Full name : Lahiri Debomoy K
First name : Debomoy K
Mail : University School of Medicine 791 Union Drive, Indianapolis IN 46202
Zip Code :
City :
Country : USA
Email : dlahiri@iupui.edu
Phone : 317 274 2706
Fax : 317 274 1365
Website :
Directory :
Comment
| Title : Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders - Li_2024_Geroscience__ |
| Author(s) : Li Y , Vaughan KL , Wang Y , Yu SJ , Bae EK , Tamargo IA , Kopp KO , Tweedie D , Chiang CC , Schmidt KT , Lahiri DK , Tones MA , Zaleska MM , Hoffer BJ , Mattison JA , Greig NH |
| Ref : Geroscience , : , 2024 |
| Abstract : |
| PubMedSearch : Li_2024_Geroscience__ |
| PubMedID: 38532069 |
| Title : Negative and positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor regulates the ability of adolescent binge alcohol exposure to enhance adult alcohol consumption - Rodd_2022_Front.Behav.Neurosci_16_954319 |
| Author(s) : Rodd ZA , Swartzwelder HS , Waeiss RA , Soloviov SO , Lahiri DK , Engleman EA , Truitt WA , Bell RL , Hauser SR |
| Ref : Front Behavioral Neuroscience , 16 :954319 , 2022 |
| Abstract : |
| PubMedSearch : Rodd_2022_Front.Behav.Neurosci_16_954319 |
| PubMedID: 37082421 |
| Title : Rivastigmine modifies the alpha-secretase pathway and potentially early Alzheimer's disease - Ray_2020_Transl.Psychiatry_10_47 |
| Author(s) : Ray B , Maloney B , Sambamurti K , Karnati HK , Nelson PT , Greig NH , Lahiri DK |
| Ref : Transl Psychiatry , 10 :47 , 2020 |
| Abstract : |
| PubMedSearch : Ray_2020_Transl.Psychiatry_10_47 |
| PubMedID: 32066688 |
| Title : Selective Acetyl- and Butyrylcholinesterase Inhibitors Reduce Amyloid-beta Ex Vivo Activation of Peripheral Chemo-cytokines From Alzheimer's Disease Subjects: Exploring the Cholinergic Anti-inflammatory Pathway - Reale_2014_Curr.Alzheimer.Res_11_608 |
| Author(s) : Reale M , Di Nicola M , Velluto L , D'Angelo C , Costantini E , Lahiri DK , Kamal MA , Yu QS , Greig NH |
| Ref : Curr Alzheimer Res , 11 :608 , 2014 |
| Abstract : |
| PubMedSearch : Reale_2014_Curr.Alzheimer.Res_11_608 |
| PubMedID: 24359497 |
| Title : Synthesis of the Alzheimer Drug Posiphen into its Primary Metabolic Products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their Inhibition of Amyloid Precursor Protein, alpha -Synuclein Synthesis, Interleukin-1beta Release, and Cholinergic Action - Yu_2013_Antiinflamm.Antiallergy.Agents.Med.Chem_12_117 |
| Author(s) : Yu QS , Reale M , Kamal MA , Holloway HW , Luo W , Sambamurti K , Ray B , Lahiri DK , Rogers JT , Greig NH |
| Ref : Antiinflamm Antiallergy Agents Med Chem , 12 :117 , 2013 |
| Abstract : |
| PubMedSearch : Yu_2013_Antiinflamm.Antiallergy.Agents.Med.Chem_12_117 |
| PubMedID: 23360256 |
| Title : The aged garlic extract: (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer's disease (AD) - Ray_2011_Curr.Med.Chem_18_3306 |
| Author(s) : Ray B , Chauhan NB , Lahiri DK |
| Ref : Curr Med Chem , 18 :3306 , 2011 |
| Abstract : |
| PubMedSearch : Ray_2011_Curr.Med.Chem_18_3306 |
| PubMedID: 21728972 |
| Title : Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model - Ray_2011_J.Neurochem_117_388 |
| Author(s) : Ray B , Chauhan NB , Lahiri DK |
| Ref : Journal of Neurochemistry , 117 :388 , 2011 |
| Abstract : |
| PubMedSearch : Ray_2011_J.Neurochem_117_388 |
| PubMedID: 21166677 |
| Title : A novel effect of rivastigmine on pre-synaptic proteins and neuronal viability in a neurodegeneration model of fetal rat primary cortical cultures and its implication in Alzheimer's disease - Bailey_2010_J.Neurochem_112_843 |
| Author(s) : Bailey JA , Lahiri DK |
| Ref : Journal of Neurochemistry , 112 :843 , 2010 |
| Abstract : |
| PubMedSearch : Bailey_2010_J.Neurochem_112_843 |
