Full name : Giacobini Ezio
First name : Ezio
Mail : Department of Rehabilitation and Geriatrics\; University of Geneva\; Medical School\;Chemin du Pont-Bochet 3, Thonex\; Geneva
Zip Code :
City :
Country : Switzerland
Email : ezio.giacobini@bluewin.ch
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Website :
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Comment
Title : A brief history of the CNS cholinergic transmission - Cuello_2025_Handb.Clin.Neurol_211_1 |
Author(s) : Cuello AC , Giacobini E |
Ref : Handb Clin Neurol , 211 :1 , 2025 |
Abstract : |
PubMedSearch : Cuello_2025_Handb.Clin.Neurol_211_1 |
PubMedID: 40340055 |
Title : Reimagining cholinergic therapy for Alzheimer's disease - Giacobini_2022_Brain_145_2250 |
Author(s) : Giacobini E , Cuello AC , Fisher A |
Ref : Brain , 145 :2250 , 2022 |
Abstract : |
PubMedSearch : Giacobini_2022_Brain_145_2250 |
PubMedID: 35289363 |
Title : Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research - Hampel_2019_J.Prev.Alzheimers.Dis_6_2 |
Author(s) : Hampel H , Mesulam MM , Cuello AC , Khachaturian AS , Vergallo A , Farlow MR , Snyder PJ , Giacobini E , Khachaturian ZS |
Ref : J Prev Alzheimers Dis , 6 :2 , 2019 |
Abstract : |
PubMedSearch : Hampel_2019_J.Prev.Alzheimers.Dis_6_2 |
PubMedID: 30569080 |
Title : Sex and Gender Differences in the Brain Cholinergic System and in the Response to Therapy of Alzheimer Disease with Cholinesterase Inhibitors - Giacobini_2018_Curr.Alzheimer.Res_15_1077 |
Author(s) : Giacobini E , Pepeu G |
Ref : Curr Alzheimer Res , 15 :1077 , 2018 |
Abstract : |
PubMedSearch : Giacobini_2018_Curr.Alzheimer.Res_15_1077 |
PubMedID: 29895246 |
Title : The cholinergic system in the pathophysiology and treatment of Alzheimer's disease - Hampel_2018_Brain_141_1917 |
Author(s) : Hampel H , Mesulam MM , Cuello AC , Farlow MR , Giacobini E , Grossberg GT , Khachaturian AS , Vergallo A , Cavedo E , Snyder PJ , Khachaturian ZS |
Ref : Brain , 141 :1917 , 2018 |
Abstract : |
PubMedSearch : Hampel_2018_Brain_141_1917 |
PubMedID: 29850777 |
Title : Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014 - Schneider_2014_J.Intern.Med_275_251 |
Author(s) : Schneider LS , Mangialasche F , Andreasen N , Feldman H , Giacobini E , Jones R , Mantua V , Mecocci P , Pani L , Winblad B , Kivipelto M |
Ref : J Intern Med , 275 :251 , 2014 |
Abstract : |
PubMedSearch : Schneider_2014_J.Intern.Med_275_251 |
PubMedID: 24605808 |
Title : [New spectrum of HIV-associated cognitive disorders in the HAART era] - Du_2009_Rev.Med.Suisse_5_955 |
Author(s) : Du Pasquier R , Cavassini M , Simioni S , Annoni JM , Giacobini E , Hirschel B |
Ref : Rev Med Suisse , 5 :955 , 2009 |
Abstract : |
PubMedSearch : Du_2009_Rev.Med.Suisse_5_955 |
PubMedID: 19476058 |
Title : One hundred years after the discovery of Alzheimer's disease. A turning point for therapy? - Giacobini_2007_J.Alzheimers.Dis_12_37 |
Author(s) : Giacobini E , Becker RE |
Ref : J Alzheimers Dis , 12 :37 , 2007 |
Abstract : |
PubMedSearch : Giacobini_2007_J.Alzheimers.Dis_12_37 |
PubMedID: 17851193 |
Title : Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial - Onder_2005_Br.J.Psychiatry_187_450 |
Author(s) : Onder G , Zanetti O , Giacobini E , Frisoni GB , Bartorelli L , Carbone G , Lambertucci P , Silveri MC , Bernabei R |
Ref : British Journal of Psychiatry , 187 :450 , 2005 |
Abstract : |
PubMedSearch : Onder_2005_Br.J.Psychiatry_187_450 |
PubMedID: 16260821 |
Title : New indications for cholinesterase inhibitor therapy - |
Author(s) : Giacobini E |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :81 , 2004 |
PubMedID: |
Title : Cholinesterase inhibitors stabilize cognitive decline in Alzheimer patients through beta-amyloid metabolism interaction. - |
Author(s) : Giacobini E |
Ref : Cholinergic Mechanisms, CRC Press :411 , 2004 |
PubMedID: |
Title : Poster (38) Do cholinesterase inhibitors affect beta-amyloid metabolism in alzheimer patients? - |
Author(s) : Giacobini E |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :340 , 2004 |
