Damaj MI

General

Full name : Damaj M Imad

First name : M Imad

Mail : Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Box 980613, Richmond, VA 23298-0613

Zip Code :

City :

Country : USA

Email : m.damaj@vcuhealth.org

Phone :

Fax :

Website :

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Comment

References (130)

Title : Differential roles of diacylglycerol lipase (DAGL) enzymes in nicotine withdrawal - Buzzi_2023_Brain.Res_1817_148483
Author(s) : Buzzi B , Koseli E , Alkhlaif Y , Parker A , Mustafa MA , Lichtman AH , Buczynski MW , Damaj MI
Ref : Brain Research , 1817 :148483 , 2023
Abstract :
PubMedSearch : Buzzi_2023_Brain.Res_1817_148483
PubMedID: 37442250

Title : Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice - Muldoon_2020_Neuropharmacol__108170
Author(s) : Muldoon PP , Akinola LS , Schlosburg JE , Lichtman AH , Sim-Selley LJ , Mahadevan A , Cravatt BF , Damaj MI
Ref : Neuropharmacology , :108170 , 2020
Abstract :
PubMedSearch : Muldoon_2020_Neuropharmacol__108170
PubMedID: 32479813
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy - Curry_2018_J.Pharmacol.Exp.Ther_366_169
Author(s) : Curry ZA , Wilkerson JL , Bagdas D , Kyte SL , Patel N , Donvito G , Mustafa MA , Poklis JL , Niphakis MJ , Hsu KL , Cravatt BF , Gewirtz DA , Damaj MI , Lichtman AH
Ref : Journal of Pharmacology & Experimental Therapeutics , 366 :169 , 2018
Abstract :
PubMedSearch : Curry_2018_J.Pharmacol.Exp.Ther_366_169
PubMedID: 29540562

Title : Basic Science and Public Policy: Informed Regulation for Nicotine and Tobacco Products - Fowler_2018_Nicotine.Tob.Res_20_789
Author(s) : Fowler CD , Gipson CD , Kleykamp BA , Rupprecht LE , Harrell PT , Rees VW , Gould TJ , Oliver J , Bagdas D , Damaj MI , Schmidt HD , Duncan A , De Biasi M
Ref : Nicotine Tob Res , 20 :789 , 2018
Abstract :
PubMedSearch : Fowler_2018_Nicotine.Tob.Res_20_789
PubMedID: 29065200

Title : Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice - Owens_2017_Neuropharmacol_125_80
Author(s) : Owens RA , Mustafa MA , Ignatowska-Jankowska BM , Damaj MI , Beardsley PM , Wiley JL , Niphakis MJ , Cravatt BF , Lichtman AH
Ref : Neuropharmacology , 125 :80 , 2017
Abstract :
PubMedSearch : Owens_2017_Neuropharmacol_125_80
PubMedID: 28673548

Title : Diacylglycerol lipase beta inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain - Wilkerson_2016_Br.J.Pharmacol_173_1678
Author(s) : Wilkerson JL , Ghosh S , Bagdas D , Mason BL , Crowe MS , Hsu KL , Wise LE , Kinsey SG , Damaj MI , Cravatt BF , Lichtman AH
Ref : British Journal of Pharmacology , 173 :1678 , 2016
Abstract :
PubMedSearch : Wilkerson_2016_Br.J.Pharmacol_173_1678
PubMedID: 26915789

Title : The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain - Bagdas_2015_Biochem.Pharmacol_97(4)_590
Author(s) : Bagdas D , AlSharari SD , Freitas K , Tracy M , Damaj MI
Ref : Biochemical Pharmacology , 97 :590 , 2015
Abstract :
PubMedSearch : Bagdas_2015_Biochem.Pharmacol_97(4)_590
PubMedID: 25931144

Title : Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice - Gamage_2015_Drug.Alcohol.Depend_146_7
Author(s) : Gamage TF , Ignatowska-Jankowska BM , Muldoon PP , Cravatt BF , Damaj MI , Lichtman AH
Ref : Drug Alcohol Depend , 146 :7 , 2015
Abstract :
PubMedSearch : Gamage_2015_Drug.Alcohol.Depend_146_7
PubMedID: 25479915

Title : Inhibition of monoacylglycerol lipase reduces nicotine withdrawal - Muldoon_2015_Br.J.Pharmacol_172_869
Author(s) : Muldoon PP , Chen J , Harenza JL , Abdullah RA , Sim-Selley LJ , Cravatt BF , Miles MF , Chen X , Lichtman AH , Damaj MI
Ref : British Journal of Pharmacology , 172 :869 , 2015
Abstract :
PubMedSearch : Muldoon_2015_Br.J.Pharmacol_172_869
PubMedID: 25258021
Gene_locus related to this paper: human-MGLL

Title : The nicotinic alpha6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2\/3 receptors - Wieskopf_2015_Sci.Transl.Med_7_287ra72
Author(s) : Wieskopf JS , Mathur J , Limapichat W , Post MR , Al-Qazzaz M , Sorge RE , Martin LJ , Zaykin DV , Smith SB , Freitas K , Austin JS , Dai F , Zhang J , Marcovitz J , Tuttle AH , Slepian PM , Clarke S , Drenan RM , Janes J , Al Sharari S , Segall SK , Aasvang EK , Lai W , Bittner R , Richards CI , Slade GD , Kehlet H , Walker J , Maskos U , Changeux JP , Devor M , Maixner W , Diatchenko L , Belfer I , Dougherty DA , Su AI , Lummis SC , Damaj MI , Lester HA , Patapoutian A , Mogil JS
Ref : Sci Transl Med , 7 :287ra72 , 2015
Abstract :
PubMedSearch : Wieskopf_2015_Sci.Transl.Med_7_287ra72
PubMedID: 25972004

Title : Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice - Harenza_2014_Genes.Brain.Behav_13_213
Author(s) : Harenza JL , Muldoon PP , De Biasi M , Damaj MI , Miles MF
Ref : Genes Brain Behav , 13 :213 , 2014
Abstract :
PubMedSearch : Harenza_2014_Genes.Brain.Behav_13_213
PubMedID: 24289814

Title : The alpha4 nicotinic receptor promotes CD4+ T-cell proliferation and a helper T-cell immune response - Nordman_2014_Mol.Pharmacol_85_50
Author(s) : Nordman JC , Muldoon P , Clark S , Damaj MI , Kabbani N
Ref : Molecular Pharmacology , 85 :50 , 2014
Abstract :
PubMedSearch : Nordman_2014_Mol.Pharmacol_85_50
PubMedID: 24107512