| PubMedID: 19912467 |
| Title : Long-acting anticholinesterases for myasthenia gravis: synthesis and activities of quaternary phenylcarbamates of neostigmine, pyridostigmine and physostigmine - Yu_2010_Bioorg.Med.Chem_18_4687 |
| Author(s) : Yu QS , Holloway HW , Luo W , Lahiri DK , Brossi A , Greig NH |
| Ref : Bioorganic & Medicinal Chemistry , 18 :4687 , 2010 |
| Abstract : |
| PubMedSearch : Yu_2010_Bioorg.Med.Chem_18_4687 |
| PubMedID: 20627738 |
| Title : The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice - Lahiri_2007_J.Pharmacol.Exp.Ther_320_386 |
| Author(s) : Lahiri DK , Chen D , Maloney B , Holloway HW , Yu QS , Utsuki T , Giordano T , Sambamurti K , Greig NH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 320 :386 , 2007 |
| Abstract : |
| PubMedSearch : Lahiri_2007_J.Pharmacol.Exp.Ther_320_386 |
| PubMedID: 17003227 |
| Title : Differential effects of two hexahydropyrroloindole carbamate-based anticholinesterase drugs on the amyloid beta protein pathway involved in Alzheimer's disease - Lahiri_2007_Neuromolecular.Med_9_157 |
| Author(s) : Lahiri DK , Alley GM , Tweedie D , Chen D , Greig NH |
| Ref : Neuromolecular Med , 9 :157 , 2007 |
| Abstract : |
| PubMedSearch : Lahiri_2007_Neuromolecular.Med_9_157 |
| PubMedID: 17627035 |
| Title : Neuropathological and immunochemical studies of brain parenchyma in acetylcholinesterase knockout mice: implications in Alzheimer's disease - Rice_2007_J.Alzheimers.Dis_11_481 |
| Author(s) : Rice SG , Nowak L , Duysen EG , Lockridge O , Lahiri DK , Reyes PF |
| Ref : J Alzheimers Dis , 11 :481 , 2007 |
| Abstract : |
| PubMedSearch : Rice_2007_J.Alzheimers.Dis_11_481 |
| PubMedID: 17656828 |
| Title : High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression - Sokol_2006_J.Child.Neurol_21_444 |
| Author(s) : Sokol DK , Chen D , Farlow MR , Dunn DW , Maloney B , Zimmer JA , Lahiri DK |
| Ref : Journal of Child Neurology , 21 :444 , 2006 |
| Abstract : |
| PubMedSearch : Sokol_2006_J.Child.Neurol_21_444 |
| PubMedID: 16948926 |
| Title : Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide - Utsuki_2006_J.Pharmacol.Exp.Ther_318_855 |
| Author(s) : Utsuki T , Yu QS , Davidson D , Chen D , Holloway HW , Brossi A , Sambamurti K , Lahiri DK , Greig NH , Giordano T |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 318 :855 , 2006 |
| Abstract : |
| PubMedSearch : Utsuki_2006_J.Pharmacol.Exp.Ther_318_855 |
| PubMedID: 16690718 |
| Title : Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine - Luo_2006_J.Med.Chem_49_2174 |
| Author(s) : Luo W , Yu QS , Kulkarni SS , Parrish DA , Holloway HW , Tweedie D , Shafferman A , Lahiri DK , Brossi A , Greig NH |
| Ref : Journal of Medicinal Chemistry , 49 :2174 , 2006 |
| Abstract : |
| PubMedSearch : Luo_2006_J.Med.Chem_49_2174 |
| PubMedID: 16570913 |
| Title : Amyloid, cholinesterase, melatonin, and metals and their roles in aging and neurodegenerative diseases - Lahiri_2005_Ann.N.Y.Acad.Sci_1056_430 |
| Author(s) : Lahiri DK , Chen DM , Lahiri P , Bondy S , Greig NH |
| Ref : Annals of the New York Academy of Sciences , 1056 :430 , 2005 |
| Abstract : |
| PubMedSearch : Lahiri_2005_Ann.N.Y.Acad.Sci_1056_430 |
| PubMedID: 16387707 |
| Title : Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent - Greig_2005_Proc.Natl.Acad.Sci.U.S.A_102_17213 |
| Author(s) : Greig NH , Utsuki T , Ingram DK , Wang Y , Pepeu G , Scali C , Yu QS , Mamczarz J , Holloway HW , Giordano T , Chen D , Furukawa K , Sambamurti K , Brossi A , Lahiri DK |
| Ref : Proc Natl Acad Sci U S A , 102 :17213 , 2005 |
| Abstract : |
| PubMedSearch : Greig_2005_Proc.Natl.Acad.Sci.U.S.A_102_17213 |
| PubMedID: 16275899 |
