| Title : 1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.0(2,6)]heptanes as new potent muscarinic M1 agonists: structure-activity relationship for 3-aryl-2-propyn-1-yloxy and 3-aryl-2-propyn-1-ylthio derivatives - Jeppesen_1999_J.Med.Chem_42_1999 |
| Author(s) : Jeppesen L , Olesen PH , Hansen L , Sheardown MJ , Thomsen C , Rasmussen T , Jensen AF , Christensen MS , Rimvall K , Ward JS , Whitesitt CA , Calligaro DO , Bymaster FP , DeLapp NW , Felder CC , Shannon HE , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 42 :1999 , 1999 |
| Abstract : |
| PubMedSearch : Jeppesen_1999_J.Med.Chem_42_1999 |
| PubMedID: 10354408 |
| Title : Muscarinic agonists with antipsychotic-like activity: structure-activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity - Sauerberg_1998_J.Med.Chem_41_4378 |
| Author(s) : Sauerberg P , Jeppesen L , Olesen PH , Rasmussen T , Swedberg MD , Sheardown MJ , Fink-Jensen A , Thomsen C , Thogersen H , Rimvall K , Ward JS , Calligaro DO , DeLapp NW , Bymaster FP , Shannon HE |
| Ref : Journal of Medicinal Chemistry , 41 :4378 , 1998 |
| Abstract : |
| PubMedSearch : Sauerberg_1998_J.Med.Chem_41_4378 |
| PubMedID: 9784113 |
| Title : Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic m1 receptor activation - Sauerberg_1998_Bioorg.Med.Chem.Lett_8_2897 |
| Author(s) : Sauerberg P , Jeppesen L , Olesen PH , Sheardown MJ , Fink-Jensen A , Rasmussen T , Rimvall K , Shannon HE , Bymaster FP , DeLapp NW , Calligaro DO , Ward JS , Whitesitt CA , Thomsen C |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :2897 , 1998 |
| Abstract : |
| PubMedSearch : Sauerberg_1998_Bioorg.Med.Chem.Lett_8_2897 |
| PubMedID: 9873644 |
| Title : Conformationally constrained analogues of the muscarinic agonist 3-(4-(methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyr idine. Synthesis, receptor affinity, and antinociceptive activity - Sauerberg_1998_J.Med.Chem_41_109 |
| Author(s) : Sauerberg P , Olesen PH , Sheardown MJ , Rimvall K , Thogersen H , Shannon HE , Sawyer BD , Ward JS , Bymaster FP , DeLapp NW , Calligaro DO , Swedberg MD |
| Ref : Journal of Medicinal Chemistry , 41 :109 , 1998 |
| Abstract : |
| PubMedSearch : Sauerberg_1998_J.Med.Chem_41_109 |
| PubMedID: 9438027 |
| Title : Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects - Bymaster_1998_Brain.Res_795_179 |
| Author(s) : Bymaster FP , Carter PA , Peters SC , Zhang W , Ward JS , Mitch CH , Calligaro DO , Whitesitt CA , DeLapp NC , Shannon HE , Rimvall K , Jeppesen L , Sheardown MJ , Fink-Jensen A , Sauerberg P |
| Ref : Brain Research , 795 :179 , 1998 |
| Abstract : |
| PubMedSearch : Bymaster_1998_Brain.Res_795_179 |
| PubMedID: 9622623 |
| Title : In vivo pharmacology of butylthio[2.2.2] (LY297802 \/ NNC11-1053), an orally acting antinociceptive muscarinic agonist - Shannon_1997_Life.Sci_60(13-14)_969 |
| Author(s) : Shannon HE , Womer DE , Bymaster FP , Calligaro DO , DeLapp NC , Mitch CH , Ward JS , Whitesitt CA , Swedberg MD , Sheardown MJ , Fink-Jensen A , Olesen PH , Rimvall K , Sauerberg P |