Title : Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5\/6 Inhibitor - Alsharari_2014_Nicotine.Tob.Res_16_18
Author(s) : AlSharari SD , Siu EC , Tyndale RF , Damaj MI
Ref : Nicotine Tob Res , 16 :18 , 2014
Abstract :
PubMedSearch : Alsharari_2014_Nicotine.Tob.Res_16_18
PubMedID: 23884323

Title : Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2'-Fluoro-3'-(substituted pyridinyl)-7-deschloroepibatidine Analogues - Ondachi_2014_J.Med.Chem_57_836
Author(s) : Ondachi PW , Castro AH , Bartkowiak JM , Luetje CW , Damaj MI , Mascarella SW , Navarro HA , Carroll FI
Ref : Journal of Medicinal Chemistry , 57 :836 , 2014
Abstract :
PubMedSearch : Ondachi_2014_J.Med.Chem_57_836
PubMedID: 24428686

Title : The beta2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse - Dawson_2013_Alcohol_47_85
Author(s) : Dawson A , Miles MF , Damaj MI
Ref : Alcohol , 47 :85 , 2013
Abstract :
PubMedSearch : Dawson_2013_Alcohol_47_85
PubMedID: 23419392

Title : Early smoking onset and risk for subsequent nicotine dependence: a monozygotic co-twin control study - Kendler_2013_Am.J.Psychiatry_170_408
Author(s) : Kendler KS , Myers J , Damaj MI , Chen X
Ref : Am J Psychiatry , 170 :408 , 2013
Abstract :
PubMedSearch : Kendler_2013_Am.J.Psychiatry_170_408
PubMedID: 23318372

Title : The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence - Muldoon_2013_Life.Sci_92_458
Author(s) : Muldoon PP , Lichtman AH , Parsons LH , Damaj MI
Ref : Life Sciences , 92 :458 , 2013
Abstract :
PubMedSearch : Muldoon_2013_Life.Sci_92_458
PubMedID: 22705310

Title : Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal and nicotine-induced reinstatement of preference in mice - Alajaji_2013_Psychopharmacology.(Berl)_228_419
Author(s) : Alajaji M , Bowers MS , Knackstedt L , Damaj MI
Ref : Psychopharmacology (Berl) , 228 :419 , 2013
Abstract :
PubMedSearch : Alajaji_2013_Psychopharmacology.(Berl)_228_419
PubMedID: 23503685

Title : The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice - Ignatowska-Jankowska_2013_Psychopharmacology.(Berl)_229_591
Author(s) : Ignatowska-Jankowska BM , Muldoon PP , Lichtman AH , Damaj MI
Ref : Psychopharmacology (Berl) , 229 :591 , 2013
Abstract :
PubMedSearch : Ignatowska-Jankowska_2013_Psychopharmacology.(Berl)_229_591
PubMedID: 23652588

Title : Novel insights on the effect of nicotine in a murine colitis model - AlSharari_2013_J.Pharmacol.Exp.Ther_344_207
Author(s) : AlSharari SD , Akbarali HI , Abdullah RA , Shahab O , Auttachoat W , Ferreira GA , White KL , Lichtman AH , Cabral GA , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 344 :207 , 2013
Abstract :
PubMedSearch : AlSharari_2013_J.Pharmacol.Exp.Ther_344_207
PubMedID: 23115221

Title : Calcium\/calmodulin-dependent protein kinase IV mediates acute nicotine-induced antinociception in acute thermal pain tests - Jackson_2013_Behav.Pharmacol_24_689
Author(s) : Jackson KJ , Damaj MI
Ref : Behav Pharmacol , 24 :689 , 2013
Abstract :
PubMedSearch : Jackson_2013_Behav.Pharmacol_24_689
PubMedID: 24196027

Title : Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice - Jackson_2013_Psychopharmacology.(Berl)_226_763
Author(s) : Jackson KJ , McLaughlin JP , Carroll FI , Damaj MI
Ref : Psychopharmacology (Berl) , 226 :763 , 2013
Abstract :
PubMedSearch : Jackson_2013_Psychopharmacology.(Berl)_226_763
PubMedID: 22526543

Title : The antinociceptive effects of nicotinic receptors alpha7-positive allosteric modulators in murine acute and tonic pain models - Freitas_2013_J.Pharmacol.Exp.Ther_344_264
Author(s) : Freitas K , Carroll FI , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 344 :264 , 2013
Abstract :
PubMedSearch : Freitas_2013_J.Pharmacol.Exp.Ther_344_264
PubMedID: 23115222

Title : In vivo pharmacological interactions between a type II positive allosteric modulator of alpha7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model - Freitas_2013_Br.J.Pharmacol_169_567
Author(s) : Freitas K , Negus SS , Carroll FI , Damaj MI
Ref : British Journal of Pharmacology , 169 :567 , 2013
Abstract :
PubMedSearch : Freitas_2013_Br.J.Pharmacol_169_567
PubMedID: 23004024

Title : The alpha3beta4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the alpha5 subunit in the mouse - Jackson_2013_Neuropharmacol_70_228
Author(s) : Jackson KJ , Sanjakdar SS , Muldoon PP , McIntosh JM , Damaj MI
Ref : Neuropharmacology , 70 :228 , 2013
Abstract :
PubMedSearch : Jackson_2013_Neuropharmacol_70_228
PubMedID: 23416040

Title : The histidine triad nucleotide binding 1 protein is involved in nicotine reward and physical nicotine withdrawal in mice - Jackson_2013_Neurosci.Lett_550_129
Author(s) : Jackson KJ , Wang JB , Barbier E , Damaj MI , Chen X
Ref : Neuroscience Letters , 550 :129 , 2013
Abstract :
PubMedSearch : Jackson_2013_Neurosci.Lett_550_129
PubMedID: 23810802

Title : Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice - Alsharari_2013_Biochem.Pharmacol_86(8)_1201
Author(s) : AlSharari SD , Freitas K , Damaj MI
Ref : Biochemical Pharmacology , 86 :1201 , 2013
Abstract :
PubMedSearch : Alsharari_2013_Biochem.Pharmacol_86(8)_1201
PubMedID: 23811428

Title : Effects of the specific alpha4beta2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice - Tobey_2012_Psychopharmacology.(Berl)_223_159
Author(s) : Tobey KM , Walentiny DM , Wiley JL , Carroll FI , Damaj MI , Azar MR , Koob GF , George O , Harris LS , Vann RE
Ref : Psychopharmacology (Berl) , 223 :159 , 2012
Abstract :
PubMedSearch : Tobey_2012_Psychopharmacology.(Berl)_223_159
PubMedID: 22526534

