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| Title : Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice - Damaj_2007_J.Pharmacol.Exp.Ther_321_1161 |
| Author(s) : Damaj MI , Fonck C , Marks MJ , Deshpande P , Labarca C , Lester HA , Collins AC , Martin BR |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 321 :1161 , 2007 |
| Abstract : Damaj_2007_J.Pharmacol.Exp.Ther_321_1161 |
| ESTHER : Damaj_2007_J.Pharmacol.Exp.Ther_321_1161 |
| PubMedSearch : Damaj_2007_J.Pharmacol.Exp.Ther_321_1161 |
| PubMedID: 17371806 |
| Title : Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path - Nashmi_2007_J.Neurosci_27_8202 |
| Author(s) : Nashmi R , Xiao C , Deshpande P , McKinney S , Grady SR , Whiteaker P , Huang Q , McClure-Begley TD , Lindstrom JM , Labarca C , Collins AC , Marks MJ , Lester HA |
| Ref : Journal of Neuroscience , 27 :8202 , 2007 |
| Abstract : Nashmi_2007_J.Neurosci_27_8202 |
| ESTHER : Nashmi_2007_J.Neurosci_27_8202 |
| PubMedSearch : Nashmi_2007_J.Neurosci_27_8202 |
| PubMedID: 17670967 |
| Title : Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation - Teper_2007_J.Neurosci_27_10128 |
| Author(s) : Teper Y , Whyte D , Cahir E , Lester HA , Grady SR , Marks MJ , Cohen BN , Fonck C , McClure-Begley TD , McIntosh JM , Labarca C , Lawrence A , Chen F , Gantois I , Davies PJ , Petrou S , Murphy M , Waddington J , Horne MK , Berkovic SF , Drago J |
| Ref : Journal of Neuroscience , 27 :10128 , 2007 |
| Abstract : Teper_2007_J.Neurosci_27_10128 |
| ESTHER : Teper_2007_J.Neurosci_27_10128 |
| PubMedSearch : Teper_2007_J.Neurosci_27_10128 |
| PubMedID: 17881519 |
| Title : Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons - Schwarz_2006_FASEB.J_20_935 |
| Author(s) : Schwarz J , Schwarz SC , Dorigo O , Stutzer A , Wegner F , Labarca C , Deshpande P , Gil JS , Berk AJ , Lester HA |
| Ref : FASEB Journal , 20 :935 , 2006 |
| Abstract : Schwarz_2006_FASEB.J_20_935 |
| ESTHER : Schwarz_2006_FASEB.J_20_935 |
| PubMedSearch : Schwarz_2006_FASEB.J_20_935 |
| PubMedID: 16675851 |
| Title : Novel seizure phenotype and sleep disruptions in knock-in mice with hypersensitive alpha 4* nicotinic receptors - Fonck_2005_J.Neurosci_25_11396 |
| Author(s) : Fonck C , Cohen BN , Nashmi R , Whiteaker P , Wagenaar DA , Rodrigues-Pinguet N , Deshpande P , McKinney S , Kwoh S , Munoz J , Labarca C , Collins AC , Marks MJ , Lester HA |
| Ref : Journal of Neuroscience , 25 :11396 , 2005 |
| Abstract : Fonck_2005_J.Neurosci_25_11396 |
| ESTHER : Fonck_2005_J.Neurosci_25_11396 |
| PubMedSearch : Fonck_2005_J.Neurosci_25_11396 |
| PubMedID: 16339034 |
| Title : Knockin mice with Leu9'Ser alpha4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally - Orb_2004_Physiol.Genomics_18_299 |
| Author(s) : Orb S , Wieacker J , Labarca C , Fonck C , Lester HA , Schwarz J |
| Ref : Physiol Genomics , 18 :299 , 2004 |
| Abstract : Orb_2004_Physiol.Genomics_18_299 |
| ESTHER : Orb_2004_Physiol.Genomics_18_299 |
| PubMedSearch : Orb_2004_Physiol.Genomics_18_299 |
| PubMedID: 15199190 |
| Title : Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization - Tapper_2004_Science_306_1029 |
| Author(s) : Tapper AR , McKinney SL , Nashmi R , Schwarz J , Deshpande P , Labarca C , Whiteaker P , Marks MJ , Collins AC , Lester HA |
| Ref : Science , 306 :1029 , 2004 |
| Abstract : Tapper_2004_Science_306_1029 |
| ESTHER : Tapper_2004_Science_306_1029 |
| PubMedSearch : Tapper_2004_Science_306_1029 |
| PubMedID: 15528443 |
| Title : Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action - Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633 |
| Author(s) : Lester HA , Fonck C , Tapper AR , McKinney S , Damaj MI , Balogh S , Owens J , Wehner JM , Collins AC , Labarca C |
| Ref : Curr Opin Drug Discov Devel , 6 :633 , 2003 |
| Abstract : Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633 |