PubMedID: |
Title : Cholinesterase inhibitors: new roles and therapeutic alternatives - Giacobini_2004_Pharmacol.Res_50_433 |
Author(s) : Giacobini E |
Ref : Pharmacol Res , 50 :433 , 2004 |
Abstract : |
PubMedSearch : Giacobini_2004_Pharmacol.Res_50_433 |
PubMedID: 15304240 |
Title : Cholinesterases: new roles in brain function and in Alzheimer's disease - Giacobini_2003_Neurochem.Res_28_515 |
Author(s) : Giacobini E |
Ref : Neurochem Res , 28 :515 , 2003 |
Abstract : |
PubMedSearch : Giacobini_2003_Neurochem.Res_28_515 |
PubMedID: 12675140 |
Title : A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease - Lahiri_2003_Curr.Drug.Targets_4_97 |
Author(s) : Lahiri DK , Farlow MR , Sambamurti K , Greig NH , Giacobini E , Schneider LS |
Ref : Curr Drug Targets , 4 :97 , 2003 |
Abstract : |
PubMedSearch : Lahiri_2003_Curr.Drug.Targets_4_97 |
PubMedID: 12558063 |
Title : Cholinergic function and Alzheimer's disease - Giacobini_2003_Int.J.Geriatr.Psychiatry_18_S1 |
Author(s) : Giacobini E |
Ref : Int J Geriatr Psychiatry , 18 :S1 , 2003 |
Abstract : |
PubMedSearch : Giacobini_2003_Int.J.Geriatr.Psychiatry_18_S1 |
PubMedID: 12973744 |
Title : Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit - Giacobini_2002_J.Neural.Transm.(Vienna)_109_1053 |
Author(s) : Giacobini E , Spiegel R , Enz A , Veroff AE , Cutler NR |
Ref : J Neural Transm (Vienna) , 109 :1053 , 2002 |
Abstract : |
PubMedSearch : Giacobini_2002_J.Neural.Transm.(Vienna)_109_1053 |
PubMedID: 12111443 |
Title : Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer' disease - Giacobini_2002_J.Neural.Transm.Suppl_62_181 |
Author(s) : Giacobini E |
Ref : J Neural Transm Suppl , 62 :181 , 2002 |
Abstract : |
PubMedSearch : Giacobini_2002_J.Neural.Transm.Suppl_62_181 |
PubMedID: 12456062 |
Title : Do cholinesterase inhibitors have disease-modifying effects in Alzheimer's disease? - Giacobini_2001_CNS.Drugs_15_85 |
Author(s) : Giacobini E |
Ref : CNS Drugs , 15 :85 , 2001 |
Abstract : |
PubMedSearch : Giacobini_2001_CNS.Drugs_15_85 |
PubMedID: 11460892 |
Title : Selective inhibitors of butyrylcholinesterase: a valid alternative for therapy of Alzheimer's disease? - Giacobini_2001_Drugs.Aging_18_891 |
Author(s) : Giacobini E |
Ref : Drugs & Aging , 18 :891 , 2001 |
Abstract : |
PubMedSearch : Giacobini_2001_Drugs.Aging_18_891 |
PubMedID: 11888344 |
Title : Is anti-cholinesterase therapy of Alzheimer's disease delaying progression? - Giacobini_2001_Aging.(Milano)_13_247 |
Author(s) : Giacobini E |
Ref : Aging (Milano) , 13 :247 , 2001 |
Abstract : |
PubMedSearch : Giacobini_2001_Aging.(Milano)_13_247 |
PubMedID: 11442306 |
Title : Cholinesterase inhibitors stabilize Alzheimer's disease - Giacobini_2000_Ann.N.Y.Acad.Sci_920_321 |
Author(s) : Giacobini E |
Ref : Annals of the New York Academy of Sciences , 920 :321 , 2000 |
Abstract : |
PubMedSearch : Giacobini_2000_Ann.N.Y.Acad.Sci_920_321 |
PubMedID: 11193171 |
Title : Cholinesterase inhibitors stabilize Alzheimer disease - Giacobini_2000_Neurochem.Res_25_1185 |
Author(s) : Giacobini E |
Ref : Neurochem Res , 25 :1185 , 2000 |
Abstract : |
PubMedSearch : Giacobini_2000_Neurochem.Res_25_1185 |
PubMedID: 11059792 |
Title : Present and future of Alzheimer therapy - Giacobini_2000_J.Neural.Transm.Suppl_59_231 |
Author(s) : Giacobini E |
Ref : J Neural Transm Suppl , 59 :231 , 2000 |
Abstract : |
PubMedSearch : Giacobini_2000_J.Neural.Transm.Suppl_59_231 |
PubMedID: 10961434 |
Title : Cholinesterase inhibitor therapy stabilizes symptoms of Alzheimer disease - Giacobini_2000_Alzheimer.Dis.Assoc.Disord_14 Suppl 1_S3 |
Author(s) : Giacobini E |
Ref : Alzheimer Disease & Associated Disorders , 14 Suppl 1 :S3 , 2000 |
Abstract : |
PubMedSearch : Giacobini_2000_Alzheimer.Dis.Assoc.Disord_14 Suppl 1_S3 |
PubMedID: 10850724 |
Title : Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein - Wevers_1999_Eur.J.Neurosci_11_2551 |
Author(s) : Wevers A , Monteggia L , Nowacki S , Bloch W , Schutz U , Lindstrom JM , Pereira EF , Eisenberg H , Giacobini E , de Vos RA , Steur EN , Maelicke A , Albuquerque EX , Schroder H |
Ref : European Journal of Neuroscience , 11 :2551 , 1999 |
Abstract : |
PubMedSearch : Wevers_1999_Eur.J.Neurosci_11_2551 |
PubMedID: 10383644 |
Title : Cholinergic foundations of Alzheimer's disease therapy - Giacobini_1998_J.Physiol.Paris_92_283 |
Author(s) : Giacobini E |
Ref : Journal de Physiologie (Paris) , 92 :283 , 1998 |
Abstract : |
PubMedSearch : Giacobini_1998_J.Physiol.Paris_92_283 |
PubMedID: 9789824 |
Title : Pharmacological Basis of Cholinergic Therapy in Alzheimer Disease - |
Author(s) : Giacobini E |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :153 , 1998 |
PubMedID: |
Title : Alzheimer's disease: Changes in the cerebrocortical expression of nicotinic receptors on the protein level - |
Author(s) : Wevers A , Nowacki S , Lindstrom JM , Schutz U , Giacobini E , Schroder H |
Ref : Journal de Physiologie (Paris) , 92 :509 , 1998 |
PubMedID: |
Title : Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: from tacrine to future applications - Giacobini_1998_Neurochem.Int_32_413 |
Author(s) : Giacobini E |
Ref : Neurochem Int , 32 :413 , 1998 |
Abstract : |
PubMedSearch : Giacobini_1998_Neurochem.Int_32_413 |
PubMedID: 9676739 |
Title : Treatment of Alzheimer's disease. New developments - Giacobini_1998_Ann.Med.Interne_149_231 |
Author(s) : Giacobini E , Michel JP |
Ref : Ann Med Interne , 149 :231 , 1998 |
Abstract : |
PubMedSearch : Giacobini_1998_Ann.Med.Interne_149_231 |
PubMedID: 11490551 |
Title : Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex - Summers_1997_Jpn.J.Pharmacol_74_139 |
Author(s) : Summers KL , Kem WR , Giacobini E |
Ref : Japanese Journal of Pharmacology , 74 :139 , 1997 |
Abstract : |
PubMedSearch : Summers_1997_Jpn.J.Pharmacol_74_139 |
PubMedID: 9243321 |
Title : From molecular structure to Alzheimer therapy - Giacobini_1997_Jpn.J.Pharmacol_74_225 |
Author(s) : Giacobini E |
Ref : Japanese Journal of Pharmacology , 74 :225 , 1997 |
Abstract : |
PubMedSearch : Giacobini_1997_Jpn.J.Pharmacol_74_225 |
PubMedID: 9268083 |
Title : Metrifonate. A viewpoint - |
Author(s) : Giacobini E |
Ref : Drugs & Aging , 11 :497 , 1997 |
PubMedID: 9413707 |
Title : Alzheimer disease, from molecular biology to therapy - Giacobini_1997_Adv.Exp.Med.Biol_429_235 |
Author(s) : Giacobini E |
Ref : Advances in Experimental Medicine & Biology , 429 :235 , 1997 |
Abstract : |
PubMedSearch : Giacobini_1997_Adv.Exp.Med.Biol_429_235 |
PubMedID: 9413578 |
Title : The effect of the selective reversible acetylcholinesterase inhibitor E2020 on extracellular acetylcholine and biogenic amine levels in rat cortex - Giacobini_1996_Neuropharmacol_35_205 |
Author(s) : Giacobini E , Zhu XD , Williams E , Sherman KA |
Ref : Neuropharmacology , 35 :205 , 1996 |
Abstract : |
PubMedSearch : Giacobini_1996_Neuropharmacol_35_205 |
PubMedID: 8734490 |
Title : The effect of cholinesterase inhibitors on the secretion of APPS from rat brain cortex - Giacobini_1996_Ann.N.Y.Acad.Sci_777_393 |
Author(s) : Giacobini E , Mori F , Lai CC |
Ref : Annals of the New York Academy of Sciences , 777 :393 , 1996 |
Abstract : |
PubMedSearch : Giacobini_1996_Ann.N.Y.Acad.Sci_777_393 |
PubMedID: 8624119 |
Title : New trends in cholinergic therapy for Alzheimer disease: nicotinic agonists or cholinesterase inhibitors? - |
Author(s) : Giacobini E |
Ref : Prog Brain Res , 109 :311 , 1996 |
PubMedID: 9009719 |
Title : Effect of MDL 73,745 on acetylcholine and biogenic amine levels in rat cortex - Zhu_1995_Eur.J.Pharmacol_276_93 |
Author(s) : Zhu XD , Giacobini E , Hornsperger JM |
Ref : European Journal of Pharmacology , 276 :93 , 1995 |
Abstract : |
PubMedSearch : Zhu_1995_Eur.J.Pharmacol_276_93 |
PubMedID: 7781701 |
Title : Cholinesterase Inhibitors - |
Author(s) : Giacobini E |
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :463 , 1995 |
PubMedID: |
Title : Second generation cholinesterase inhibitors: effect of (L)-huperzine-A on cortical biogenic amines - Zhu_1995_J.Neurosci.Res_41_828 |
