| Title : Daraxonrasib (RMC-6236) pharmacokinetics: impact of transporters and drug-metabolizing enzymes on a first-in-class pan-RAS molecular glue - Schinkel_2026_Pharmacol.Res__108226 |
| Author(s) : Schinkel A , Arguedas D , Bui V , Law T , Rijmers J , Tissier R , Beijnen JH , van Tellingen O , Lebre MC |
| Ref : Pharmacol Res , :108226 , 2026 |
| Abstract : |
| PubMedSearch : Schinkel_2026_Pharmacol.Res__108226 |
| PubMedID: 42107507 |
| Title : OATP1A\/1B Transporters Affect Irinotecan and SN-38 Pharmacokinetics and Carboxylesterase Expression in Knockout and Humanized Transgenic Mice - Iusuf_2014_Mol.Cancer.Ther_13_492 |
| Author(s) : Iusuf D , Ludwig M , Elbatsh A , van Esch A , van de Steeg E , Wagenaar E , van der Valk M , Lin F , van Tellingen O , Schinkel AH |
| Ref : Mol Cancer Ther , 13 :492 , 2014 |
| Abstract : |
| PubMedSearch : Iusuf_2014_Mol.Cancer.Ther_13_492 |
| PubMedID: 24194565 |