| Title : Intestinal human carboxylesterase 2 (CES2) expression rescues drug metabolism and most metabolic syndrome phenotypes in global Ces2 cluster knockout mice - Wang_2024_Acta.Pharmacol.Sin__ |
| Author(s) : Wang YG , Gan CP , Beukers-Korver J , Rosing H , Li WL , Wagenaar E , Lebre MC , Song JY , Pritchard C , Bin Ali R , Huijbers I , Beijnen JH , Schinkel AH |
| Ref : Acta Pharmacol Sin , : , 2024 |
| Abstract : |
| PubMedSearch : Wang_2024_Acta.Pharmacol.Sin__ |
| PubMedID: 39496863 |
| Gene_locus related to this paper: human-CES2 , mouse-Ces2a , mouse-Ces2b , mouse-Ces2c , mouse-Ces2d-ps , mouse-Ces2e , mouse-Ces2f , mouse-Ces2g , mouse-Ces2h |
| Title : Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c - Rijmers_2024_Mol.Pharm__ |
| Author(s) : Rijmers J , Sparidans RW , Acda M , Loos NHC , Epeslidou E , Bui V , Lebre MC , Tibben M , Beijnen JH , Schinkel AH |
| Ref : Mol Pharm , : , 2024 |
| Abstract : |
| PubMedSearch : Rijmers_2024_Mol.Pharm__ |
| PubMedID: 39312722 |
| Title : ABCB1 attenuates brain exposure to the KRAS(G12C) inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure - Rijmers_2024_Biomed.Pharmacother_175_116720 |
| Author(s) : Rijmers J , Retmana IA , Bui V , Arguedas D , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 175 :116720 , 2024 |
| Abstract : |
| PubMedSearch : Rijmers_2024_Biomed.Pharmacother_175_116720 |
| PubMedID: 38733773 |
| Title : Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice - Loos_2024_Mol.Pharm__ |
| Author(s) : Loos NHC , Ferreira Martins ML , Rijmers J , de Jong D , Lebre MC , Tibben M , Beijnen JH , Schinkel AH |
| Ref : Mol Pharm , : , 2024 |
| Abstract : |
| PubMedSearch : Loos_2024_Mol.Pharm__ |
| PubMedID: 38423793 |
| Title : Pharmacokinetics of the KRAS(G12C) inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c - Loos_2023_Biomed.Pharmacother_166_115304 |
| Author(s) : Loos NHC , Retmana IA , Rijmers J , Wang Y , Gan C , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 166 :115304 , 2023 |
| Abstract : |
| PubMedSearch : Loos_2023_Biomed.Pharmacother_166_115304 |
| PubMedID: 37586117 |
| Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618 |
| Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH |
| Ref : Acta Pharm Sin B , 13 :618 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Acta.Pharm.Sin.B_13_618 |
| PubMedID: 36873183 |
| Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h |
| Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956 |
| Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 164 :114956 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Biomed.Pharmacother_164_114956 |
| PubMedID: 37267638 |
| Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e |
| Title : Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice - van Maanen_2009_Arthritis.Rheum_60_114 |
| Author(s) : van Maanen MA , Lebre MC , van der Poll T , Larosa GJ , Elbaum D , Vervoordeldonk MJ , Tak PP |
| Ref : Arthritis Rheum , 60 :114 , 2009 |
| Abstract : |
| PubMedSearch : van Maanen_2009_Arthritis.Rheum_60_114 |
| PubMedID: 19116908 |