Author(s) : Zhu XD , Giacobini E |
Ref : Journal of Neuroscience Research , 41 :828 , 1995 |
Abstract : |
PubMedSearch : Zhu_1995_J.Neurosci.Res_41_828 |
PubMedID: 7500384 |
Title : Therapy for Alzheimer's disease. Symptomatic or neuroprotective? - Giacobini_1994_Mol.Neurobiol_9_115 |
Author(s) : Giacobini E |
Ref : Molecular Neurobiology , 9 :115 , 1994 |
Abstract : |
PubMedSearch : Giacobini_1994_Mol.Neurobiol_9_115 |
PubMedID: 7888087 |
Title : Therapy of Alzheimer disease: symptomatic or neuroprotective? - Giacobini_1994_J.Neural.Transm.Suppl_43_211 |
Author(s) : Giacobini E |
Ref : J Neural Transm Suppl , 43 :211 , 1994 |
Abstract : |
PubMedSearch : Giacobini_1994_J.Neural.Transm.Suppl_43_211 |
PubMedID: 7884402 |
Title : Trimethylsilylated trifluoromethyl ketones, a novel class of acetylcholinesterase inhibitors: biochemical and pharmacological profile of MDL 73,745 - |
Author(s) : Hornsperger JM , Collard JN , Heydt JG , Giacobini E , Funes S , Dow J , Schirlin D |
Ref : Biochemical Society Transactions , 22 :758 , 1994 |
PubMedID: 7821680 |
Title : Cholinesterase inhibitor effects on neurotransmitters in rat cortex in vivo - Cuadra_1994_J.Pharmacol.Exp.Ther_270_277 |
Author(s) : Cuadra G , Summers K , Giacobini E |
Ref : Journal of Pharmacology & Experimental Therapeutics , 270 :277 , 1994 |
Abstract : |
PubMedSearch : Cuadra_1994_J.Pharmacol.Exp.Ther_270_277 |
PubMedID: 7913496 |
Title : Muscarinic receptors mediate attenuation of extracellular acetylcholine levels in rat cerebral cortex after cholinesterase inhibition - Messamore_1993_Neurosci.Lett_158_205 |
Author(s) : Messamore E , Warpman U , Williams E , Giacobini E |
Ref : Neuroscience Letters , 158 :205 , 1993 |
Abstract : |
PubMedSearch : Messamore_1993_Neurosci.Lett_158_205 |
PubMedID: 8233096 |
Title : Pharmacotherapy of Alzheimer disease: new drugs and novel strategies - |
Author(s) : Giacobini E |
Ref : Prog Brain Res , 98 :447 , 1993 |
PubMedID: 8248535 |
Title : Cholinesterase inhibitor effects on extracellular acetylcholine in rat cortex - Messamore_1993_Neuropharmacol_32_745 |
Author(s) : Messamore E , Warpman U , Ogane N , Giacobini E |
Ref : Neuropharmacology , 32 :745 , 1993 |
Abstract : |
PubMedSearch : Messamore_1993_Neuropharmacol_32_745 |
PubMedID: 8413838 |
Title : Preferential inhibition of acetylcholinesterase molecular forms in rat brain - Ogane_1992_Neurochem.Res_17_489 |
Author(s) : Ogane N , Giacobini E , Messamore E |
Ref : Neurochemical Research , 17 :489 , 1992 |
Abstract : |
PubMedSearch : Ogane_1992_Neurochem.Res_17_489 |
PubMedID: 1528356 |
Title : Differential inhibition of acetylcholinesterase molecular forms in normal and Alzheimer disease brain - Ogane_1992_Brain.Res_589_307 |
Author(s) : Ogane N , Giacobini E , Struble RG |
Ref : Brain Research , 589 :307 , 1992 |
Abstract : |
PubMedSearch : Ogane_1992_Brain.Res_589_307 |
PubMedID: 1393597 |
Title : Heptyl-physostigmine enhances basal forebrain control of cortical cerebral blood flow - Linville_1992_J.Neurosci.Res_31_573 |
Author(s) : Linville DG , Giacobini E , Arneric SP |
Ref : Journal of Neuroscience Research , 31 :573 , 1992 |
Abstract : |
PubMedSearch : Linville_1992_J.Neurosci.Res_31_573 |
PubMedID: 1640506 |
Title : New Cholinesterase Inhibitors for Treatment of Alzheimer Disease - |
Author(s) : Giacobini E |
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :322 , 1991 |
PubMedID: |
Title : Effects of L-beta-N-methylamino-L-alanine (L-BMAA) on the cortical cholinergic and glutamatergic systems of the rat - Rakonczay_1991_J.Neurosci.Res_29_121 |
Author(s) : Rakonczay Z , Matsuoka Y , Giacobini E |
Ref : Journal of Neuroscience Research , 29 :121 , 1991 |
Abstract : |
PubMedSearch : Rakonczay_1991_J.Neurosci.Res_29_121 |
PubMedID: 1653366 |
Title : Muscarinic cholinoceptive neurons in the frontal cortex in Alzheimer's disease - Schroder_1991_Brain.Res.Bull_27_631 |
Author(s) : Schroder H , Giacobini E , Struble RG , Luiten PG , van der Zee EA , Zilles K , Strosberg AD |