| Ref : Life Sciences , 60 :969 , 1997 |
| Abstract : |
| PubMedSearch : Shannon_1997_Life.Sci_60(13-14)_969 |
| PubMedID: 9121363 |
| Title : Poster: Conformationally constrained analogs of the muscarinic agonist methylthio-TZTP. Synthesis, receptor affinity and analgesic activity - |
| Author(s) : Sauerberg P , Olesen PH , Thogersen H , Nielsen S , Sheardown MJ , Rimvall K , Shannon HE , Ward JS , Mitch CH , Bymaster FP , Swedberg MD |
| Ref : Life Sciences , 60 :1164 , 1997 |
| PubMedID: |
| Title : Poster: Stimulation of phosphoinositide hydrolysis in vivo by xanomeline and other muscarinic agents - |
| Author(s) : Bymaster FP , Carter PA , Shannon HE , DeLapp NC , Whitesitt CA , Ward JS , Calligaro DO , Mitch CH , Sheardown MJ , Swedberg MD , Rimvall K , Fink-Jensen A , Jeppesen L , Sauerberg P |
| Ref : Life Sciences , 60 :1165 , 1997 |
| PubMedID: |
| Title : Muscarinic receptors on cultured cells of rat hippocampus: cholinergic regulation and presence of subtypes - Rimvall_1989_Eur.J.Pharmacol_160_1 |
| Author(s) : Rimvall K , Keller F , Waser PG |
| Ref : European Journal of Pharmacology , 160 :1 , 1989 |
| Abstract : |
| PubMedSearch : Rimvall_1989_Eur.J.Pharmacol_160_1 |
| PubMedID: 2714354 |
| Title : Choline and acetylcholine metabolism in slice cultures of the newborn rat septum - Keller_1987_Brain.Res_405_305 |
| Author(s) : Keller F , Rimvall K , Waser PG |
| Ref : Brain Research , 405 :305 , 1987 |
| Abstract : |
| PubMedSearch : Keller_1987_Brain.Res_405_305 |
| PubMedID: 3567608 |
| Title : Subtypes of muscarinic receptors in cultured explants of the hippocampus of the rat - Waser_1987_Neuropharmacol_26_1027 |
| Author(s) : Waser PG , Rimvall K |
| Ref : Neuropharmacology , 26 :1027 , 1987 |
| Abstract : |
| PubMedSearch : Waser_1987_Neuropharmacol_26_1027 |
| PubMedID: 3658113 |
| Title : Muscarinic receptors in slice cultures of rat brain - Rimvall_1986_Neuropharmacol_25_221 |
| Author(s) : Rimvall K , Keller F , Waser PG |
| Ref : Neuropharmacology , 25 :221 , 1986 |
| Abstract : |
| PubMedSearch : Rimvall_1986_Neuropharmacol_25_221 |
| PubMedID: 3703172 |
| Title : Development of cholinergic projections in organotypic cultures of rat septum, hippocampus and cerebellum - Rimvall_1985_Brain.Res_351_267 |
| Author(s) : Rimvall K , Keller F , Waser PG |
| Ref : Brain Research , 351 :267 , 1985 |
| Abstract : |
| PubMedSearch : Rimvall_1985_Brain.Res_351_267 |
| PubMedID: 3995351 |
| Title : Slice cultures confirm the presence of cholinergic neurons in the rat habenula - Keller_1984_Neurosci.Lett_52_299 |
| Author(s) : Keller F , Rimvall K , Waser PG |
| Ref : Neuroscience Letters , 52 :299 , 1984 |
| Abstract : |
| PubMedSearch : Keller_1984_Neurosci.Lett_52_299 |
| PubMedID: 6395047 |
| Title : Choline acetyltransferase in organotypic cultures of rat septum and hippocampus - Keller_1983_Neurosci.Lett_42_273 |
| Author(s) : Keller F , Rimvall K , Waser PG |
| Ref : Neuroscience Letters , 42 :273 , 1983 |
| Abstract : |
| PubMedSearch : Keller_1983_Neurosci.Lett_42_273 |
| PubMedID: 6664633 |