Title : Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine - Ondachi_2012_J.Med.Chem_55_6512
Author(s) : Ondachi P , Castro A , Luetje CW , Damaj MI , Mascarella SW , Navarro HA , Carroll FI
Ref : Journal of Medicinal Chemistry , 55 :6512 , 2012
Abstract :
PubMedSearch : Ondachi_2012_J.Med.Chem_55_6512
PubMedID: 22742586

Title : Acute behavioral effects of nicotine in male and female HINT1 knockout mice - Jackson_2012_Genes.Brain.Behav_11_993
Author(s) : Jackson KJ , Wang JB , Barbier E , Chen X , Damaj MI
Ref : Genes Brain Behav , 11 :993 , 2012
Abstract :
PubMedSearch : Jackson_2012_Genes.Brain.Behav_11_993
PubMedID: 22827509

Title : The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models - AlSharari_2012_J.Pharmacol.Exp.Ther_342_742
Author(s) : AlSharari SD , Carroll FI , McIntosh JM , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 342 :742 , 2012
Abstract :
PubMedSearch : AlSharari_2012_J.Pharmacol.Exp.Ther_342_742
PubMedID: 22678099

Title : Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium\/calmodulin-dependent protein kinase IV knockout mice - Jackson_2012_PLoS.One_7_e51154
Author(s) : Jackson KJ , Sanjakdar SS , Chen X , Damaj MI
Ref : PLoS ONE , 7 :e51154 , 2012
Abstract :
PubMedSearch : Jackson_2012_PLoS.One_7_e51154
PubMedID: 23226481

Title : Function of human alpha3beta4alpha5 nicotinic acetylcholine receptors is reduced by the alpha5(D398N) variant - George_2012_J.Biol.Chem_287_25151
Author(s) : George AA , Lucero LM , Damaj MI , Lukas RJ , Chen X , Whiteaker P
Ref : Journal of Biological Chemistry , 287 :25151 , 2012
Abstract :
PubMedSearch : George_2012_J.Biol.Chem_287_25151
PubMedID: 22665477

Title : Bupropion and its main metabolite reverse nicotine chronic tolerance in the mouse - Grabus_2012_Nicotine.Tob.Res_14_1356
Author(s) : Grabus SD , Carroll FI , Damaj MI
Ref : Nicotine Tob Res , 14 :1356 , 2012
Abstract :
PubMedSearch : Grabus_2012_Nicotine.Tob.Res_14_1356
PubMedID: 22589419

Title : ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure - Chen_2011_PLoS.One_6_e28790
Author(s) : Chen J , Brunzell DH , Jackson K , van der Vaart A , Ma JZ , Payne TJ , Sherva R , Farrer LA , Gejman P , Levinson DF , Holmans P , Aggen SH , Damaj MI , Kuo PH , Webb BT , Anton R , Kranzler HR , Gelernter J , Li MD , Kendler KS , Chen X
Ref : PLoS ONE , 6 :e28790 , 2011
Abstract :
PubMedSearch : Chen_2011_PLoS.One_6_e28790
PubMedID: 22205969

Title : Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine - Carroll_2011_J.Med.Chem_54_1441
Author(s) : Carroll FI , Muresan AZ , Blough BE , Navarro HA , Mascarella SW , Eaton JB , Huang X , Damaj MI , Lukas RJ
Ref : Journal of Medicinal Chemistry , 54 :1441 , 2011
Abstract :
PubMedSearch : Carroll_2011_J.Med.Chem_54_1441
PubMedID: 21319801

Title : The neuropeptide galanin and variants in the GalR1 gene are associated with nicotine dependence - Jackson_2011_Neuropsychopharmacology_36_2339
Author(s) : Jackson KJ , Chen X , Miles MF , Harenza J , Damaj MI
Ref : Neuropsychopharmacology , 36 :2339 , 2011
Abstract :
PubMedSearch : Jackson_2011_Neuropsychopharmacology_36_2339
PubMedID: 21796100

Title : Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration - George_2011_Psychopharmacology.(Berl)_213_715
Author(s) : George O , Lloyd A , Carroll FI , Damaj MI , Koob GF
Ref : Psychopharmacology (Berl) , 213 :715 , 2011
Abstract :
PubMedSearch : George_2011_Psychopharmacology.(Berl)_213_715
PubMedID: 20924754

Title : Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice - Kota_2011_Biochem.Pharmacol_82(8)_1008
Author(s) : Kota D , Sanjakdar S , Marks MJ , Khabour O , Alzoubi K , Damaj MI
Ref : Biochemical Pharmacology , 82 :1008 , 2011
Abstract :
PubMedSearch : Kota_2011_Biochem.Pharmacol_82(8)_1008
PubMedID: 21708139

Title : Poster: Functional examination of human alpha4\/beta2alpha5 nicotinic AChRs transfected in SH-EP1 cells -
Author(s) : Abdrakhmanova GR , Simard AR , Whiteaker P , Lukas RJ , Damaj MI , Kendler K , Chen X
Ref : Biochemical Pharmacology , 82 :1023 , 2011
PubMedID:

Title : {alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis - Abdrakhmanova_2010_Am.J.Physiol.Gastrointest.Liver.Physiol_299_G761
Author(s) : Abdrakhmanova GR , AlSharari S , Kang M , Damaj MI , Akbarali HI
Ref : American Journal of Physiology Gastrointest Liver Physiol , 299 :G761 , 2010
Abstract :
PubMedSearch : Abdrakhmanova_2010_Am.J.Physiol.Gastrointest.Liver.Physiol_299_G761
PubMedID: 20595621

Title : In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs - Abdrakhmanova_2010_Neuropharmacol_59_511
Author(s) : Abdrakhmanova GR , Blough BE , Nesloney C , Navarro HA , Damaj MI , Carroll FI
Ref : Neuropharmacology , 59 :511 , 2010
Abstract :
PubMedSearch : Abdrakhmanova_2010_Neuropharmacol_59_511
PubMedID: 20633568

Title : Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2beta-substituted tropanes - Carroll_2010_J.Med.Chem_53_8345
Author(s) : Carroll FI , Blough BE , Mascarella SW , Navarro HA , Eaton JB , Lukas RJ , Damaj MI
Ref : Journal of Medicinal Chemistry , 53 :8345 , 2010
Abstract :
PubMedSearch : Carroll_2010_J.Med.Chem_53_8345
PubMedID: 21058665

Title : Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation - Carroll_2010_J.Med.Chem_53_2204
Author(s) : Carroll FI , Blough BE , Mascarella SW , Navarro HA , Eaton JB , Lukas RJ , Damaj MI
Ref : Journal of Medicinal Chemistry , 53 :2204 , 2010
Abstract :
PubMedSearch : Carroll_2010_J.Med.Chem_53_2204
PubMedID: 20158204