Ref : Brain Research Bulletin , 27 :631 , 1991 |
Abstract : |
PubMedSearch : Schroder_1991_Brain.Res.Bull_27_631 |
PubMedID: 1756381 |
Title : Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease - Schroder_1991_Neurobiol.Aging_12_259 |
Author(s) : Schroder H , Giacobini E , Struble RG , Zilles K , Maelicke A |
Ref : Neurobiology of Aging , 12 :259 , 1991 |
Abstract : |
PubMedSearch : Schroder_1991_Neurobiol.Aging_12_259 |
PubMedID: 1876232 |
Title : Cellular distribution and expression of cortical acetylcholine receptors in aging and Alzheimer's disease - Schroder_1991_Ann.N.Y.Acad.Sci_640_189 |
Author(s) : Schroder H , Giacobini E , Struble RG , Zilles K , Maelicke A , Luiten PG , Strosberg AD |
Ref : Annals of the New York Academy of Sciences , 640 :189 , 1991 |
Abstract : |
PubMedSearch : Schroder_1991_Ann.N.Y.Acad.Sci_640_189 |
PubMedID: 1776738 |
Title : Cerebrospinal fluid choline levels are decreased in Parkinson's disease [see comments] - Manyam_1990_Ann.Neurol_27_683 |
Author(s) : Manyam BV , Giacobini E , Colliver JA |
Ref : Annals of Neurology , 27 :683 , 1990 |
Abstract : |
PubMedSearch : Manyam_1990_Ann.Neurol_27_683 |
PubMedID: 2360805 |
Title : The cholinergic system in Alzheimer disease - |
Author(s) : Giacobini E |
Ref : Prog Brain Res , 84 :321 , 1990 |
PubMedID: 2267306 |
Title : Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease - Manyam_1990_Jf.Neurol_237_281 |
Author(s) : Manyam BV , Giacobini E , Colliver JA |
Ref : Journal of Neurology , 237 :281 , 1990 |
Abstract : |
PubMedSearch : Manyam_1990_Jf.Neurol_237_281 |
PubMedID: 2146369 |
Title : Cerebrospinal fluid as a reflector of central cholinergic and amino acid neurotransmitter activity in cerebellar ataxia - Manyam_1990_Arch.Neurol_47_1194 |
Author(s) : Manyam BV , Giacobini E , Ferraro TN , Hare TA |
Ref : Archives of Neurology , 47 :1194 , 1990 |
Abstract : |
PubMedSearch : Manyam_1990_Arch.Neurol_47_1194 |
PubMedID: 1978660 |
Title : Use of agraphia in subtyping of Alzheimer's disease - Kumar_1990_Arch.Gerontol.Geriatr_11_155 |
Author(s) : Kumar V , Giacobini E |
Ref : Arch Gerontol Geriatr , 11 :155 , 1990 |
Abstract : |
PubMedSearch : Kumar_1990_Arch.Gerontol.Geriatr_11_155 |
PubMedID: 15374487 |
Title : Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat - Tang_1989_J.Neurosci.Res_24_276 |
Author(s) : Tang XC , De Sarno P , Sugaya K , Giacobini E |
Ref : Journal of Neuroscience Research , 24 :276 , 1989 |
Abstract : |
PubMedSearch : Tang_1989_J.Neurosci.Res_24_276 |
PubMedID: 2585551 |
Title : CSF choline and acetylcholinesterase in early-onset vs. late-onset Alzheimer's disease patients - Kumar_1989_Acta.Neurol.Scand_80_461 |
Author(s) : Kumar V , Giacobini E , Markwell S |
Ref : Acta Neurologica Scandinavica , 80 :461 , 1989 |
Abstract : |
PubMedSearch : Kumar_1989_Acta.Neurol.Scand_80_461 |
PubMedID: 2589014 |
Title : The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat - De Sarno_1989_Neurochem.Res_14_971 |
Author(s) : De Sarno P , Pomponi M , Giacobini E , Tang XC , Williams E |
Ref : Neurochemical Research , 14 :971 , 1989 |
Abstract : |
PubMedSearch : De Sarno_1989_Neurochem.Res_14_971 |
PubMedID: 2608162 |
Title : Modulation of acetylcholine release by nicotinic receptors in the rat brain - De Sarno_1989_J.Neurosci.Res_22_194 |
Author(s) : De Sarno P , Giacobini E |
Ref : Journal of Neuroscience Research , 22 :194 , 1989 |
Abstract : |
PubMedSearch : De Sarno_1989_J.Neurosci.Res_22_194 |
PubMedID: 2709442 |
Title : Physostigmine, tacrine and metrifonate: the effect of multiple doses on acetylcholine metabolism in rat brain - Hallak_1989_Neuropharmacol_28_199 |
Author(s) : Hallak M , Giacobini E |
Ref : Neuropharmacology , 28 :199 , 1989 |
Abstract : |
PubMedSearch : Hallak_1989_Neuropharmacol_28_199 |
PubMedID: 2725846 |
Title : Choline levels are increased in cerebrospinal fluid of Alzheimer patients - Elble_1989_Neurobiol.Aging_10_45 |
Author(s) : Elble R , Giacobini E , Higgins C |
