| Title : Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c - Rijmers_2024_Mol.Pharm__ |
| Author(s) : Rijmers J , Sparidans RW , Acda M , Loos NHC , Epeslidou E , Bui V , Lebre MC , Tibben M , Beijnen JH , Schinkel AH |
| Ref : Mol Pharm , : , 2024 |
| Abstract : |
| PubMedSearch : Rijmers_2024_Mol.Pharm__ |
| PubMedID: 39312722 |
| Title : ABCB1 attenuates brain exposure to the KRAS(G12C) inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure - Rijmers_2024_Biomed.Pharmacother_175_116720 |
| Author(s) : Rijmers J , Retmana IA , Bui V , Arguedas D , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 175 :116720 , 2024 |
| Abstract : |
| PubMedSearch : Rijmers_2024_Biomed.Pharmacother_175_116720 |
| PubMedID: 38733773 |