| Title : DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson's disease - Yu_2024_Geroscience__ |
| Author(s) : Yu SJ , Wang Y , Shen H , Bae EK , Li Y , Sambamurti K , Tones MA , Zaleska MM , Hoffer BJ , Greig NH |
| Ref : Geroscience , : , 2024 |
| Abstract : |
| PubMedSearch : Yu_2024_Geroscience__ |
| PubMedID: 38563864 |
| Title : Rivastigmine modifies the alpha-secretase pathway and potentially early Alzheimer's disease - Ray_2020_Transl.Psychiatry_10_47 |
| Author(s) : Ray B , Maloney B , Sambamurti K , Karnati HK , Nelson PT , Greig NH , Lahiri DK |
| Ref : Transl Psychiatry , 10 :47 , 2020 |
| Abstract : |
| PubMedSearch : Ray_2020_Transl.Psychiatry_10_47 |
| PubMedID: 32066688 |
| Title : Synthesis of the Alzheimer Drug Posiphen into its Primary Metabolic Products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their Inhibition of Amyloid Precursor Protein, alpha -Synuclein Synthesis, Interleukin-1beta Release, and Cholinergic Action - Yu_2013_Antiinflamm.Antiallergy.Agents.Med.Chem_12_117 |
| Author(s) : Yu QS , Reale M , Kamal MA , Holloway HW , Luo W , Sambamurti K , Ray B , Lahiri DK , Rogers JT , Greig NH |
| Ref : Antiinflamm Antiallergy Agents Med Chem , 12 :117 , 2013 |
| Abstract : |
| PubMedSearch : Yu_2013_Antiinflamm.Antiallergy.Agents.Med.Chem_12_117 |
| PubMedID: 23360256 |
| Title : The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice - Lahiri_2007_J.Pharmacol.Exp.Ther_320_386 |
| Author(s) : Lahiri DK , Chen D , Maloney B , Holloway HW , Yu QS , Utsuki T , Giordano T , Sambamurti K , Greig NH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 320 :386 , 2007 |
| Abstract : |
| PubMedSearch : Lahiri_2007_J.Pharmacol.Exp.Ther_320_386 |
| PubMedID: 17003227 |
| Title : Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide - Utsuki_2006_J.Pharmacol.Exp.Ther_318_855 |
| Author(s) : Utsuki T , Yu QS , Davidson D , Chen D , Holloway HW , Brossi A , Sambamurti K , Lahiri DK , Greig NH , Giordano T |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 318 :855 , 2006 |
| Abstract : |
| PubMedSearch : Utsuki_2006_J.Pharmacol.Exp.Ther_318_855 |
| PubMedID: 16690718 |
| Title : Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent - Greig_2005_Proc.Natl.Acad.Sci.U.S.A_102_17213 |
| Author(s) : Greig NH , Utsuki T , Ingram DK , Wang Y , Pepeu G , Scali C , Yu QS , Mamczarz J , Holloway HW , Giordano T , Chen D , Furukawa K , Sambamurti K , Brossi A , Lahiri DK |
| Ref : Proc Natl Acad Sci U S A , 102 :17213 , 2005 |
| Abstract : |
| PubMedSearch : Greig_2005_Proc.Natl.Acad.Sci.U.S.A_102_17213 |
| PubMedID: 16275899 |
| Title : An overview of phenserine tartrate, a novel acetylcholinesterase inhibitor for the treatment of Alzheimer's disease - Greig_2005_Curr.Alzheimer.Res_2_281 |
| Author(s) : Greig NH , Sambamurti K , Yu QS , Brossi A , Bruinsma GB , Lahiri DK |
| Ref : Curr Alzheimer Res , 2 :281 , 2005 |
| Abstract : |
| PubMedSearch : Greig_2005_Curr.Alzheimer.Res_2_281 |
| PubMedID: 15974893 |
| Title : Poster (39) A new generation of cholinesterase inhibitors with amyloid-modifying properties. - |
| Author(s) : Lahiri DK , Ge YW , Sambamurti K , Utsuki T , Ingram DK , Farlow MR , Greig NH |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :341 , 2004 |
| PubMedID: |
| Title : Poster (43) BChE inhibition as a treatment strategy for alzheimer's disease. - |
| Author(s) : Greig NH , Ingram DK , Yu QS , Holloway HW , Utsuki T , Brossi A , Sambamurti K , Lahiri DK |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :343 , 2004 |
| PubMedID: |
| Title : Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents - Lahiri_2004_Curr.Pharm.Des_10_3111 |
| Author(s) : Lahiri DK , Rogers JT , Greig NH , Sambamurti K |
| Ref : Curr Pharm Des , 10 :3111 , 2004 |
| Abstract : |
| PubMedSearch : Lahiri_2004_Curr.Pharm.Des_10_3111 |
| PubMedID: 15544501 |
| Title : A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease - Lahiri_2003_Curr.Drug.Targets_4_97 |
| Author(s) : Lahiri DK , Farlow MR , Sambamurti K , Greig NH , Giacobini E , Schneider LS |
| Ref : Curr Drug Targets , 4 :97 , 2003 |
| Abstract : |
| PubMedSearch : Lahiri_2003_Curr.Drug.Targets_4_97 |
| PubMedID: 12558063 |
| Title : Butyrylcholinesterase: an important new target in Alzheimer's disease therapy - Greig_2002_Int.Psychogeriatr_14_77 |
| Author(s) : Greig NH , Lahiri DK , Sambamurti K |
| Ref : Int Psychogeriatr , 14 :77 , 2002 |
| Abstract : |
| PubMedSearch : Greig_2002_Int.Psychogeriatr_14_77 |
| PubMedID: 12636181 |
| Title : Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development - Shaw_2001_Proc.Natl.Acad.Sci.U.S.A_98_7605 |
| Author(s) : Shaw KT , Utsuki T , Rogers J , Yu QS , Sambamurti K , Brossi A , Ge YW , Lahiri DK , Greig NH |
| Ref : Proc Natl Acad Sci U S A , 98 :7605 , 2001 |
| Abstract : |
| PubMedSearch : Shaw_2001_Proc.Natl.Acad.Sci.U.S.A_98_7605 |
| PubMedID: 11404470 |
| Title : The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells - Lahiri_1998_Brain.Res.Mol.Brain.Res_62_131 |
| Author(s) : Lahiri DK , Farlow MR , Sambamurti K |
| Ref : Brain Research Mol Brain Res , 62 :131 , 1998 |
| Abstract : |
| PubMedSearch : Lahiri_1998_Brain.Res.Mol.Brain.Res_62_131 |
| PubMedID: 9813282 |
| Title : The effect of tacrine and leupeptin on the secretion of the beta- amyloid precursor protein in HeLa cells - Lahiri_1997_Life.Sci_61_1985 |
| Author(s) : Lahiri DK , Farlow MR , Sambamurti K , Nall C |
| Ref : Life Sciences , 61 :1985 , 1997 |
| Abstract : |
| PubMedSearch : Lahiri_1997_Life.Sci_61_1985 |
| PubMedID: 9366505 |