Ref : Neurobiology of Aging , 10 :45 , 1989 |
Abstract : |
PubMedSearch : Elble_1989_Neurobiol.Aging_10_45 |
PubMedID: 2755556 |
Title : Potential pharmacotherapy of Alzheimer disease. A comparison of various forms of physostigmine administration. - Becker_1988_Acta.Neurol.Scand.Supplementum_116_19 |
Author(s) : Becker R , Giacobini E , Elble R , McIlhany M , Sherman KA |
Ref : Acta Neurologica Scandinavica Supplementum , 116 :19 , 1988 |
Abstract : |
PubMedSearch : Becker_1988_Acta.Neurol.Scand.Supplementum_116_19 |
PubMedID: 3043998 |
Title : Cerebrospinal fluid choline, and acetylcholinesterase activity in familial vs. non-familial Alzheimer's disease patients - Kumar_1988_Arch.Geront.Geriat_7_111 |
Author(s) : Kumar V , Giacobini E |
Ref : Archives of Gerontology & Geriatrics , 7 :111 , 1988 |
Abstract : |
PubMedSearch : Kumar_1988_Arch.Geront.Geriat_7_111 |
PubMedID: 3415394 |
Title : The Cholinergic System in Aging - |
Author(s) : Giacobini E |
Ref : Handbook of Experimental Pharmacology , 86 :665 , 1988 |
PubMedID: |
Title : Cortisol responses to cholinergic drugs in Alzheimer's disease - Kumar_1988_Int.J.Clin.Pharmacol.Ther.Toxicol_26_471 |
Author(s) : Kumar V , Smith RC , Sherman KA , Ashford W , Murphy J , Giacobini E , Colliver J |
Ref : International Journal of Clinical Pharmacology, Therapy, & Toxicology , 26 :471 , 1988 |
Abstract : |
PubMedSearch : Kumar_1988_Int.J.Clin.Pharmacol.Ther.Toxicol_26_471 |
PubMedID: 3069749 |
Title : Cholinesterases in cerebrospinal fluid. A longitudinal study in Alzheimer disease - Elble_1987_Arch.Neurol_44_403 |
Author(s) : Elble R , Giacobini E , Scarsella G |
Ref : Archives of Neurology , 44 :403 , 1987 |
Abstract : |
PubMedSearch : Elble_1987_Arch.Neurol_44_403 |
PubMedID: 3827696 |
Title : Cerebrospinal fluid changes in experimental cardiac arrest (maximal stress) - Wortsman_1987_Am.J.Physiol_252_E756 |
Author(s) : Wortsman J , Foley PJ , Tacker WA , Giacobini E , Cryer PE , Frank S |
Ref : American Journal of Physiology , 252 :E756 , 1987 |
Abstract : |
PubMedSearch : Wortsman_1987_Am.J.Physiol_252_E756 |
PubMedID: 3591937 |
Title : Pharmacokinetics and pharmacodynamics of physostigmine after intravenous administration in beagle dogs - Giacobini_1987_Neuropharmacol_26_831 |
Author(s) : Giacobini E , Somani S , McIlhany M , Downen M , Hallak M |
Ref : Neuropharmacology , 26 :831 , 1987 |
Abstract : |
PubMedSearch : Giacobini_1987_Neuropharmacol_26_831 |
PubMedID: 3658115 |
Title : Release of acetylcholinesterase from the caudate nucleus of the rat - De Sarno_1987_J.Neurosci.Res_18_578 |
Author(s) : De Sarno P , Giacobini E , Downen M |
Ref : Journal of Neuroscience Research , 18 :578 , 1987 |
Abstract : |
PubMedSearch : De Sarno_1987_J.Neurosci.Res_18_578 |
PubMedID: 3437472 |
Title : Relation of brain regional physostigmine concentration to cholinesterase activity and acetylcholine and choline levels in rat - Hallak_1986_Neurochem.Res_11_1037 |
Author(s) : Hallak M , Giacobini E |
Ref : Neurochemical Research , 11 :1037 , 1986 |
Abstract : |
PubMedSearch : Hallak_1986_Neurochem.Res_11_1037 |
PubMedID: 3748273 |
Title : The effects of physostigmine on acetylcholinesterase activity of CSF plasma and brain. A comparison of intravenous and intraventricular administration in beagle dogs - Mattio_1986_Neuropharmacol_25_1167 |
Author(s) : Mattio T , McIlhany M , Giacobini E , Hallak M |
Ref : Neuropharmacology , 25 :1167 , 1986 |
Abstract : |
PubMedSearch : Mattio_1986_Neuropharmacol_25_1167 |
PubMedID: 3785584 |
Title : Aging of Cholinergic Synapses: Fiction or Reality? - |
Author(s) : Giacobini E , Mussini I , Mattio T |
Ref : Advances in Behavioral Biology , 30 :177 , 1986 |
PubMedID: |
Title : Effects of DFP on iridic metabolism and release of acetylcholine and on pupillary function in the rat - Mattio_1984_Neuropharmacol_23_1207 |
Author(s) : Mattio TG , Richardson JS , Giacobini E |
Ref : Neuropharmacology , 23 :1207 , 1984 |
Abstract : |
PubMedSearch : Mattio_1984_Neuropharmacol_23_1207 |
PubMedID: 6521855 |