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists - Carroll_2010_J.Nat.Prod_73_306
Author(s) : Carroll FI , Ma W , Deng L , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Natural Products , 73 :306 , 2010
Abstract :
PubMedSearch : Carroll_2010_J.Nat.Prod_73_306
PubMedID: 20038125

Title : Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse - Jackson_2010_Psychopharmacology.(Berl)_210_285
Author(s) : Jackson KJ , Carroll FI , Negus SS , Damaj MI
Ref : Psychopharmacology (Berl) , 210 :285 , 2010
Abstract :
PubMedSearch : Jackson_2010_Psychopharmacology.(Berl)_210_285
PubMedID: 20232057

Title : Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice - Jackson_2010_J.Pharmacol.Exp.Ther_334_137
Author(s) : Jackson KJ , Marks MJ , Vann RE , Chen X , Gamage TF , Warner JA , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :137 , 2010
Abstract :
PubMedSearch : Jackson_2010_J.Pharmacol.Exp.Ther_334_137
PubMedID: 20400469

Title : Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation - Lukas_2010_J.Med.Chem_53_4731
Author(s) : Lukas RJ , Muresan AZ , Damaj MI , Blough BE , Huang X , Navarro HA , Mascarella SW , Eaton JB , Marxer-Miller SK , Carroll FI
Ref : Journal of Medicinal Chemistry , 53 :4731 , 2010
Abstract :
PubMedSearch : Lukas_2010_J.Med.Chem_53_4731
PubMedID: 20509659

Title : Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor - Zhang_2010_J.Med.Chem_53_7048
Author(s) : Zhang Y , Gilliam A , Maitra R , Damaj MI , Tajuba JM , Seltzman HH , Thomas BF
Ref : Journal of Medicinal Chemistry , 53 :7048 , 2010
Abstract :
PubMedSearch : Zhang_2010_J.Med.Chem_53_7048
PubMedID: 20845959

Title : Effects of hydroxymetabolites of bupropion on nicotine dependence behavior in mice - Damaj_2010_J.Pharmacol.Exp.Ther_334_1087
Author(s) : Damaj MI , Grabus SD , Navarro HA , Vann RE , Warner JA , King LS , Wiley JL , Blough BE , Lukas RJ , Carroll FI
Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :1087 , 2010
Abstract :
PubMedSearch : Damaj_2010_J.Pharmacol.Exp.Ther_334_1087
PubMedID: 20576796

Title : Poster: Nicotine suppresses hyperexcitability of inflamed colonic sensory neurons -
Author(s) : Abdrakhmanova GR , Akbarali HI , Sharari SA , Damaj MI
Ref : Biochemical Pharmacology , 78 :924 , 2009
PubMedID:

Title : L-type calcium channels and calcium\/calmodulin-dependent kinase II differentially mediate behaviors associated with nicotine withdrawal in mice - Jackson_2009_J.Pharmacol.Exp.Ther_330_152
Author(s) : Jackson KJ , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :152 , 2009
Abstract :
PubMedSearch : Jackson_2009_J.Pharmacol.Exp.Ther_330_152
PubMedID: 19336664

Title : The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion - Jackson_2009_Neuropharmacol_56_970
Author(s) : Jackson KJ , Kota DH , Martin BR , Damaj MI
Ref : Neuropharmacology , 56 :970 , 2009
Abstract :
PubMedSearch : Jackson_2009_Neuropharmacol_56_970
PubMedID: 19371584

Title : Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium\/calmodulin-dependent protein kinase II-dependent pathways in vivo - Jackson_2009_J.Pharmacol.Exp.Ther_330_541
Author(s) : Jackson KJ , Walters CL , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :541 , 2009
Abstract :
PubMedSearch : Jackson_2009_J.Pharmacol.Exp.Ther_330_541
PubMedID: 19435931

Title : Characterization of pharmacological and behavioral differences to nicotine in C57Bl\/6 and DBA\/2 mice - Jackson_2009_Neuropharmacol_57_347
Author(s) : Jackson KJ , Walters CL , Miles MF , Martin BR , Damaj MI
Ref : Neuropharmacology , 57 :347 , 2009
Abstract :
PubMedSearch : Jackson_2009_Neuropharmacol_57_347
PubMedID: 19619563

Title : The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal - Jackson_2009_J.Pharmacol.Exp.Ther_331_547
Author(s) : Jackson KJ , McIntosh JM , Brunzell DH , Sanjakdar SS , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 331 :547 , 2009
Abstract :
PubMedSearch : Jackson_2009_J.Pharmacol.Exp.Ther_331_547
PubMedID: 19644040

Title : Enhanced nicotine reward in adulthood after exposure to nicotine during early adolescence in mice - Kota_2009_Biochem.Pharmacol_78(7)_873
Author(s) : Kota D , Robinson SE , Damaj MI
Ref : Biochemical Pharmacology , 78 :873 , 2009
Abstract :
PubMedSearch : Kota_2009_Biochem.Pharmacol_78(7)_873
PubMedID: 19576867

Title : Age-dependent differences in nicotine reward and withdrawal in female mice - Kota_2008_Psychopharmacology.(Berl)_198_201
Author(s) : Kota D , Martin BR , Damaj MI
Ref : Psychopharmacology (Berl) , 198 :201 , 2008
Abstract :
PubMedSearch : Kota_2008_Psychopharmacology.(Berl)_198_201
PubMedID: 18338157

Title : The endogenous cannabinoid system modulates nicotine reward and dependence - Merritt_2008_J.Pharmacol.Exp.Ther_326_483
Author(s) : Merritt LL , Martin BR , Walters C , Lichtman AH , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 326 :483 , 2008
Abstract :
PubMedSearch : Merritt_2008_J.Pharmacol.Exp.Ther_326_483
PubMedID: 18451315

Title : 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs - Abdrakhmanova_2008_Neuropharmacol_55_1287
Author(s) : Abdrakhmanova GR , Carroll FI , Damaj MI , Martin BR
Ref : Neuropharmacology , 55 :1287 , 2008
Abstract :
PubMedSearch : Abdrakhmanova_2008_Neuropharmacol_55_1287
PubMedID: 18775444

Title : Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs - Ivy_2008_Bioorg.Med.Chem_16_746
Author(s) : Ivy Carroll F , Yokota Y , Ma W , Lee JR , Brieaddy LE , Burgess JP , Navarro HA , Damaj MI , Martin BR
Ref : Bioorganic & Medicinal Chemistry , 16 :746 , 2008
Abstract :
PubMedSearch : Ivy_2008_Bioorg.Med.Chem_16_746
PubMedID: 17964169

