| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Dual Cholinergic Modulation in Dementia: Quinuclidine Carbamates Targeting Butyrylcholinesterase and alpha7 Nicotinic Receptor - Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| Author(s) : Mastnak-Sokolov P , Knez D , Meden A , Strasek Benedik N , Ferjancic Benetik S , Hrast Rambaher M , Zorman M , Nachon F , Brazzolotto X , Jardemark K , Jungholm O , Bruton J , Strandback E , Nyman T , Shahid M , Gobec S |
| Ref : Chemico-Biological Interactions , :111830 , 2025 |
| Abstract : |
| PubMedSearch : Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| PubMedID: 41242410 |
| Gene_locus related to this paper: human-BCHE |
| Title : Dual Cholinergic Modulation in Dementia: Quinuclidine Carbamates Targeting Butyrylcholinesterase and alpha7 Nicotinic Receptor - Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| Author(s) : Mastnak-Sokolov P , Knez D , Meden A , Strasek Benedik N , Ferjancic Benetik S , Hrast Rambaher M , Zorman M , Nachon F , Brazzolotto X , Jardemark K , Jungholm O , Bruton J , Strandback E , Nyman T , Shahid M , Gobec S |
| Ref : Chemico-Biological Interactions , :111830 , 2025 |
| Abstract : |
| PubMedSearch : Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| PubMedID: 41242410 |
| Gene_locus related to this paper: human-BCHE |
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Dual Cholinergic Modulation in Dementia: Quinuclidine Carbamates Targeting Butyrylcholinesterase and alpha7 Nicotinic Receptor - Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| Author(s) : Mastnak-Sokolov P , Knez D , Meden A , Strasek Benedik N , Ferjancic Benetik S , Hrast Rambaher M , Zorman M , Nachon F , Brazzolotto X , Jardemark K , Jungholm O , Bruton J , Strandback E , Nyman T , Shahid M , Gobec S |
| Ref : Chemico-Biological Interactions , :111830 , 2025 |
| Abstract : |
| PubMedSearch : Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| PubMedID: 41242410 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2023_Eur.J.Med.Chem_247_115048 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2023 |
| Abstract : |
| PubMedSearch : Meden_2023_Eur.J.Med.Chem_247_115048 |
| PubMedID: 36586299 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2023_Eur.J.Med.Chem_247_115048 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2023 |
| Abstract : |
| PubMedSearch : Meden_2023_Eur.J.Med.Chem_247_115048 |
| PubMedID: 36586299 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2023_Eur.J.Med.Chem_247_115048 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2023 |
| Abstract : |
| PubMedSearch : Meden_2023_Eur.J.Med.Chem_247_115048 |
| PubMedID: 36586299 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__ |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S |
| Ref : Chemrxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__ |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S |
| Ref : Chemrxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__ |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S |
| Ref : Chemrxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |