : |
PubMedSearch : Rezvani_2009_Prog.Neuropsychopharmacol.Biol.Psychiatry_33_269 |
PubMedID: 19110025 |
Title : Poster: R3487\/MEM 3454, a novel nicotinic alpha 7 receptor partial agonist, improves attention and working memory performance in cynomolgus macaques - |
Author(s) : Wallace TL , Chiu G , Dao H , Lowe DA , Porter R , Santarelli L |
Ref : Biochemical Pharmacology , 78 :912 , 2009 |
PubMedID: |