Title : Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs - Jackson_2008_J.Pharmacol.Exp.Ther_325_302
Author(s) : Jackson KJ , Martin BR , Changeux JP , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 325 :302 , 2008
Abstract :
PubMedSearch : Jackson_2008_J.Pharmacol.Exp.Ther_325_302
PubMedID: 18184829

Title : Guidelines on nicotine dose selection for in vivo research - Matta_2007_Psychopharmacology.(Berl)_190_269
Author(s) : Matta SG , Balfour DJ , Benowitz NL , Boyd RT , Buccafusco JJ , Caggiula AR , Craig CR , Collins AC , Damaj MI , Donny EC , Gardiner PS , Grady SR , Heberlein U , Leonard SS , Levin ED , Lukas RJ , Markou A , Marks MJ , McCallum SE , Parameswaran N , Perkins KA , Picciotto MR , Quik M , Rose JE , Rothenfluh A , Schafer WR , Stolerman IP , Tyndale RF , Wehner JM , Zirger JM
Ref : Psychopharmacology (Berl) , 190 :269 , 2007
Abstract :
PubMedSearch : Matta_2007_Psychopharmacology.(Berl)_190_269
PubMedID: 16896961

Title : Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice - Damaj_2007_J.Pharmacol.Exp.Ther_321_1161
Author(s) : Damaj MI , Fonck C , Marks MJ , Deshpande P , Labarca C , Lester HA , Collins AC , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 321 :1161 , 2007
Abstract :
PubMedSearch : Damaj_2007_J.Pharmacol.Exp.Ther_321_1161
PubMedID: 17371806

Title : Nicotine dependence and reward differ between adolescent and adult male mice - Kota_2007_J.Pharmacol.Exp.Ther_322_399
Author(s) : Kota D , Martin BR , Robinson SE , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 322 :399 , 2007
Abstract :
PubMedSearch : Kota_2007_J.Pharmacol.Exp.Ther_322_399
PubMedID: 17446302

Title : Behavioral modulation of neuronal calcium\/calmodulin-dependent protein kinase II activity: differential effects on nicotine-induced spinal and supraspinal antinociception in mice - Damaj_2007_Biochem.Pharmacol_74(8)_1247
Author(s) : Damaj MI
Ref : Biochemical Pharmacology , 74 :1247 , 2007
Abstract :
PubMedSearch : Damaj_2007_Biochem.Pharmacol_74(8)_1247
PubMedID: 17850767

Title : Alpha-7 nicotinic acetylcholine receptor agonists selectively activate limbic regions of the rat forebrain: an effect similar to antipsychotics - Hansen_2007_J.Neurosci.Res_85_1810
Author(s) : Hansen HH , Timmermann DB , Peters D , Walters C , Damaj MI , Mikkelsen JD
Ref : Journal of Neuroscience Research , 85 :1810 , 2007
Abstract :
PubMedSearch : Hansen_2007_J.Neurosci.Res_85_1810
PubMedID: 17455307

Title : Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine - Carroll_2007_J.Med.Chem_50_6383
Author(s) : Carroll FI , Robinson TP , Brieaddy LE , Atkinson RN , Mascarella SW , Damaj MI , Martin BR , Navarro HA
Ref : Journal of Medicinal Chemistry , 50 :6383 , 2007
Abstract :
PubMedSearch : Carroll_2007_J.Med.Chem_50_6383
PubMedID: 17994682

Title : Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs - Ivy_2007_Bioorg.Med.Chem_15_678
Author(s) : Ivy Carroll F , Ma W , Navarro HA , Abraham P , Wolckenhauer SA , Damaj MI , Martin BR
Ref : Bioorganic & Medicinal Chemistry , 15 :678 , 2007
Abstract :
PubMedSearch : Ivy_2007_Bioorg.Med.Chem_15_678
PubMedID: 17098430

Title : RhoA, encoding a Rho GTPase, is associated with smoking initiation - Chen_2007_Genes.Brain.Behav_6_689
Author(s) : Chen X , Che Y , Zhang L , Putman AH , Damaj MI , Martin BR , Kendler KS , Miles MF
Ref : Genes Brain Behav , 6 :689 , 2007
Abstract :
PubMedSearch : Chen_2007_Genes.Brain.Behav_6_689
PubMedID: 17284169

Title : Nicotinic regulation of calcium\/calmodulin-dependent protein kinase II activation in the spinal cord - Damaj_2007_J.Pharmacol.Exp.Ther_320_244
Author(s) : Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 320 :244 , 2007
Abstract :
PubMedSearch : Damaj_2007_J.Pharmacol.Exp.Ther_320_244
PubMedID: 17041007

Title : Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice - Damaj_2007_J.Pharmacol.Exp.Ther_320_250
Author(s) : Damaj MI , Siu EC , Sellers EM , Tyndale RF , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 320 :250 , 2007
Abstract :
PubMedSearch : Damaj_2007_J.Pharmacol.Exp.Ther_320_250
PubMedID: 17021260

Title : Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists - Grabus_2006_Psychopharmacology.(Berl)_184_456
Author(s) : Grabus SD , Martin BR , Brown SE , Damaj MI
Ref : Psychopharmacology (Berl) , 184 :456 , 2006
Abstract :
PubMedSearch : Grabus_2006_Psychopharmacology.(Berl)_184_456
PubMedID: 16463055

Title : The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice - Walters_2006_Psychopharmacology.(Berl)_184_339
Author(s) : Walters CL , Brown S , Changeux JP , Martin B , Damaj MI
Ref : Psychopharmacology (Berl) , 184 :339 , 2006
Abstract :
PubMedSearch : Walters_2006_Psychopharmacology.(Berl)_184_339
PubMedID: 16416156

Title : 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs - Abdrakhmanova_2006_Mol.Pharmacol_69_1945
Author(s) : Abdrakhmanova GR , Damaj MI , Carroll FI , Martin BR
Ref : Molecular Pharmacology , 69 :1945 , 2006
Abstract :
PubMedSearch : Abdrakhmanova_2006_Mol.Pharmacol_69_1945
PubMedID: 16505153

Title : Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes - Carroll_2006_J.Med.Chem_49_3244
Author(s) : Carroll FI , Hu X , Navarro HA , Deschamps J , Abdrakhmanova GR , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 49 :3244 , 2006
Abstract :
PubMedSearch : Carroll_2006_J.Med.Chem_49_3244
PubMedID: 16722642

Title : Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats - Wright_2006_Pharmacol.Biochem.Behav_85_507
Author(s) : Wright MJ, Jr. , Vann RE , Gamage TF , Damaj MI , Wiley JL
Ref : Pharmacol Biochem Behav , 85 :507 , 2006
Abstract :
PubMedSearch : Wright_2006_Pharmacol.Biochem.Behav_85_507
PubMedID: 17112574