Title : Development and aging of cholinergic synapses. V. Changes in nicotinic cholinergic receptor binding in ciliary ganglia and irises of the chicken - Marchi_1981_Dev.Neurosci_4_258 |
Author(s) : Marchi M , Yurkewicz L , Giacobini E , Fredrickson T |
Ref : Developmental Neuroscience , 4 :258 , 1981 |
Abstract : |
PubMedSearch : Marchi_1981_Dev.Neurosci_4_258 |
PubMedID: 7274093 |
Title : Acetylcholine Biosynthesis in Developing Cholinergic Synapses - |
Author(s) : Giacobini E , Marchi M |
Ref : Advances in Behavioral Biology , 25 :1 , 1981 |
PubMedID: |
Title : Aging of Cholinergic Synapses in the Peripheral Autonomic Nervous System - |
Author(s) : Marchi M , Giacobini E |
Ref : Advances in Behavioral Biology , 25 :25 , 1981 |
PubMedID: |
Title : Development and aging of cholinergic synapses. IV. Acetylcholinesterase and choline acetyltransferase activities in autonomic ganglia and iris of the chick - Marchi_1980_Dev.Neurosci_3_235 |
Author(s) : Marchi M , Hoffman DW , Giacobini E , Fredrickson T |
Ref : Developmental Neuroscience , 3 :235 , 1980 |
Abstract : |
PubMedSearch : Marchi_1980_Dev.Neurosci_3_235 |
PubMedID: 7460796 |
Title : Molecular forms of cholinesterases in cerebrospinal fluid, blood plasma, and brain tissue of the beagle dog - Scarsella_1979_J.Neurosci.Res_4_19 |
Author(s) : Scarsella G , Toschi G , Bareggi SR , Giacobini E |
Ref : Journal of Neuroscience Research , 4 :19 , 1979 |
Abstract : |
PubMedSearch : Scarsella_1979_J.Neurosci.Res_4_19 |
PubMedID: 423312 |
Title : Normal distribution and denervation changes of neurotransmitter related enzymes in cholinergic neurones - Giacobini_1979_J.Physiol_286_233 |
Author(s) : Giacobini E , Pilar G , Suszkiw JB , Uchimura H |
Ref : The Journal of Physiology , 286 :233 , 1979 |
Abstract : |
PubMedSearch : Giacobini_1979_J.Physiol_286_233 |
PubMedID: 220412 |
Title : Cholinergic receptors in synaptogenesis: drug-receptor interaction during development - |
Author(s) : Giacobini E |
Ref : Proceedings of the Western Pharmacology Society , 22 :15 , 1979 |
PubMedID: 515046 |
Title : Acetylcholinesterase activity in ventricular and cisternal CSF of dogs: effect of chlorpromazine - Bareggi_1978_J.Neurosci.Res_3_335 |
Author(s) : Bareggi SR , Giacobini E |
Ref : Journal of Neuroscience Research , 3 :335 , 1978 |
Abstract : |
PubMedSearch : Bareggi_1978_J.Neurosci.Res_3_335 |
PubMedID: 739556 |
Title : Time course of appearance of alpha-bungarotoxin binding sites during development of chick ciliary ganglion and iris - Chiappinelli_1978_Neurochem.Res_3_465 |
Author(s) : Chiappinelli VA , Giacobini E |
Ref : Neurochemical Research , 3 :465 , 1978 |
Abstract : |
PubMedSearch : Chiappinelli_1978_Neurochem.Res_3_465 |
PubMedID: 745659 |
Title : Molecular forms of acetylcholinesterase in the ciliary ganglion and iris of the chick. Developmental changes and effects of axotomy - Scarsella_1978_Dev.Neurosci_1_133 |
Author(s) : Scarsella G , Toschi G , Chiappinelli VA , Giacobini E |
Ref : Developmental Neuroscience , 1 :133 , 1978 |
Abstract : |
PubMedSearch : Scarsella_1978_Dev.Neurosci_1_133 |
PubMedID: 756378 |
Title : Developmental variations of tyrosine hydroxylase and acetylcholinesterase in embryonic and post-hatching chicken sympathetic ganglia - Fairman_1976_Brain.Res_102_301 |
Author(s) : Fairman K , Giacobini E , Chiappinelli V |
Ref : Brain Research , 102 :301 , 1976 |
Abstract : |
PubMedSearch : Fairman_1976_Brain.Res_102_301 |
PubMedID: 2367 |
Title : Induction of cholinergic enzymes in chick ciliary ganglion and iris muscle cells during synapse formation - Chiappinelli_1976_J.Physiol_257_749 |
Author(s) : Chiappinelli V , Giacobini E , Pilar G , Uchimura H |
Ref : The Journal of Physiology , 257 :749 , 1976 |
Abstract : |
PubMedSearch : Chiappinelli_1976_J.Physiol_257_749 |
PubMedID: 181563 |
Title : Activity of enzymes related to neurotransmission in neuronal and glial fractions - |
Author(s) : Hemminki K , Hemminki E , Giacobini E |
Ref : International Journal of Neuroscience , 5 :87 , 1973 |