| Title : An overview of phenserine tartrate, a novel acetylcholinesterase inhibitor for the treatment of Alzheimer's disease - Greig_2005_Curr.Alzheimer.Res_2_281 |
| Author(s) : Greig NH , Sambamurti K , Yu QS , Brossi A , Bruinsma GB , Lahiri DK |
| Ref : Curr Alzheimer Res , 2 :281 , 2005 |
| Abstract : |
| PubMedSearch : Greig_2005_Curr.Alzheimer.Res_2_281 |
| PubMedID: 15974893 |
| Title : Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine - Luo_2005_J.Med.Chem_48_986 |
| Author(s) : Luo W , Yu QS , Zhan M , Parrish D , Deschamps JR , Kulkarni SS , Holloway HW , Alley GM , Lahiri DK , Brossi A , Greig NH |
| Ref : Journal of Medicinal Chemistry , 48 :986 , 2005 |
| Abstract : |
| PubMedSearch : Luo_2005_J.Med.Chem_48_986 |
| PubMedID: 15715468 |
| Title : Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents - Lahiri_2004_Curr.Pharm.Des_10_3111 |
| Author(s) : Lahiri DK , Rogers JT , Greig NH , Sambamurti K |
| Ref : Curr Pharm Des , 10 :3111 , 2004 |
| Abstract : |
| PubMedSearch : Lahiri_2004_Curr.Pharm.Des_10_3111 |
| PubMedID: 15544501 |
| Title : Poster (39) A new generation of cholinesterase inhibitors with amyloid-modifying properties. - |
| Author(s) : Lahiri DK , Ge YW , Sambamurti K , Utsuki T , Ingram DK , Farlow MR , Greig NH |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :341 , 2004 |
| PubMedID: |
| Title : Poster (43) BChE inhibition as a treatment strategy for alzheimer's disease. - |
| Author(s) : Greig NH , Ingram DK , Yu QS , Holloway HW , Utsuki T , Brossi A , Sambamurti K , Lahiri DK |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :343 , 2004 |
| PubMedID: |
| Title : A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease - Lahiri_2003_Curr.Drug.Targets_4_97 |
| Author(s) : Lahiri DK , Farlow MR , Sambamurti K , Greig NH , Giacobini E , Schneider LS |
| Ref : Curr Drug Targets , 4 :97 , 2003 |
| Abstract : |
| PubMedSearch : Lahiri_2003_Curr.Drug.Targets_4_97 |
| PubMedID: 12558063 |
| Title : Nicotine reduces the secretion of Alzheimer's beta-amyloid precursor protein containing beta-amyloid peptide in the rat without altering synaptic proteins - Lahiri_2002_Ann.N.Y.Acad.Sci_965_364 |
| Author(s) : Lahiri DK , Utsuki T , Chen D , Farlow MR , Shoaib M , Ingram DK , Greig NH |
| Ref : Annals of the New York Academy of Sciences , 965 :364 , 2002 |
| Abstract : |
| PubMedSearch : Lahiri_2002_Ann.N.Y.Acad.Sci_965_364 |
| PubMedID: 12105112 |
| Title : Butyrylcholinesterase: an important new target in Alzheimer's disease therapy - Greig_2002_Int.Psychogeriatr_14_77 |
| Author(s) : Greig NH , Lahiri DK , Sambamurti K |
| Ref : Int Psychogeriatr , 14 :77 , 2002 |
| Abstract : |
| PubMedSearch : Greig_2002_Int.Psychogeriatr_14_77 |
| PubMedID: 12636181 |
| Title : Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development - Shaw_2001_Proc.Natl.Acad.Sci.U.S.A_98_7605 |
| Author(s) : Shaw KT , Utsuki T , Rogers J , Yu QS , Sambamurti K , Brossi A , Ge YW , Lahiri DK , Greig NH |
| Ref : Proc Natl Acad Sci U S A , 98 :7605 , 2001 |
| Abstract : |
| PubMedSearch : Shaw_2001_Proc.Natl.Acad.Sci.U.S.A_98_7605 |
| PubMedID: 11404470 |
| Title : A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase - Greig_2001_Curr.Med.Res.Opin_17_159 |
| Author(s) : Greig NH , Utsuki T , Yu Q , Zhu X , Holloway HW , Perry T , Lee B , Ingram DK , Lahiri DK |
| Ref : Curr Med Res Opin , 17 :159 , 2001 |
| Abstract : |
| PubMedSearch : Greig_2001_Curr.Med.Res.Opin_17_159 |
| PubMedID: 11900310 |
| Title : Cholinesterase inhibitors, beta-amyloid precursor protein and amyloid beta-peptides in Alzheimer's disease - Lahiri_2000_Acta.Neurol.Scand.Suppl_176_60 |
