| Title : Access to novel potent pleiotropic prodrugs, targeting both butyrylcholinesterase and serotonin reuptake, with anti-amnesic activities in Alzheimer's disease model - Travers-Lesage_2026_Eur.J.Med.Chem_307_118670 |
| Author(s) : Travers-Lesage V , Crouzier L , Antonijevic M , Wang A , Toublet FX , Davis A , Modeste F , Brazzolotto X , Nachon F , Since M , Maurice T , Rochais C , Dallemagne P |
| Ref : Eur Journal of Medicinal Chemistry , 307 :118670 , 2026 |
| Abstract : |
| PubMedSearch : Travers-Lesage_2026_Eur.J.Med.Chem_307_118670 |
| PubMedID: 41702369 |
| Title : Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer's Disease - Travers-Lesage_2026_ACS.Chem.Neurosci__ |
| Author(s) : Travers-Lesage V , Since M , Wang A , Davis A , Fayolle D , Bernay B , Modeste F , Nachon F , Brazzalotto X , Crouzier L , Sopkova-de Oliveira Santos J , Maurice T , Dallemagne P , Rochais C |
| Ref : ACS Chem Neurosci , : , 2026 |
| Abstract : |
| PubMedSearch : Travers-Lesage_2026_ACS.Chem.Neurosci__ |
| PubMedID: 41972598 |
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2023_Eur.J.Med.Chem_247_115048 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2023 |
| Abstract : |
| PubMedSearch : Meden_2023_Eur.J.Med.Chem_247_115048 |
| PubMedID: 36586299 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__ |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S |
| Ref : Chemrxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |