| Title : Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy - Utsuki_2007_J.Pharmacol.Exp.Ther_321_353 |
| Author(s) : Utsuki T , Uchimura N , Irikura M , Moriuchi H , Holloway HW , Yu QS , Spangler EL , Mamczarz J , Ingram DK , Irie T , Greig NH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 321 :353 , 2007 |
| Abstract : |
| PubMedSearch : Utsuki_2007_J.Pharmacol.Exp.Ther_321_353 |
| PubMedID: 17255466 |
| Title : The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice - Lahiri_2007_J.Pharmacol.Exp.Ther_320_386 |
| Author(s) : Lahiri DK , Chen D , Maloney B , Holloway HW , Yu QS , Utsuki T , Giordano T , Sambamurti K , Greig NH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 320 :386 , 2007 |
| Abstract : |
| PubMedSearch : Lahiri_2007_J.Pharmacol.Exp.Ther_320_386 |
| PubMedID: 17003227 |
| Title : Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide - Utsuki_2006_J.Pharmacol.Exp.Ther_318_855 |
| Author(s) : Utsuki T , Yu QS , Davidson D , Chen D , Holloway HW , Brossi A , Sambamurti K , Lahiri DK , Greig NH , Giordano T |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 318 :855 , 2006 |
| Abstract : |
| PubMedSearch : Utsuki_2006_J.Pharmacol.Exp.Ther_318_855 |
| PubMedID: 16690718 |
| Title : Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent - Greig_2005_Proc.Natl.Acad.Sci.U.S.A_102_17213 |
| Author(s) : Greig NH , Utsuki T , Ingram DK , Wang Y , Pepeu G , Scali C , Yu QS , Mamczarz J , Holloway HW , Giordano T , Chen D , Furukawa K , Sambamurti K , Brossi A , Lahiri DK |
| Ref : Proc Natl Acad Sci U S A , 102 :17213 , 2005 |
| Abstract : |
| PubMedSearch : Greig_2005_Proc.Natl.Acad.Sci.U.S.A_102_17213 |
| PubMedID: 16275899 |
| Title : Poster (39) A new generation of cholinesterase inhibitors with amyloid-modifying properties. - |
| Author(s) : Lahiri DK , Ge YW , Sambamurti K , Utsuki T , Ingram DK , Farlow MR , Greig NH |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :341 , 2004 |
| PubMedID: |
| Title : Poster (43) BChE inhibition as a treatment strategy for alzheimer's disease. - |
| Author(s) : Greig NH , Ingram DK , Yu QS , Holloway HW , Utsuki T , Brossi A , Sambamurti K , Lahiri DK |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :343 , 2004 |
| PubMedID: |
| Title : Nicotine reduces the secretion of Alzheimer's beta-amyloid precursor protein containing beta-amyloid peptide in the rat without altering synaptic proteins - Lahiri_2002_Ann.N.Y.Acad.Sci_965_364 |
| Author(s) : Lahiri DK , Utsuki T , Chen D , Farlow MR , Shoaib M , Ingram DK , Greig NH |
| Ref : Annals of the New York Academy of Sciences , 965 :364 , 2002 |
| Abstract : |
| PubMedSearch : Lahiri_2002_Ann.N.Y.Acad.Sci_965_364 |
| PubMedID: 12105112 |
| Title : A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase - Greig_2001_Curr.Med.Res.Opin_17_159 |
| Author(s) : Greig NH , Utsuki T , Yu Q , Zhu X , Holloway HW , Perry T , Lee B , Ingram DK , Lahiri DK |
| Ref : Curr Med Res Opin , 17 :159 , 2001 |
| Abstract : |
| PubMedSearch : Greig_2001_Curr.Med.Res.Opin_17_159 |
| PubMedID: 11900310 |
| Title : Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development - Shaw_2001_Proc.Natl.Acad.Sci.U.S.A_98_7605 |
| Author(s) : Shaw KT , Utsuki T , Rogers J , Yu QS , Sambamurti K , Brossi A , Ge YW , Lahiri DK , Greig NH |
| Ref : Proc Natl Acad Sci U S A , 98 :7605 , 2001 |
| Abstract : |
| PubMedSearch : Shaw_2001_Proc.Natl.Acad.Sci.U.S.A_98_7605 |
| PubMedID: 11404470 |
| Title : Cholinesterase inhibitors, beta-amyloid precursor protein and amyloid beta-peptides in Alzheimer's disease - Lahiri_2000_Acta.Neurol.Scand.Suppl_176_60 |
| Author(s) : Lahiri DK , Farlow MR , Hintz N , Utsuki T , Greig NH |
| Ref : Acta Neurologica Scandinavica Supplementum , 176 :60 , 2000 |
| Abstract : |
| PubMedSearch : Lahiri_2000_Acta.Neurol.Scand.Suppl_176_60 |
| PubMedID: 11273593 |
| Title : The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics - Greig_2000_Acta.Neurol.Scand.Suppl_176_74 |
| Author(s) : Greig NH , De Micheli E , Holloway HW , Yu QS , Utsuki T , Perry TA , Brossi A , Ingram DK , Deutsch J , Lahiri DK , Soncrant TT |
| Ref : Acta Neurologica Scandinavica Supplementum , 176 :74 , 2000 |
| Abstract : |
| PubMedSearch : Greig_2000_Acta.Neurol.Scand.Suppl_176_74 |
| PubMedID: 11261809 |
| Title : Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease - Yu_1999_J.Med.Chem_42_1855 |
| Author(s) : Yu Q , Holloway HW , Utsuki T , Brossi A , Greig NH |
| Ref : Journal of Medicinal Chemistry , 42 :1855 , 1999 |
| Abstract : |
| PubMedSearch : Yu_1999_J.Med.Chem_42_1855 |
| PubMedID: 10346939 |
| Title : Pharmacological modulation of Alzheimer's beta-amyloid precursor protein levels in the CSF of rats with forebrain cholinergic system lesions - Haroutunian_1997_Brain.Res.Mol.Brain.Res_46_161 |
| Author(s) : Haroutunian V , Greig N , Pei XF , Utsuki T , Gluck R , Acevedo LD , Davis KL , Wallace WC |
| Ref : Brain Research Mol Brain Res , 46 :161 , 1997 |
| Abstract : |
| PubMedSearch : Haroutunian_1997_Brain.Res.Mol.Brain.Res_46_161 |
| PubMedID: 9191090 |