Title : Nicotine physical dependence and tolerance in the mouse following chronic oral administration - Grabus_2005_Psychopharmacology.(Berl)_178_183
Author(s) : Grabus SD , Martin BR , Batman AM , Tyndale RF , Sellers E , Damaj MI
Ref : Psychopharmacology (Berl) , 178 :183 , 2005
Abstract :
PubMedSearch : Grabus_2005_Psychopharmacology.(Berl)_178_183
PubMedID: 15365686

Title : In vivo characterization of a novel inhibitor of CNS nicotinic receptors - Damaj_2005_Eur.J.Pharmacol_521_43
Author(s) : Damaj MI , Wiley JL , Martin BR , Papke RL
Ref : European Journal of Pharmacology , 521 :43 , 2005
Abstract :
PubMedSearch : Damaj_2005_Eur.J.Pharmacol_521_43
PubMedID: 16181622

Title : 3-(2-Aminoethyl)pyridine analogs as alpha4beta2 nicotinic cholinergic receptor ligands - Dukat_2005_Bioorg.Med.Chem.Lett_15_4308
Author(s) : Dukat M , Ramunno A , Banzi R , Damaj MI , Martin B , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :4308 , 2005
Abstract :
PubMedSearch : Dukat_2005_Bioorg.Med.Chem.Lett_15_4308
PubMedID: 16039854

Title : Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues - Carroll_2005_J.Med.Chem_48_7491
Author(s) : Carroll FI , Brieaddy LE , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 48 :7491 , 2005
Abstract :
PubMedSearch : Carroll_2005_J.Med.Chem_48_7491
PubMedID: 16279810

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists - Carroll_2005_J.Med.Chem_48_1221
Author(s) : Carroll FI , Ma W , Yokota Y , Lee JR , Brieaddy LE , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 48 :1221 , 2005
Abstract :
PubMedSearch : Carroll_2005_J.Med.Chem_48_1221
PubMedID: 15715488

Title : 6-(2-Phenylethyl)nicotine: a novel nicotinic cholinergic receptor ligand - Ramunno_2005_Bioorg.Med.Chem.Lett_15_3237
Author(s) : Ramunno A , Dukat M , Lee M , Young R , El-Zahabi M , Damaj MI , Martin B , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :3237 , 2005
Abstract :
PubMedSearch : Ramunno_2005_Bioorg.Med.Chem.Lett_15_3237
PubMedID: 15925512

Title : Calcium-acting drugs modulate expression and development of chronic tolerance to nicotine-induced antinociception in mice - Damaj_2005_J.Pharmacol.Exp.Ther_315_959
Author(s) : Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 315 :959 , 2005
Abstract :
PubMedSearch : Damaj_2005_J.Pharmacol.Exp.Ther_315_959
PubMedID: 16099928

Title : Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity - Damaj_2005_J.Pharmacol.Exp.Ther_312_780
Author(s) : Damaj MI , Flood P , Ho KK , May EL , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 312 :780 , 2005
Abstract :
PubMedSearch : Damaj_2005_J.Pharmacol.Exp.Ther_312_780
PubMedID: 15356218

Title : Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice - Salmon_2004_Neurosci.Lett_360_73
Author(s) : Salmon AM , Evrard A , Damaj MI , Changeux JP
Ref : Neuroscience Letters , 360 :73 , 2004
Abstract :
PubMedSearch : Salmon_2004_Neurosci.Lett_360_73
PubMedID: 15082182

Title : 3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors - Dogruer_2004_Bioorg.Med.Chem.Lett_14_523
Author(s) : Dogruer D , Lee M , Dukat M , Damaj MI , Martin BR , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :523 , 2004
Abstract :
PubMedSearch : Dogruer_2004_Bioorg.Med.Chem.Lett_14_523
PubMedID: 14698195

Title : (+\/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents - Dukat_2004_Bioorg.Med.Chem.Lett_14_3651
Author(s) : Dukat M , Taroua M , Dahdouh A , Siripurapu U , Damaj MI , Martin BR , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :3651 , 2004
Abstract :
PubMedSearch : Dukat_2004_Bioorg.Med.Chem.Lett_14_3651
PubMedID: 15203136

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist - Carroll_2004_J.Med.Chem_47_4588
Author(s) : Carroll FI , Ware R , Brieaddy LE , Navarro HA , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 47 :4588 , 2004
Abstract :
PubMedSearch : Carroll_2004_J.Med.Chem_47_4588
PubMedID: 15317468

Title : Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors - Damaj_2004_Mol.Pharmacol_66_675
Author(s) : Damaj MI , Carroll FI , Eaton JB , Navarro HA , Blough BE , Mirza S , Lukas RJ , Martin BR
Ref : Molecular Pharmacology , 66 :675 , 2004
Abstract :
PubMedSearch : Damaj_2004_Mol.Pharmacol_66_675
PubMedID: 15322260

Title : Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice - Damaj_2004_Brain.Res_1024_146
Author(s) : Damaj MI , Hunter RG , Martin BR , Kuhar MJ
Ref : Brain Research , 1024 :146 , 2004
Abstract :
PubMedSearch : Damaj_2004_Brain.Res_1024_146
PubMedID: 15451376

Title : Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action - Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633
Author(s) : Lester HA , Fonck C , Tapper AR , McKinney S , Damaj MI , Balogh S , Owens J , Wehner JM , Collins AC , Labarca C
Ref : Curr Opin Drug Discov Devel , 6 :633 , 2003
Abstract :
PubMedSearch : Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633
PubMedID: 14579512

Title : Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors - Ferretti_2003_Bioorg.Med.Chem.Lett_13_733
Author(s) : Ferretti G , Dukat M , Giannella M , Piergentili A , Pigini M , Quaglia W , Damaj MI , Martin BR , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 13 :733 , 2003
Abstract :
PubMedSearch : Ferretti_2003_Bioorg.Med.Chem.Lett_13_733
PubMedID: 12639569

Title : Characterization of spontaneous and precipitated nicotine withdrawal in the mouse - Damaj_2003_J.Pharmacol.Exp.Ther_307_526
Author(s) : Damaj MI , Kao W , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 307 :526 , 2003
Abstract :
PubMedSearch : Damaj_2003_J.Pharmacol.Exp.Ther_307_526
PubMedID: 12970387

Title : Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors - Fonck_2003_J.Neurosci_23_2582
Author(s) : Fonck C , Nashmi R , Deshpande P , Damaj MI , Marks MJ , Riedel A , Schwarz J , Collins AC , Labarca C , Lester HA
Ref : Journal of Neuroscience , 23 :2582 , 2003
Abstract :
PubMedSearch : Fonck_2003_J.Neurosci_23_2582
PubMedID: 12684443

