Beijnen JH

References (9)

Title : ABCB1 attenuates brain exposure to the KRAS(G12C) inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure - Rijmers_2024_Biomed.Pharmacother_175_116720
Author(s) : Rijmers J , Retmana IA , Bui V , Arguedas D , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH
Ref : Biomed Pharmacother , 175 :116720 , 2024
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PubMedSearch : Rijmers_2024_Biomed.Pharmacother_175_116720
PubMedID: 38733773

Title : Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice - Loos_2024_Mol.Pharm__
Author(s) : Loos NHC , Ferreira Martins ML , Rijmers J , de Jong D , Lebre MC , Tibben M , Beijnen JH , Schinkel AH
Ref : Mol Pharm , : , 2024
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PubMedSearch : Loos_2024_Mol.Pharm__
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Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618
Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH
Ref : Acta Pharm Sin B , 13 :618 , 2023
Abstract :
PubMedSearch : Gan_2023_Acta.Pharm.Sin.B_13_618
PubMedID: 36873183
Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h

Title : Pharmacokinetics of the KRAS(G12C) inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c - Loos_2023_Biomed.Pharmacother_166_115304
Author(s) : Loos NHC , Retmana IA , Rijmers J , Wang Y , Gan C , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH
Ref : Biomed Pharmacother , 166 :115304 , 2023
Abstract :
PubMedSearch : Loos_2023_Biomed.Pharmacother_166_115304
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Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956
Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH
Ref : Biomed Pharmacother , 164 :114956 , 2023
Abstract :
PubMedSearch : Gan_2023_Biomed.Pharmacother_164_114956
PubMedID: 37267638
Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e

Title : Individualized evaluation of cholinesterase inhibitors effects in dementia with adaptive cognitive testing - Wouters_2016_Int.J.Methods.Psychiatr.Res_25_190
Author(s) : Wouters H , Van Campen JP , Appels BA , Beijnen JH , Zwinderman AH , van Gool WA , Schmand B
Ref : Int J Methods Psychiatr Res , 25 :190 , 2016
Abstract :
PubMedSearch : Wouters_2016_Int.J.Methods.Psychiatr.Res_25_190
PubMedID: 26299847

Title : P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice - Tang_2015_Mol.Pharm_12_3714
Author(s) : Tang SC , Kort A , Cheung KL , Rosing H , Fukami T , Durmus S , Wagenaar E , Hendrikx JJ , Nakajima M , van Vlijmen BJ , Beijnen JH , Schinkel AH
Ref : Mol Pharm , 12 :3714 , 2015
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PubMedSearch : Tang_2015_Mol.Pharm_12_3714
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Title : P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice - Tang_2014_Clin.Cancer.Res_20_3133
Author(s) : Tang SC , Sparidans RW , Cheung KL , Fukami T , Durmus S , Wagenaar E , Yokoi T , van Vlijmen BJ , Beijnen JH , Schinkel AH
Ref : Clin Cancer Research , 20 :3133 , 2014
Abstract :
PubMedSearch : Tang_2014_Clin.Cancer.Res_20_3133
PubMedID: 24727322

Title : P-glycoprotein, multidrug-resistance associated protein 2, cyp3a, and carboxylesterase affect the oral availability and metabolism of vinorelbine - Lagas_2012_Mol.Pharmacol_82_636
Author(s) : Lagas JS , Damen CW , van Waterschoot RA , Iusuf D , Beijnen JH , Schinkel AH
Ref : Molecular Pharmacology , 82 :636 , 2012
Abstract :
PubMedSearch : Lagas_2012_Mol.Pharmacol_82_636
PubMedID: 22767610