| Title : Synthesis and biological evaluation of novel hybrids of highly potent and selective alpha4beta2-Nicotinic acetylcholine receptor (nAChR) partial agonists - Zhang_2016_Eur.J.Med.Chem_124_689 |
| Author(s) : Zhang HK , Eaton JB , Fedolak A , Gunosewoyo H , Onajole OK , Brunner D , Lukas RJ , Yu LF , Kozikowski AP |
| Ref : Eur Journal of Medicinal Chemistry , 124 :689 , 2016 |
| Abstract : |
| PubMedSearch : Zhang_2016_Eur.J.Med.Chem_124_689 |
| PubMedID: 27639361 |
| Title : The unique alpha4(+)\/(-)alpha4 agonist binding site in (alpha4)3(beta2)2 subtype nicotinic acetylcholine receptors permits differential agonist desensitization pharmacology versus the (alpha4)2(beta2)3 subtype - Eaton_2014_J.Pharmacol.Exp.Ther_348_46 |
| Author(s) : Eaton JB , Lucero LM , Stratton H , Chang Y , Cooper JF , Lindstrom JM , Lukas RJ , Whiteaker P |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 348 :46 , 2014 |
| Abstract : |
| PubMedSearch : Eaton_2014_J.Pharmacol.Exp.Ther_348_46 |
| PubMedID: 24190916 |
| Title : Chemistry and behavioral studies identify chiral cyclopropanes as selective alpha4beta2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile - Zhang_2012_J.Med.Chem_55_717 |
| Author(s) : Zhang H , Tuckmantel W , Eaton JB , Yuen PW , Yu LF , Bajjuri KM , Fedolak A , Wang D , Ghavami A , Caldarone B , Paterson NE , Lowe DA , Brunner D , Lukas RJ , Kozikowski AP |
| Ref : Journal of Medicinal Chemistry , 55 :717 , 2012 |
| Abstract : |
| PubMedSearch : Zhang_2012_J.Med.Chem_55_717 |
| PubMedID: 22171543 |
| Title : Discovery of isoxazole analogues of sazetidine-A as selective alpha4beta2-nicotinic acetylcholine receptor partial agonists for the treatment of depression - Liu_2011_J.Med.Chem_54_7280 |
| Author(s) : Liu J , Yu LF , Eaton JB , Caldarone B , Cavino K , Ruiz C , Terry M , Fedolak A , Wang D , Ghavami A , Lowe DA , Brunner D , Lukas RJ , Kozikowski AP |
| Ref : Journal of Medicinal Chemistry , 54 :7280 , 2011 |
| Abstract : |
| PubMedSearch : Liu_2011_J.Med.Chem_54_7280 |
| PubMedID: 21905669 |
| Title : Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine - Carroll_2011_J.Med.Chem_54_1441 |
| Author(s) : Carroll FI , Muresan AZ , Blough BE , Navarro HA , Mascarella SW , Eaton JB , Huang X , Damaj MI , Lukas RJ |
| Ref : Journal of Medicinal Chemistry , 54 :1441 , 2011 |
| Abstract : |
| PubMedSearch : Carroll_2011_J.Med.Chem_54_1441 |
| PubMedID: 21319801 |
| Title : Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation - Lukas_2010_J.Med.Chem_53_4731 |
| Author(s) : Lukas RJ , Muresan AZ , Damaj MI , Blough BE , Huang X , Navarro HA , Mascarella SW , Eaton JB , Marxer-Miller SK , Carroll FI |
| Ref : Journal of Medicinal Chemistry , 53 :4731 , 2010 |
| Abstract : |
| PubMedSearch : Lukas_2010_J.Med.Chem_53_4731 |
| PubMedID: 20509659 |
| Title : Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2beta-substituted tropanes - Carroll_2010_J.Med.Chem_53_8345 |
| Author(s) : Carroll FI , Blough BE , Mascarella SW , Navarro HA , Eaton JB , Lukas RJ , Damaj MI |
| Ref : Journal of Medicinal Chemistry , 53 :8345 , 2010 |
| Abstract : |
| PubMedSearch : Carroll_2010_J.Med.Chem_53_8345 |
| PubMedID: 21058665 |
| Title : Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation - Carroll_2010_J.Med.Chem_53_2204 |
| Author(s) : Carroll FI , Blough BE , Mascarella SW , Navarro HA , Eaton JB , Lukas RJ , Damaj MI |
| Ref : Journal of Medicinal Chemistry , 53 :2204 , 2010 |
| Abstract : |
| PubMedSearch : Carroll_2010_J.Med.Chem_53_2204 |
| PubMedID: 20158204 |
| Title : Roles for nicotinic acetylcholine receptor subunit large cytoplasmic loop sequences in receptor expression and function - Kuo_2005_J.Pharmacol.Exp.Ther_314_455 |
| Author(s) : Kuo YP , Xu L , Eaton JB , Zhao L , Wu J , Lukas RJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 314 :455 , 2005 |
| Abstract : |
| PubMedSearch : Kuo_2005_J.Pharmacol.Exp.Ther_314_455 |
| PubMedID: 15833891 |
| Title : Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors - Damaj_2004_Mol.Pharmacol_66_675 |
| Author(s) : Damaj MI , Carroll FI , Eaton JB , Navarro HA , Blough BE , Mirza S , Lukas RJ , Martin BR |
| Ref : Molecular Pharmacology , 66 :675 , 2004 |
| Abstract : |
| PubMedSearch : Damaj_2004_Mol.Pharmacol_66_675 |
| PubMedID: 15322260 |
| Title : Characterization of human alpha 4 beta 2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cells - Eaton_2003_Mol.Pharmacol_64_1283 |
| Author(s) : Eaton JB , Peng JH , Schroeder KM , George AA , Fryer JD , Krishnan C , Buhlman L , Kuo YP , Steinlein O , Lukas RJ |
| Ref : Molecular Pharmacology , 64 :1283 , 2003 |
| Abstract : |
| PubMedSearch : Eaton_2003_Mol.Pharmacol_64_1283 |
| PubMedID: 14645658 |