Title : Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice - Damaj_2003_Brain.Res_983_233
Author(s) : Damaj MI , Martin BR , Kuhar MJ
Ref : Brain Research , 983 :233 , 2003
Abstract :
PubMedSearch : Damaj_2003_Brain.Res_983_233
PubMedID: 12914986

Title : A comparison of the binding of three series of nicotinic ligands - Lee_2002_Bioorg.Med.Chem.Lett_12_1989
Author(s) : Lee M , Dukat M , Liao L , Flammia D , Damaj MI , Martin B , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 12 :1989 , 2002
Abstract :
PubMedSearch : Lee_2002_Bioorg.Med.Chem.Lett_12_1989
PubMedID: 12113825

Title : Functional diversity among 5-substituted nicotine analogs\; in vitro and in vivo investigations - Dukat_2002_Eur.J.Pharmacol_435_171
Author(s) : Dukat M , Damaj MI , Young R , Vann R , Collins AC , Marks MJ , Martin BR , Glennon RA
Ref : European Journal of Pharmacology , 435 :171 , 2002
Abstract :
PubMedSearch : Dukat_2002_Eur.J.Pharmacol_435_171
PubMedID: 11821023

Title : (-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine - Dukat_2002_Bioorg.Med.Chem.Lett_12_3005
Author(s) : Dukat M , El-Zahabi M , Ferretti G , Damaj MI , Martin BR , Young R , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 12 :3005 , 2002
Abstract :
PubMedSearch : Dukat_2002_Bioorg.Med.Chem.Lett_12_3005
PubMedID: 12270194

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues - Carroll_2002_J.Med.Chem_45_4755
Author(s) : Carroll FI , Lee JR , Navarro HA , Ma W , Brieaddy LE , Abraham P , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 45 :4755 , 2002
Abstract :
PubMedSearch : Carroll_2002_J.Med.Chem_45_4755
PubMedID: 12361403

Title : Nicotine-like discriminative stimulus effects of bupropion in rats - Wiley_2002_Exp.Clin.Psychopharmacol_10_129
Author(s) : Wiley JL , Lavecchia KL , Martin BR , Damaj MI
Ref : Experimental & Clinical Psychopharmacology , 10 :129 , 2002
Abstract :
PubMedSearch : Wiley_2002_Exp.Clin.Psychopharmacol_10_129
PubMedID: 12022798

Title : Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding - Ferretti_2002_J.Med.Chem_45_4724
Author(s) : Ferretti G , Dukat M , Giannella M , Piergentili A , Pigini M , Quaglia W , Damaj MI , Martin BR , Glennon RA
Ref : Journal of Medicinal Chemistry , 45 :4724 , 2002
Abstract :
PubMedSearch : Ferretti_2002_J.Med.Chem_45_4724
PubMedID: 12361399

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist - Carroll_2001_J.Med.Chem_44_4039
Author(s) : Carroll FI , Lee JR , Navarro HA , Brieaddy LE , Abraham P , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 44 :4039 , 2001
Abstract :
PubMedSearch : Carroll_2001_J.Med.Chem_44_4039
PubMedID: 11708907

Title : Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues - Carroll_2001_J.Med.Chem_44_2229
Author(s) : Carroll FI , Liang F , Navarro HA , Brieaddy LE , Abraham P , Damaj MI , Martin BR
Ref : Journal of Medicinal Chemistry , 44 :2229 , 2001
Abstract :
PubMedSearch : Carroll_2001_J.Med.Chem_44_2229
PubMedID: 11405659

Title : Influence of gender and sex hormones on nicotine acute pharmacological effects in mice - Damaj_2001_J.Pharmacol.Exp.Ther_296_132
Author(s) : Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 296 :132 , 2001
Abstract :
PubMedSearch : Damaj_2001_J.Pharmacol.Exp.Ther_296_132
PubMedID: 11123373

Title : Chain-lengthened and imidazoline analogues of nicotine - Ferretti_2000_Bioorg.Med.Chem.Lett_10_2665
Author(s) : Ferretti G , Dukat M , Giannella M , Piergentili A , Pigini M , Quaglia W , Damaj MI , Martin BR , Glennon RA
Ref : Bioorganic & Medicinal Chemistry Lett , 10 :2665 , 2000
Abstract :
PubMedSearch : Ferretti_2000_Bioorg.Med.Chem.Lett_10_2665
PubMedID: 11128647

Title : The involvement of spinal Ca(2+)\/calmodulin-protein kinase II in nicotine-induced antinociception in mice - Damaj_2000_Eur.J.Pharmacol_404_103
Author(s) : Damaj MI
Ref : European Journal of Pharmacology , 404 :103 , 2000
Abstract :
PubMedSearch : Damaj_2000_Eur.J.Pharmacol_404_103
PubMedID: 10980268

Title : Bupropion is a nicotinic antagonist - Slemmer_2000_J.Pharmacol.Exp.Ther_295_321
Author(s) : Slemmer JE , Martin BR , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 295 :321 , 2000
Abstract :
PubMedSearch : Slemmer_2000_J.Pharmacol.Exp.Ther_295_321
PubMedID: 10991997

Title : The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model - Damaj_2000_Neuropharmacol_39_2785
Author(s) : Damaj MI , Meyer EM , Martin BR
Ref : Neuropharmacology , 39 :2785 , 2000
Abstract :
PubMedSearch : Damaj_2000_Neuropharmacol_39_2785
PubMedID: 11044748

Title : Modulation of morphine analgesia in alphaCGRP mutant mice - Salmon_1999_Neuroreport_10_849
Author(s) : Salmon AM , Damaj MI , Sekine S , Picciotto MR , Marubio L , Changeux JP
Ref : Neuroreport , 10 :849 , 1999
Abstract :
PubMedSearch : Salmon_1999_Neuroreport_10_849
PubMedID: 10208559

Title : Lobeline: structure-affinity investigation of nicotinic acetylcholinergic receptor binding - Flammia_1999_J.Med.Chem_42_3726
Author(s) : Flammia D , Dukat M , Damaj MI , Martin B , Glennon RA
Ref : Journal of Medicinal Chemistry , 42 :3726 , 1999
Abstract :
PubMedSearch : Flammia_1999_J.Med.Chem_42_3726
PubMedID: 10479304

Title : Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist - Damaj_1999_J.Pharmacol.Exp.Ther_291_390
Author(s) : Damaj MI , Glassco W , Aceto MD , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 291 :390 , 1999
Abstract :
PubMedSearch : Damaj_1999_J.Pharmacol.Exp.Ther_291_390
PubMedID: 10490929

