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| Title : Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain - Perez-Medrano_2009_J.Med.Chem_52_3366 |
| Author(s) : Perez-Medrano A , Donnelly-Roberts D , Honore P , Hsieh GC , Namovic MT , Peddi S , Shuai Q , Wang Y , Faltynek CR , Jarvis MF , Carroll WA |
| Ref : Journal of Medicinal Chemistry , 52 :3366 , 2009 |
| Abstract : Perez-Medrano_2009_J.Med.Chem_52_3366 |
| ESTHER : Perez-Medrano_2009_J.Med.Chem_52_3366 |
| PubMedSearch : Perez-Medrano_2009_J.Med.Chem_52_3366 |
| PubMedID: 19397270 |
| Title : 1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction - Kolasa_2006_J.Med.Chem_49_5093 |
| Author(s) : Kolasa T , Matulenko MA , Hakeem AA , Patel MV , Mortell K , Bhatia P , Henry R , Nakane M , Hsieh GC , Terranova MA , Uchic ME , Miller LN , Chang R , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Martino B , El Kouhen O , Marsh KC , Wetter JM , Moreland RB , Brioni JD , Stewart AO |
| Ref : Journal of Medicinal Chemistry , 49 :5093 , 2006 |
| Abstract : Kolasa_2006_J.Med.Chem_49_5093 |
| ESTHER : Kolasa_2006_J.Med.Chem_49_5093 |
| PubMedSearch : Kolasa_2006_J.Med.Chem_49_5093 |
| PubMedID: 16913699 |
| Title : Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzam ide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction - Patel_2006_J.Med.Chem_49_7450 |
| Author(s) : Patel MV , Kolasa T , Mortell K , Matulenko MA , Hakeem AA , Rohde JJ , Nelson SL , Cowart MD , Nakane M , Miller LN , Uchic ME , Terranova MA , El-Kouhen OF , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Chang R , Martino BR , Wetter JM , Marsh KC , Martin R , Darbyshire JF , Gintant G , Hsieh GC , Moreland RB , Sullivan JP , Brioni JD , Stewart AO |
| Ref : Journal of Medicinal Chemistry , 49 :7450 , 2006 |
| Abstract : Patel_2006_J.Med.Chem_49_7450 |
| ESTHER : Patel_2006_J.Med.Chem_49_7450 |
| PubMedSearch : Patel_2006_J.Med.Chem_49_7450 |
| PubMedID: 17149874 |
| Title : 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist - Nakane_2005_Neuropharmacol_49_112 |
| Author(s) : Nakane M , Cowart MD , Hsieh GC , Miller L , Uchic ME , Chang R , Terranova MA , Donnelly-Roberts D , Namovic MT , Miller TR , Wetter JM , Marsh K , Stewart AO , Brioni JD , Moreland RB |
| Ref : Neuropharmacology , 49 :112 , 2005 |
| Abstract : Nakane_2005_Neuropharmacol_49_112 |
| ESTHER : Nakane_2005_Neuropharmacol_49_112 |
| PubMedSearch : Nakane_2005_Neuropharmacol_49_112 |
| PubMedID: 15992586 |
| Title : Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine - Hsieh_2004_J.Pharmacol.Exp.Ther_308_330 |
| Author(s) : Hsieh GC , Hollingsworth PR , Martino B , Chang R , Terranova MA , O'Neill AB , Lynch JJ , Moreland RB , Donnelly-Roberts D , Kolasa T , Mikusa JP , McVey JM , Marsh KC , Sullivan JP , Brioni JD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 308 :330 , 2004 |
| Abstract : Hsieh_2004_J.Pharmacol.Exp.Ther_308_330 |
| ESTHER : Hsieh_2004_J.Pharmacol.Exp.Ther_308_330 |
| PubMedSearch : Hsieh_2004_J.Pharmacol.Exp.Ther_308_330 |
| PubMedID: 14569075 |
| Title : Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats - Brioni_2004_Proc.Natl.Acad.Sci.U.S.A_101_6758 |
| Author(s) : Brioni JD , Moreland RB , Cowart M , Hsieh GC , Stewart AO , Hedlund P , Donnelly-Roberts D , Nakane M , Lynch JJ, 3rd , Kolasa T , Polakowski JS , Osinski MA , Marsh K , Andersson KE , Sullivan JP |
| Ref : Proc Natl Acad Sci U S A , 101 :6758 , 2004 |
| Abstract : Brioni_2004_Proc.Natl.Acad.Sci.U.S.A_101_6758 |
| ESTHER : Brioni_2004_Proc.Natl.Acad.Sci.U.S.A_101_6758 |
| PubMedSearch : Brioni_2004_Proc.Natl.Acad.Sci.U.S.A_101_6758 |
| PubMedID: 15087502 |
| Title : Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction - Cowart_2004_J.Med.Chem_47_3853 |
| Author(s) : Cowart M , Latshaw SP , Bhatia P , Daanen JF , Rohde J , Nelson SL , Patel M , Kolasa T , Nakane M , Uchic ME , Miller LN , Terranova MA , Chang R , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Martino BR , Lynch JJ, 3rd , Sullivan JP , Hsieh GC , Moreland RB , Brioni JD , Stewart AO |
| Ref : Journal of Medicinal Chemistry , 47 :3853 , 2004 |
| Abstract : Cowart_2004_J.Med.Chem_47_3853 |
| ESTHER : Cowart_2004_J.Med.Chem_47_3853 |
| PubMedSearch : Cowart_2004_J.Med.Chem_47_3853 |
| PubMedID: 15239663 |