PubMedID: 4349214 |
Title : Cholinergic transmission in the hypoglossal reinnervated nictitating membrane of the cat: an enzymatic, histochemical and physiological study - |
Author(s) : Koslow SH , Giacobini E , Kerpel-Fronius S , Olson L |
Ref : Journal of Pharmacology & Experimental Therapeutics , 180 :664 , 1972 |
PubMedID: 4335112 |
Title : Micro-scale procedure for the preparation of subcellular fractions from individual autonomic ganglia - |
Author(s) : Giacobini E , Hokfelt T , Kerpel-Fronius S , Koslow SH , Mitchard M , Nore B |
Ref : Journal of Neurochemistry , 18 :223 , 1971 |
PubMedID: 5550087 |
Title : Dopa-decarboxylase in autonomic and sensory ganglia of the cat - |
Author(s) : Giacobini E , Nore B |
Ref : Acta Physiologica Scandinavica , 82 :209 , 1971 |
PubMedID: 4326540 |
Title : Developmental changes of DOPA decarboxylase in chick embryo and chick spinal and sympathetic ganglia - |
Author(s) : Filogamo G , Giacobini E , Giacobini G , Nore B |
Ref : Journal of Neurochemistry , 18 :1589 , 1971 |
PubMedID: 4328513 |
Title : Biochemistry of synaptic plasticity studied in single neurons - |
Author(s) : Giacobini E |
Ref : Advances in Cytopharmacology , 1 :427 , 1971 |
PubMedID: 4356766 |
Title : Developmental changes of cholinesterases and monoamine oxidase in chick embryo spinal and sympathetic ganglia - |
Author(s) : Giacobini G , Marchisio PC , Giacobini E , Koslow SH |
Ref : Journal of Neurochemistry , 17 :1177 , 1970 |
PubMedID: 5457626 |
Title : A sensitive, automated magnetic diver balance - |
Author(s) : Mitchard M , Giacobini E , Carlsson B |
Ref : Analytical Biochemistry , 37 :112 , 1970 |
PubMedID: 5506542 |
Title : Biochemistry of synaptic plasticity studied in single neurons - |
Author(s) : Giacobini E |
Ref : Adv Biochem Psychopharmacol , 2 :9 , 1970 |
PubMedID: 4399550 |
Title : Comparative analysis of central and peripheral cholinergic synapses - |
Author(s) : Giacobini E |
Ref : Drugs and Cholinergic Mechanisms in the CNS :67 , 1970 |
PubMedID: |
Title : Value and limitations of quantitative chemical studies in individual cells. - |
Author(s) : Giacobini E |
Ref : Journal of Histochemistry & Cytochemistry , 17 :139 , 1969 |
PubMedID: 4891814 |
Title : An isotopic micromethod for the measurement of cholinesterase activity in individual cells - |
Author(s) : Koslow SH , Giacobini E |
Ref : Journal of Neurochemistry , 16 :1523 , 1969 |
PubMedID: 5380012 |
Title : Biochemistry and pharmacology of autonomic neurons - |
Author(s) : Giacobini E |
Ref : Annali dell Istituto Superiore di Sanita , 4 :459 , 1968 |
PubMedID: 4390004 |
Title : Monoamine oxidase in sympathetic ganglia of the cat - |
Author(s) : Consolo S , Giacobini E , Karjalainen K |
Ref : Acta Physiologica Scandinavica , 74 :513 , 1968 |
PubMedID: 4900044 |
Title : Cholinesterase activity in innervated and denervated sympathetic ganglion cells of the cat - |
Author(s) : Giacobini E , Palmborg B , Sjoqvist F |
Ref : Acta Physiologica Scandinavica , 69 :355 , 1967 |
PubMedID: 6033672 |
Title : Cholinacetylase in innervated and denervated sympathetic ganglia and ganglion cells of the cat - |
Author(s) : Buckley G , Consolo S , Giacobini E , Sjoqvist F |
Ref : Acta Physiologica Scandinavica , 71 :348 , 1967 |
PubMedID: 5587839 |
Title : Cholinergic and adrenergic cells in sympathetic ganglia - |
Author(s) : Giacobini E |
Ref : Annals of the New York Academy of Sciences , 144 :646 , 1967 |
PubMedID: |
Title : Quantitative determination of cholinesterase in individuel spinal ganglion cells - |
Author(s) : Giacobini E |
Ref : Acta Physiologica Scandinavica , 45 :238 , 1959 |
PubMedID: |
Title : Determination of cholinesterase in the cellular components of neurons - |
Author(s) : Giacobini E |
Ref : Acta Physiologica Scandinavica , 45 :311 , 1959 |
PubMedID: |
Title : The distribution and localisation of cholinesterases in nerve cells - |
Author(s) : Giacobini E |
Ref : Acta Physiologica Scandinavica , 156 :1 , 1959 |
PubMedID: |