| ESTHER : Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633 |
| PubMedSearch : Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633 |
| PubMedID: 14579512 |
| Title : Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons - Nashmi_2003_J.Neurosci_23_11554 |
| Author(s) : Nashmi R , Dickinson ME , McKinney S , Jareb M , Labarca C , Fraser SE , Lester HA |
| Ref : Journal of Neuroscience , 23 :11554 , 2003 |
| Abstract : Nashmi_2003_J.Neurosci_23_11554 |
| ESTHER : Nashmi_2003_J.Neurosci_23_11554 |
| PubMedSearch : Nashmi_2003_J.Neurosci_23_11554 |
| PubMedID: 14684858 |
| Title : Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response - Owens_2003_Alcohol.Clin.Exp.Res_27_1867 |
| Author(s) : Owens JC , Balogh SA , McClure-Begley TD , Butt CM , Labarca C , Lester HA , Picciotto MR , Wehner JM , Collins AC |
| Ref : Alcohol Clin Exp Res , 27 :1867 , 2003 |
| Abstract : Owens_2003_Alcohol.Clin.Exp.Res_27_1867 |
| ESTHER : Owens_2003_Alcohol.Clin.Exp.Res_27_1867 |
| PubMedSearch : Owens_2003_Alcohol.Clin.Exp.Res_27_1867 |
| PubMedID: 14691373 |
| Title : Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors - Fonck_2003_J.Neurosci_23_2582 |
| Author(s) : Fonck C , Nashmi R , Deshpande P , Damaj MI , Marks MJ , Riedel A , Schwarz J , Collins AC , Labarca C , Lester HA |
| Ref : Journal of Neuroscience , 23 :2582 , 2003 |
| Abstract : Fonck_2003_J.Neurosci_23_2582 |
| ESTHER : Fonck_2003_J.Neurosci_23_2582 |
| PubMedSearch : Fonck_2003_J.Neurosci_23_2582 |
| PubMedID: 12684443 |
| Title : Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety - Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786 |
| Author(s) : Labarca C , Schwarz J , Deshpande P , Schwarz S , Nowak MW , Fonck C , Nashmi R , Kofuji P , Dang H , Shi W , Fidan M , Khakh BS , Chen Z , Bowers BJ , Boulter J , Wehner JM , Lester HA |
| Ref : Proc Natl Acad Sci U S A , 98 :2786 , 2001 |
| Abstract : Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786 |
| ESTHER : Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786 |
| PubMedSearch : Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786 |
| PubMedID: 11226318 |
| Title : Voltage-jump relaxation kinetics for wild-type and chimeric beta subunits of neuronal nicotinic receptors - Figl_1996_J.Gen.Physiol_107_369 |
| Author(s) : Figl A , Labarca C , Davidson N , Lester HA , Cohen BN |
| Ref : Journal of General Physiology , 107 :369 , 1996 |
| Abstract : Figl_1996_J.Gen.Physiol_107_369 |
| ESTHER : Figl_1996_J.Gen.Physiol_107_369 |
| PubMedSearch : Figl_1996_J.Gen.Physiol_107_369 |
| PubMedID: 8868048 |
| Title : Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors - Labarca_1995_Nature_376_514 |
| Author(s) : Labarca C , Nowak MW , Zhang H , Tang L , Deshpande P , Lester HA |
| Ref : Nature , 376 :514 , 1995 |
| Abstract : Labarca_1995_Nature_376_514 |
| ESTHER : Labarca_1995_Nature_376_514 |
| PubMedSearch : Labarca_1995_Nature_376_514 |
| PubMedID: 7637783 |
| Title : Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors - Cohen_1995_J.Gen.Physiol_105_745 |
| Author(s) : Cohen BN , Figl A , Quick MW , Labarca C , Davidson N , Lester HA |
| Ref : Journal of General Physiology , 105 :745 , 1995 |
| Abstract : Cohen_1995_J.Gen.Physiol_105_745 |
| ESTHER : Cohen_1995_J.Gen.Physiol_105_745 |
| PubMedSearch : Cohen_1995_J.Gen.Physiol_105_745 |
| PubMedID: 7561742 |
| Title : Pharmacological and kinetic properties of alpha 4 beta 2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes - Charnet_1992_J.Physiol_450_375 |
| Author(s) : Charnet P , Labarca C , Cohen BN , Davidson N , Lester HA , Pilar G |
| Ref : The Journal of Physiology , 450 :375 , 1992 |
| Abstract : Charnet_1992_J.Physiol_450_375 |
| ESTHER : Charnet_1992_J.Physiol_450_375 |
| PubMedSearch : Charnet_1992_J.Physiol_450_375 |
| PubMedID: 1359123 |