Title : Pharmacological characterization of nicotine-induced seizures in mice - Damaj_1999_J.Pharmacol.Exp.Ther_291_1284
Author(s) : Damaj MI , Glassco W , Dukat M , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 291 :1284 , 1999
Abstract :
PubMedSearch : Damaj_1999_J.Pharmacol.Exp.Ther_291_1284
PubMedID: 10565853

Title : Reduced antinociception in mice lacking neuronal nicotinic receptor subunits - Marubio_1999_Nature_398_805
Author(s) : Marubio LM , del Mar Arroyo-Jimenez M , Cordero-Erausquin M , Lena C , Le Novere N , de Kerchove d'Exaerde A , Huchet M , Damaj MI , Changeux JP
Ref : Nature , 398 :805 , 1999
Abstract :
PubMedSearch : Marubio_1999_Nature_398_805
PubMedID: 10235262

Title : Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs - Damaj_1999_J.Pharmacol.Exp.Ther_289_1229
Author(s) : Damaj MI , Slemmer JE , Carroll FI , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 289 :1229 , 1999
Abstract :
PubMedSearch : Damaj_1999_J.Pharmacol.Exp.Ther_289_1229
PubMedID: 10336510

Title : Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice - Damaj_1998_J.Pharmacol.Exp.Ther_284_1058
Author(s) : Damaj MI , Fei-Yin M , Dukat M , Glassco W , Glennon RA , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 284 :1058 , 1998
Abstract :
PubMedSearch : Damaj_1998_J.Pharmacol.Exp.Ther_284_1058
PubMedID: 9495867

Title : Analysis of developmental evolution of synapses in CGRP knock-out mice -
Author(s) : Salmon AM , Sekine S , Picciotto MR , Damaj MI , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :488 , 1998
PubMedID:

Title : Altered behavioral sensitivity of Ca(2+)-modulating drugs after chronic nicotine administration in mice - Damaj_1997_Eur.J.Pharmacol_322_129
Author(s) : Damaj MI
Ref : European Journal of Pharmacology , 322 :129 , 1997
Abstract :
PubMedSearch : Damaj_1997_Eur.J.Pharmacol_322_129
PubMedID: 9098679

Title : Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog - Damaj_1997_J.Pharmacol.Exp.Ther_282_1425
Author(s) : Damaj MI , Glassco W , Marks MJ , Slobe B , James JR , May EL , Rosecrans JA , Collins AC , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 282 :1425 , 1997
Abstract :
PubMedSearch : Damaj_1997_J.Pharmacol.Exp.Ther_282_1425
PubMedID: 9316856

Title : Pharmacology of lobeline, a nicotinic receptor ligand - Damaj_1997_J.Pharmacol.Exp.Ther_282_410
Author(s) : Damaj MI , Patrick GS , Creasy KR , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 282 :410 , 1997
Abstract :
PubMedSearch : Damaj_1997_J.Pharmacol.Exp.Ther_282_410
PubMedID: 9223582

Title : Characterization and modulation of acute tolerance to nicotine in mice - Damaj_1996_J.Pharmacol.Exp.Ther_277_454
Author(s) : Damaj MI , Welch SP , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 277 :454 , 1996
Abstract :
PubMedSearch : Damaj_1996_J.Pharmacol.Exp.Ther_277_454
PubMedID: 8613954

Title : Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice - Damaj_1996_Eur.J.Pharmacol_300_51
Author(s) : Damaj MI , Martin BR
Ref : European Journal of Pharmacology , 300 :51 , 1996
Abstract :
PubMedSearch : Damaj_1996_Eur.J.Pharmacol_300_51
PubMedID: 8741164

Title : In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice - Damaj_1995_Psychopharmacology.(Berl)_117_67
Author(s) : Damaj MI , Welch SP , Martin BR
Ref : Psychopharmacology (Berl) , 117 :67 , 1995
Abstract :
PubMedSearch : Damaj_1995_Psychopharmacology.(Berl)_117_67
PubMedID: 7724704

Title : Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist - Damaj_1995_Psychopharmacology.(Berl)_120_483
Author(s) : Damaj MI , Creasy KR , Welch SP , Rosecrans JA , Aceto MD , Martin BR
Ref : Psychopharmacology (Berl) , 120 :483 , 1995
Abstract :
PubMedSearch : Damaj_1995_Psychopharmacology.(Berl)_120_483
PubMedID: 8539331

Title : Pharmacological effects of epibatidine optical enantiomers - Damaj_1994_Brain.Res_664_34
Author(s) : Damaj MI , Creasy KR , Grove AD , Rosecrans JA , Martin BR
Ref : Brain Research , 664 :34 , 1994
Abstract :
PubMedSearch : Damaj_1994_Brain.Res_664_34
PubMedID: 7895043

Title : Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice - Damaj_1994_Brain.Res.Bull_33_199
Author(s) : Damaj MI , Glennon RA , Martin BR
Ref : Brain Research Bulletin , 33 :199 , 1994
Abstract :
PubMedSearch : Damaj_1994_Brain.Res.Bull_33_199
PubMedID: 8275340

Title : Nicotine-induced antinociception in mice: role of G-proteins and adenylate cyclase - Damaj_1994_Pharmacol.Biochem.Behav_48_37
Author(s) : Damaj MI , Welch SP , Martin BR
Ref : Pharmacol Biochem Behav , 48 :37 , 1994
Abstract :
PubMedSearch : Damaj_1994_Pharmacol.Biochem.Behav_48_37
PubMedID: 8029303

Title : Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility - Damaj_1993_Drug.Alcohol.Depend_32_73
Author(s) : Damaj MI , Martin BR
Ref : Drug Alcohol Depend , 32 :73 , 1993
Abstract :
PubMedSearch : Damaj_1993_Drug.Alcohol.Depend_32_73
PubMedID: 7683598

Title : Is the dopaminergic system involved in the central effects of nicotine in mice? - Damaj_1993_Psychopharmacology.(Berl)_111_106
Author(s) : Damaj MI , Martin BR
Ref : Psychopharmacology (Berl) , 111 :106 , 1993
Abstract :
PubMedSearch : Damaj_1993_Psychopharmacology.(Berl)_111_106
PubMedID: 7870924

Title : Involvement of calcium and L-type channels in nicotine-induced antinociception - Damaj_1993_J.Pharmacol.Exp.Ther_266_1330
Author(s) : Damaj MI , Welch SP , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 266 :1330 , 1993
Abstract :
PubMedSearch : Damaj_1993_J.Pharmacol.Exp.Ther_266_1330
PubMedID: 7690401