| Author(s) : Lahiri DK , Farlow MR , Hintz N , Utsuki T , Greig NH |
| Ref : Acta Neurologica Scandinavica Supplementum , 176 :60 , 2000 |
| Abstract : |
| PubMedSearch : Lahiri_2000_Acta.Neurol.Scand.Suppl_176_60 |
| PubMedID: 11273593 |
| Title : The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics - Greig_2000_Acta.Neurol.Scand.Suppl_176_74 |
| Author(s) : Greig NH , De Micheli E , Holloway HW , Yu QS , Utsuki T , Perry TA , Brossi A , Ingram DK , Deutsch J , Lahiri DK , Soncrant TT |
| Ref : Acta Neurologica Scandinavica Supplementum , 176 :74 , 2000 |
| Abstract : |
| PubMedSearch : Greig_2000_Acta.Neurol.Scand.Suppl_176_74 |
| PubMedID: 11261809 |
| Title : Metrifonate treatment of AD: influence of APOE genotype - Farlow_1999_Neurology_53_2010 |
| Author(s) : Farlow MR , Cyrus PA , Nadel A , Lahiri DK , Brashear A , Gulanski B |
| Ref : Neurology , 53 :2010 , 1999 |
| Abstract : |
| PubMedSearch : Farlow_1999_Neurology_53_2010 |
| PubMedID: 10599773 |
| Title : The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells - Lahiri_1998_Brain.Res.Mol.Brain.Res_62_131 |
| Author(s) : Lahiri DK , Farlow MR , Sambamurti K |
| Ref : Brain Research Mol Brain Res , 62 :131 , 1998 |
| Abstract : |
| PubMedSearch : Lahiri_1998_Brain.Res.Mol.Brain.Res_62_131 |
| PubMedID: 9813282 |
| Title : Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease - Farlow_1998_Neurology_50_669 |
| Author(s) : Farlow MR , Lahiri DK , Poirier J , Davignon J , Schneider L , Hui SL |
| Ref : Neurology , 50 :669 , 1998 |
| Abstract : |
| PubMedSearch : Farlow_1998_Neurology_50_669 |
| PubMedID: 9521254 |
| Title : Effects of cholinesterase inhibitors on the secretion of beta-amyloid precursor protein in cell cultures - Lahiri_1997_Ann.N.Y.Acad.Sci_826_416 |
| Author(s) : Lahiri DK , Farlow MR , Nurnberger JI, Jr. , Greig NH |
| Ref : Annals of the New York Academy of Sciences , 826 :416 , 1997 |
| Abstract : |
| PubMedSearch : Lahiri_1997_Ann.N.Y.Acad.Sci_826_416 |
| PubMedID: 9329715 |
| Title : The effect of tacrine and leupeptin on the secretion of the beta- amyloid precursor protein in HeLa cells - Lahiri_1997_Life.Sci_61_1985 |
| Author(s) : Lahiri DK , Farlow MR , Sambamurti K , Nall C |
| Ref : Life Sciences , 61 :1985 , 1997 |
| Abstract : |
| PubMedSearch : Lahiri_1997_Life.Sci_61_1985 |
| PubMedID: 9366505 |
| Title : Differential effect of tacrine and physostigmine on the secretion of the beta-amyloid precursor protein in cell lines - Lahiri_1996_J.Mol.Neurosci_7_41 |
| Author(s) : Lahiri DK , Farlow MR |
| Ref : Journal of Molecular Neuroscience , 7 :41 , 1996 |
| Abstract : |
| PubMedSearch : Lahiri_1996_J.Mol.Neurosci_7_41 |
| PubMedID: 8835781 |
| Title : Apolipoprotein E genotype and gender influence response to tacrine therapy - Farlow_1996_Ann.N.Y.Acad.Sci_802_101 |
| Author(s) : Farlow MR , Lahiri DK , Poirier J , Davignon J , Hui S |
| Ref : Annals of the New York Academy of Sciences , 802 :101 , 1996 |
| Abstract : |
| PubMedSearch : Farlow_1996_Ann.N.Y.Acad.Sci_802_101 |
| PubMedID: 8993489 |
| Title : Reversibility of the effect of tacrine on the secretion of the beta-amyloid precursor protein in cultured cells - Lahiri_1994_Neurosci.Lett_181_149 |
| Author(s) : Lahiri DK |
| Ref : Neuroscience Letters , 181 :149 , 1994 |
| Abstract : |
| PubMedSearch : Lahiri_1994_Neurosci.Lett_181_149 |
| PubMedID: 7898757 |
| Title : Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines - Lahiri_1994_J.Neurosci.Res_37_777 |
| Author(s) : Lahiri DK , Lewis S , Farlow MR |
| Ref : Journal of Neuroscience Research , 37 :777 , 1994 |
| Abstract : |
| PubMedSearch : Lahiri_1994_J.Neurosci.Res_37_777 |
| PubMedID: 8046778 |