| Title : Structure of the gamma-less nicotinic acetylcholine receptor: learning from omission - Charnet_1992_Mol.Pharmacol_41_708 |
| Author(s) : Charnet P , Labarca C , Lester HA |
| Ref : Molecular Pharmacology , 41 :708 , 1992 |
| Abstract : Charnet_1992_Mol.Pharmacol_41_708 |
| ESTHER : Charnet_1992_Mol.Pharmacol_41_708 |
| PubMedSearch : Charnet_1992_Mol.Pharmacol_41_708 |
| PubMedID: 1373800 |
| Title : Tris+\/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region - Cohen_1992_J.Gen.Physiol_99_545 |
| Author(s) : Cohen BN , Labarca C , Czyzyk L , Davidson N , Lester HA |
| Ref : Journal of General Physiology , 99 :545 , 1992 |
| Abstract : Cohen_1992_J.Gen.Physiol_99_545 |
| ESTHER : Cohen_1992_J.Gen.Physiol_99_545 |
| PubMedSearch : Cohen_1992_J.Gen.Physiol_99_545 |
| PubMedID: 1597678 |
| Title : Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations - Cohen_1992_J.Gen.Physiol_100_373 |
| Author(s) : Cohen BN , Labarca C , Davidson N , Lester HA |
| Ref : Journal of General Physiology , 100 :373 , 1992 |
| Abstract : Cohen_1992_J.Gen.Physiol_100_373 |
| ESTHER : Cohen_1992_J.Gen.Physiol_100_373 |
| PubMedSearch : Cohen_1992_J.Gen.Physiol_100_373 |
| PubMedID: 1431803 |
| Title : Mutations affecting local anesthetic block of the nicotinic acetylcholine receptor ion channel - |
| Author(s) : Leonard RJ , Charnet P , Labarca C , Vogelaar NJ , Czyzyk L , Gouin A , Davidson N , Lester HA |
| Ref : NIDA Res Monogr , 111 :28 , 1991 |
| PubMedID: 1723151 |
| Title : Reverse pharmacology of the nicotinic acetylcholine receptor. Mapping the local anesthetic binding site - Leonard_1991_Ann.N.Y.Acad.Sci_625_588 |
| Author(s) : Leonard RJ , Charnet P , Labarca C , Vogelaar NJ , Czyzyk L , Gouin A , Davidson N , Lester HA |
| Ref : Annals of the New York Academy of Sciences , 625 :588 , 1991 |
| Abstract : Leonard_1991_Ann.N.Y.Acad.Sci_625_588 |
| ESTHER : Leonard_1991_Ann.N.Y.Acad.Sci_625_588 |
| PubMedSearch : Leonard_1991_Ann.N.Y.Acad.Sci_625_588 |
| PubMedID: 2058913 |
| Title : Low molecular weight mRNA encodes a protein that controls serotonin 5-HT1c and acetylcholine M1 receptor sensitivity in Xenopus oocytes - Walter_1991_J.Gen.Physiol_98_399 |
| Author(s) : Walter AE , Hoger JH , Labarca C , Yu L , Davidson N , Lester HA |
| Ref : Journal of General Physiology , 98 :399 , 1991 |
| Abstract : Walter_1991_J.Gen.Physiol_98_399 |
| ESTHER : Walter_1991_J.Gen.Physiol_98_399 |
| PubMedSearch : Walter_1991_J.Gen.Physiol_98_399 |
| PubMedID: 1940855 |
| Title : Expression of ion channels and receptors in Xenopus oocytes using vaccinia virus - Yang_1991_FASEB.J_5_2209 |
| Author(s) : Yang XC , Karschin A , Labarca C , Elroy-Stein O , Moss B , Davidson N , Lester HA |
| Ref : FASEB Journal , 5 :2209 , 1991 |
| Abstract : Yang_1991_FASEB.J_5_2209 |
| ESTHER : Yang_1991_FASEB.J_5_2209 |
| PubMedSearch : Yang_1991_FASEB.J_5_2209 |
| PubMedID: 1708738 |
| Title : Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart - Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694 |
| Author(s) : Karschin A , Ho BY , Labarca C , Elroy-Stein O , Moss B , Davidson N , Lester HA |
| Ref : Proc Natl Acad Sci U S A , 88 :5694 , 1991 |
| Abstract : Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694 |
| ESTHER : Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694 |
| PubMedSearch : Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694 |
| PubMedID: 1905814 |
| Title : An open-channel blocker interacts with adjacent turns of alpha-helices in the nicotinic acetylcholine receptor - Charnet_1990_Neuron_4_87 |
| Author(s) : Charnet P , Labarca C , Leonard RJ , Vogelaar NJ , Czyzyk L , Gouin A , Davidson N , Lester HA |
| Ref : Neuron , 4 :87 , 1990 |
| Abstract : Charnet_1990_Neuron_4_87 |
| ESTHER : Charnet_1990_Neuron_4_87 |
| PubMedSearch : Charnet_1990_Neuron_4_87 |
| PubMedID: 1690017 |